- Renal Diseases and Glomerulopathies
- Lung Cancer Treatments and Mutations
- Infant Nutrition and Health
- Central Venous Catheters and Hemodialysis
- Acute Kidney Injury Research
- Infant Development and Preterm Care
- Dialysis and Renal Disease Management
- Lung Cancer Research Studies
- Drug-Induced Hepatotoxicity and Protection
- Neonatal and Maternal Infections
- Vascular Procedures and Complications
- Women's cancer prevention and management
- Inflammatory Biomarkers in Disease Prognosis
- Toxoplasma gondii Research Studies
- Intracerebral and Subarachnoid Hemorrhage Research
- IgG4-Related and Inflammatory Diseases
- Parasites and Host Interactions
- Anesthesia and Pain Management
- Intraperitoneal and Appendiceal Malignancies
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Cancer, Lipids, and Metabolism
- Botulinum Toxin and Related Neurological Disorders
- Nausea and vomiting management
- Hypothalamic control of reproductive hormones
- Cancer Risks and Factors
Anhui Medical University
2011-2024
Anhui Provincial Children's Hospital
2021-2024
Hunan Children's Hospital
2024
Central South University
2024
Foshan Maternity and Child Health Care Hospital
2022
Southern Medical University
2022
First Affiliated Hospital of Guangzhou University of Chinese Medicine
2022
Southwest Hospital
2022
University of Shanghai for Science and Technology
2022
Shanghai University
2022
Objective: To evaluate the psychopathological symptoms, suicide, and self-harming behaviors among students with early, on-time, late menarche in high school college association of early these disorders. Methods: The design consisted a cross-sectional study 5597 2768 students. Menarche age, suboptimal mental health status, anxiety, depression, were obtained by self-report questionnaire. Results: In students, all disorders occurred at significantly higher frequency those than on-time menarche....
Objective: Falls often occur in patients with diabetic neuropathy due to biomechanical alternation. The implication of peripheral (DPN) on gait and balance remains poorly understood. Methods: A total 11 dynamic gait, electrophysiological parameters were evaluated 176 participants. compared between groups. Results: Stride length stride velocity significantly lower all subgroups DPN healthy subjects (p< 0.05). Stance phase double support higher, but swing across than Under eyes-open standing,...
Neurological deterioration after intracerebral hemorrhage (ICH) is thought to be closely related increased intracranial pressure (ICP), decreased cerebral blood flow (CBF), and brain metabolism. Transcranial Doppler (TCD) increasingly used as an indirect measure of ICP, quantitative EEG (QEEG) can reflect the coupling CBF We aimed combine TCD QEEG comprehensively assess function ICH provide prognostic diagnosis.We prospectively enrolled patients with severe acute supratentorial (SAS)-ICH...
This study explores the protective mechanism of angiotensin (1-7) [Ang-(1-7)] on kidneys by examining its effects renal histomorphology, inflammatory response, oxidative stress, and NF-κB signaling in mice suffering from sepsis-induced acute kidney injury. A injury mouse model was established intracervically injecting lipopolysaccharides (LPS group), followed administration Ang-(1-7) [LPS + group]. The serum levels urea nitrogen, creatinine cystatin. c were measured with an automatic...
A growing body of evidence suggests that tumor associated macrophages (TAMs) are deeply involved in the hepatocellular carcinoma (HCC) proliferation, and account for large proportion infiltrated cells tissues play a major role promotion growth. On other hand, studies have demonstrated Toxoplasma gondii virulence- molecule dense granule protein (ToxoGRA15II) tends to induce classically activated (M1) differentiation. Thus we explored M1 induced by ToxoGRA15II vitro its inhibitory impact on...
Epidermal growth factor receptor (EGFR) mutations are more common in non-small cell lung cancer (NSCLC) and female patients of East Asian origin. Therefore, the present study investigated presence EGFR advanced NSCLC, assessed its correlation with clinicopathologic factors, including expression estrogen receptor-β (ER-β) patient prognosis. The performed a retrospective analysis 83 stage IIIB-IV NSCLC. ER-β p53 were examined using immunohistochemical methods. evaluated amplification...
To explore the changes of inflammatory and oxidative stress responses in Henoch-Schönlein purpura (HSP) children, further analyzed therapeutic effects mechanisms hemoperfusion (HP) on HSP with severe gastrointestinal (GI) involvement.There were 200 children divided into three groups according to their clinical manifestations: 60 without GI renal involvement group, 80 HSPN group. The group was subdivided conventional treatment (n = 30) HP groups. Thirty who visited department healthcare for...
Frequently-relapsing/steroid-dependent nephrotic syndrome (FRSDNS) leads to steroid toxicity impairing quality of life (QOL), thus prompting the use steroid-sparing drugs.51 FRSDNS children not previously treated with agents were randomized receive rituximab, cyclophosphamide, or tacrolimus. Clinical findings and QOL evaluated before after treatment.The mean relapse rate in all groups declined six months treatment, however, 1-year relapse-free survival rate, number relapses, cumulative...
Previous studies have demonstrated an association between human papillomavirus (HPV) and mutations in the epidermal growth factor receptor (EGFR) gene lung cancer patients; however, few investigated this advanced adenocarcinoma patients undergoing gefitinib treatment. The present study HPV EGFR patients. A total of 95 were enrolled study. infection status presence tumor tissue was evaluated. Patient clinical characteristics also determined compared with mutation to analyze their impact on...
We aimed to identify the factors associated with necrotizing enterocolitis (NEC) and assess associations of initial empirical antibiotic therapy (IEAT) duration duration/hospital stay ratio (A/H ratio) before NEC subsequent in very low birth weight (VLBW) infants gestational age less than 32 weeks without proven sepsis.A retrospective study was conducted at NICU First Affiliated Hospital Medical University Anhui province from June 2015 May 2022, 567 VLBW were included study. divided into...
Background Vacuum bell (VB) is a technique to treat pectus excavatum in children. Its effectiveness and influencing factors, however, remain under investigated. The aim of this study was examine the therapeutic effect its factors VB children with excavatum. Methods A cross-sectional observational conducted. Parents who underwent treatment between January 2018 December 2019 were recruited. survey designed based on previously related studies delivered parents September–October 2021. analyzed...
Human papilloma virus (HPV) infection has previously been reported to be associated with TP53 and TP16 expression in Japanese Taiwanese patients lung cancer, but data for advanced non-small cell cancer (NSCLC) is limited. The present study examined the association between HPV Chinese NSCLC. DNA was detected 20 out of 83 (24%) tumors, observed more frequently non-smokers, lymph node metastasis, poorly differentiated tumors (P=0.048, P=0.044 P=0.024, respectively). Thirteen (65%) HPV-infected...
BACKGROUND AND OBJECTIVES Arteriovenous fistulae (AVF) and grafts (AVG) are preferred permanent vascular access (PVA) for chronic hemodialysis (HD) patients. Our objective was to examine the change in markers of HD efficacy after successful establishment a PVA among children who started with tunneled cuffed catheter (TCC). MATERIALS METHODS Retrospective chart reviews were completed on patients from 20 pediatric dialysis centers. All used TCC prior AVF/AVG, each patient acted as his/her own...
Background: Dexmedetomidine could be an ideal adjuvant to propofol during gastrointestinal endoscopy because it provides both analgesia and sedation without respiratory depression. This study investigates the effect of different doses dexmedetomidine on median effective concentration endoscopy. Methods: 90 adult patients were randomly assigned Group Control , DEX0.5 (0.5 μg/kg dexmedetomidine), or DEX1.0 (1.0 dexmedetomidine) . Anaesthesia was implemented by plasma target-controlled infusion...
Introduction Approximately 80% of children, adolescents and young adults (CAYA) cancer patients are expected to fully recover survive for five years or more. The reproductive health is a particular area their concern. Evidence demonstrates that previous therapeutic treatments comorbidities may have harmful effects on female fertility delivery outcomes, which will significantly affect patient quality life. However, these reports heterogeneous. Therefore, the purpose this study provide...
Background: Necrotizing enterocolitis (NEC) is a common life-threatening disease in very low birth-weight (VLBW) infants. Probiotic prophylaxis often used the VLBW infants as protective factor. Objectives: This retrospective study assessed risk factors of NEC and observed effect probiotic duration on NEC. Methods: The encompassed 237 neonates admitted to NICU First Affiliated Hospital Anhui Medical University, Province, who received prophylaxis. In this study, participants’ clinical...