A5100382842- Respiratory viral infections research
- Influenza Virus Research Studies
- Vibration Control and Rheological Fluids
- Soft Robotics and Applications
- Neonatal Respiratory Health Research
- Pneumonia and Respiratory Infections
- Anatomy and Medical Technology
- Streptococcal Infections and Treatments
- Video Surveillance and Tracking Methods
- Spine and Intervertebral Disc Pathology
- Advanced Algorithms and Applications
- Congenital Diaphragmatic Hernia Studies
- Surgical Simulation and Training
- Neonatal and Maternal Infections
- Spinal Fractures and Fixation Techniques
- 3D Shape Modeling and Analysis
- Cervical and Thoracic Myelopathy
- Gear and Bearing Dynamics Analysis
- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- Congenital Anomalies and Fetal Surgery
- Simulation and Modeling Applications
- Industrial Technology and Control Systems
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Advanced Sensor and Control Systems
Southern Medical University
2012-2025
Nanfang Hospital
2012-2025
The First People’s Hospital of Lianyungang
2018-2025
Qilu University of Technology
2020-2024
Shandong Academy of Sciences
2020-2024
State Key Laboratory of Chemobiosensing and Chemometrics
2024
City of Hope
2023-2024
Beckman Research Institute
2024
China University of Mining and Technology
2008-2024
Universiti Teknologi MARA
2024
Human respiratory syncytial virus (HRSV) is the main cause of acute lower infections in children under 2 years age and causes repeated throughout life. We investigated genetic variability RSV-A circulating Ontario during 2010-2011 winter season by sequencing phylogenetic analysis G glycoprotein gene.Among 201 consecutive RSV isolates studied, (55.7%) was more commonly observed than RSV-B (42.3%). 59.8% 90.1% were among ≤12 months ≤5 old, respectively. On second hypervariable region 112...
The apolipoprotein E E4 allele of the APOE gene is strongest genetic factor for late-onset Alzheimer disease (LOAD). There compelling evidence that apoE influences (AD) in large part by affecting amyloid β (Aβ) aggregation and clearance; however, molecular mechanism underlying these findings remains largely unknown. Herein, we tested whether anti–human antibodies can decrease Aβ pathology mice producing both human apoE4, investigated effects. We utilized APPPS1-21 crossed to apoE4-knockin...
Abstract Development of the mammalian lung is predicated on cross-communications between two highly interactive tissues, endodermally derived epithelium and mesodermally pulmonary mesenchyme. While much attention has been paid for epithelium, mesenchyme, partly due to lack specific tractable markers remains under-investigated. The mesenchyme from lateral plate mesoderm principal recipient Hedgehog (Hh) signaling, a morphogenetic network that regulates multiple aspects embryonic development....
<i>Background and Aim:</i> Differentiating Crohn’s disease from intestinal tuberculosis often challenges clinicians in countries where coexist. The aim of this study was to screen out clinical, endoscopic histological features which may be helpful distinguishing tuberculosis. <i>Methods:</i> 43 patients with a confirmed diagnosis 53 were recruited for study. Their subjected univariate multivariate analyses. <i>Results:</i> On analysis, the hematochezia,...
ABSTRACT An outbreak of type emm59 invasive group A Streptococcus (iGAS) disease was declared in 2008 Thunder Bay District, Northwestern Ontario, 2 years after a countrywide epidemic recognized Canada. Despite declining number infections since 2010, numerous cases iGAS continue to be reported the area. We collected clinical information on all recorded District from 2013. also emm typed and sequenced genomes available strains isolated 2011 2013 severe soft tissue infections. used whole-genome...
Immunocompromised patients are predisposed to infections caused by influenza virus. Influenza virus may produce considerable morbidity, including protracted illness and prolonged viral shedding in these patients, thus prompting higher doses courses of antiviral therapy. This approach promote the emergence resistant strains. Characterization neuraminidase (NA) inhibitor (NAI)-resistant strains A is essential for documenting causes resistance. In this study, using quantitative real-time PCR...
In order to prepare magnetorheological fluid with excellent sedimentation stability, various surfactants are applied coat carbonyl iron powder. The prepared shows stability when the respectively sodium lauryl alcohol phosphate, compound fatty acid methyl ester sulfonate, ethylene glycol monostearate and glyceride monostearate. Orthogonal tests carried out for optimal combination of thixotropic agent. experimental results show that additives MRF is 1.5 wt% 1.0 MES, monostearate, glycerol...
Open AccessCCS ChemistryRESEARCH ARTICLES11 Apr 2024CO2 Capture in Liquid Phase and Room–Temperature Release Concentration Using Mechanical Power Aimin Li, Yuanchu Liu, Ke Luo Qing He Li , Liu https://doi.org/10.31635/ccschem.024.202404292 SectionsSupplemental MaterialAboutPDF ToolsAdd to favoritesDownload CitationsTrack Citations ShareFacebookTwitterLinked InEmail Development of advanced materials with high CO2 capture capacity and, inter alia, superior regenerability low energy consumption...
Serotype IV group B Streptococcus (GBS) is emerging in Canada and the United States with rates as high 5% of total burden adult invasive GBS disease. To understand this emergence, we studied population structure assessed antimicrobial susceptibility serotype isolates causing infection Manitoba Saskatchewan, Canada, between 2010 2014. Whole-genome sequencing was used to determine multilocus sequence typing information identify genes encoding resistance 85 strains. Antimicrobial testing...
Breeders have focused on yellow-seeded Brassica napus (rapeseed) for its better quality compared with the black-seeded variety. Moreover, flavonoids been associated this kind of rapeseed. In study, we applied lipid chromatography-electrospray ionization mass spectrometry (LC-ESI-MS(n)) to compare in developing seeds natural B. and introgression lines selected from progenies napus-Sinapis alba somatic hybrids. Aside most abundant phenolic compounds (sinapine sinapic acid) 1,...
MiR-452-5p plays an essential role in the development of a variety tumors, but little is known about its biological function and mechanism colorectal cancer (CRC).The expression levels miR-452-5p CRC tissues cells were detected by real-time quantitative PCR (qRT-PCR). Besides, effects on investigated functional experiments vitro vivo. Furthermore, bioinformatics analysis, dual-luciferase reporter assay, chromatin immunecipitation western blotting recovery implemented to investigate...
Abstract Introduction Psittacosis can cause severe community-acquired pneumonia (CAP). The clinical manifestations of psittacosis range from subclinical to fulminant with multi-organ failure. It is essential summarize the characteristic patients accompanied by acute hypoxic respiratory failure (AHRF). Methods This retrospective study included caused CAP AHRF 19 tertiary hospitals China. We recorded data, antimicrobial therapy, support, complications, and outcomes. Chlamydia psittaci was...
Ceftazidime-avibactam was approved in patients with hospital-acquired pneumonia (HAP), including ventilator-associated (VAP), based on the multinational Phase 3 REPROVE study. This study assessed efficacy and safety of ceftazidime-avibactam Chinese adults HAP/VAP. a 4, prospective, multi-centre, open-label study, conducted at 42 sites China. Patients HAP/VAP received 2.5 g by 2-hour IV infusion every 8 hours for 7-14 days. Primary endpoint clinical response test-of-cure (TOC) visit modified...
The development of museum cultural and creative industries (MCCIs), defined as economic activities integrating heritage with product design, has become integral to progress under the Chinese government's advocacy public attention. This study integrates social identity theory[1] value-belief-norm theory[2] investigate how souvenirs in Northwest China mediate pro-environmental behaviors. Through comparative analysis, focusing on Ningxia Museum, this research explores innovative provincial...
Colon adenocarcinoma (COAD) remains a major global health challenge with poor prognosis despite advances in treatment, underscoring the need for new biomarkers. As novel mode of cell death, cuproptosis is thought to be potentially involved development cancer. However, particularly as role cuproptosis-related genes (CRGs) COAD and therapy unclear. We analyzed RNA sequencing data from The Cancer Genome Atlas COAD, focusing on CRG expression patterns their clinicopathological correlations....
Previous studies on the association between non-skimmed milk consumption and non-alcoholic fatty liver disease (NAFLD) have reported inconsistent findings, with some suggesting an increased risk others indicating a protective effect. Moreover, as research focus has shifted globally from NAFLD to metabolic dysfunction-associated (MAFLD), there remains limited evidence relationship MAFLD. The objective of this cross-sectional study was investigate using data National Health Nutrition...
Abstract The yield stress used to describe the strength of rheological effects is most important mechanical property index for magnetorheological fluids. macroscopic originates from microscopic inter-particle electromagnetic force and particle arrangement, existing constitutive model based on single-chain model. However, single chains become double or even multiple when concentration magnetic field increases. It assumed in research particles arrange because evolution mechanism cannot be...
Bcl-2 (B cell lymphoma/leukemia gene-2) is the first proto-oncogene recognized to function by inhibiting programmed death/apoptosis. Although much known about anti-apoptotic ability of Bcl-2, little information available concerning its in other cellular processes, such as differentiation. In this study, stable lines from pre-malignant MCF10ATG3B mammary epithelial cells, a line derived human proliferative breast disease model, express exogenous was established. CMV promoter driven expression...
The performance of robotic end-effector movements can reflect the user's operation skill difference in robot-assisted minimally invasive surgery. This study quantified trade-off speed-accuracy-stability by kinematic analysis to assess motion control users with different levels experience.Using 'MicroHand S' system, 10 experts, residents and novices performed single-hand test bimanual coordination test. Eight metrics based on end-effectors were applied evaluate users' performance.In test,...
Myoglobin is one of the most commonly used cardiac biomarkers for clinical diagnosis acute myocardial infarction, which leading cause mortality worldwide.
Abstract Adequacy of the current clinical definition institutional influenza outbreaks is unclear. We performed a retrospective genome sequencing and epidemiologic analysis that occurred during 2014–15 season in Toronto, Canada. sequenced 2 earliest submitted samples positive for A(H3N2) from each 38 reported long-term care facilities. Genome showed most outbreak pairs identified by using were highly related. Inclusion surveillance demonstrated sources likely introductions broader...
A community-based intervention trial was carried out to evaluate the effectiveness of alphamethrin-impregnated bed nets for control Plasmodium vivax malaria and its vector in an area moderate endemicity southern Henan province, central China 1990. Malaria incidence significantly lower group than comparison (2.03 vs. 3.57 per 100 person-years at risk). The protective efficacy 43%. prevalence parasitaemia among children under 10 years old about one-quarter that (0·93% 3·25% 0·71% 1·96% after...
Human metapneumovirus (hMPV) has been identified previously as a cause of respiratory outbreaks in adults, including the elderly. The objective this study was to document that were caused by hMPV Ontario, Canada and identify various circulating genotypes during April 2009-February 2012. majority part adults (>65 years). Total nucleic acid extraction done on 123 residual anonymized clinical specimens from 51 different outbreaks. Specimens subjected PCR amplification Sanger sequencing...