A5010459902- Blood Pressure and Hypertension Studies
- Birth, Development, and Health
- Dialysis and Renal Disease Management
- Renal function and acid-base balance
- Sodium Intake and Health
- Hormonal Regulation and Hypertension
- Heart Rate Variability and Autonomic Control
- Cardiovascular Health and Disease Prevention
- Hemodynamic Monitoring and Therapy
- Cardiovascular Syncope and Autonomic Disorders
- Chronic Kidney Disease and Diabetes
- Pregnancy and preeclampsia studies
- Neonatal Respiratory Health Research
- Central Venous Catheters and Hemodialysis
- Renal Diseases and Glomerulopathies
- Pharmacological Effects and Toxicity Studies
- Pediatric Urology and Nephrology Studies
- Neonatal Health and Biochemistry
- Cardiac, Anesthesia and Surgical Outcomes
- Pharmaceutical studies and practices
- Adolescent and Pediatric Healthcare
- Pharmacology and Obesity Treatment
- Diet and metabolism studies
- Renal and Vascular Pathologies
- Renal Transplantation Outcomes and Treatments
Seattle Children's Hospital
2016-2025
University of Washington
2016-2025
Seattle University
2013-2024
Albert Einstein College of Medicine
2001-2023
Children's Hospital at Montefiore
2001-2023
Boston Children's Museum
2003-2023
University of Michigan–Ann Arbor
1997-2023
University of Alabama at Birmingham
2002-2023
St. Christopher's Hospital for Children
1992-2023
Dana-Farber Cancer Institute
2023
These pediatric hypertension guidelines are an update to the 2004 "Fourth Report on Diagnosis, Evaluation, and Treatment of High Blood Pressure in Children Adolescents." Significant changes these include (1) replacement term "prehypertension" with "elevated blood pressure," (2) new normative pressure (BP) tables based normal-weight children, (3) a simplified screening table for identifying BPs needing further evaluation, (4) BP classification adolescents ≥13 years age that aligns forthcoming...
Left ventricular hypertrophy (LVH) associates with increased risk for cardiovascular disease. Hypertension leads to LVH in adults, but its role the pathogenesis of children is not as well established. To examine left mass and evaluate factors associated stages 2 through 4 chronic kidney disease (CKD), we analyzed cross-sectional data from who had baseline echocardiography (n = 366) underwent ambulatory BP monitoring 226) a part observational Chronic Kidney Disease Children (CKiD) cohort...
To characterize the distribution of blood pressure (BP), prevalence, and risk factors for hypertension in pediatric chronic kidney disease, we conducted a cross-sectional analysis baseline BPs 432 children (mean age 11 years; 60% male; mean glomerular filtration rate 44 mL/min per 1.73 m 2 ) enrolled Chronic Kidney Disease Children cohort study. were obtained using an aneroid sphygmomanometer. Glomerular was measured by iohexol disappearance. Elevated BP defined as ≥90th percentile age,...
Ambulatory blood pressure (BP) monitoring (ABPM) is the best method of detecting abnormal BP in patients with chronic kidney disease (CKD), whose hypertension may be missed casual measurements. We report ABPM findings 332 children 1 year after entry Chronic Kidney Disease Children cohort study. All subjects underwent and ambulatory measurement. was categorized based on results into normal (42%), white-coat (4%), masked (35%), (14%) hypertension. Only half had a ABPM. load elevated (>25%)...
Most information describing hypertension in the young comes from single-center reports. To better understand contemporary demographic and clinical characteristics of hypertensive children adolescents, we examined baseline data on 351 aged 1 to <17 years old who were enrolled 2 multicenter trials valsartan. Anthropometric, laboratory, at randomization was extracted databases. Summary variables created compared for 3 age groups: <6 (n=90), 6 <12 (n=131), 12 (n=130). Comparisons also...
Development of CKD may be programmed prenatally. We sought to determine the association childhood with prenatal risk factors, including birth weight, maternal diabetes mellitus (DM), and overweight/obesity. conducted a population-based, case-control study 1994 patients (<21 years age at diagnosis) 20,032 controls in Washington state. linked infant characteristics records from 1987 2008 hospital discharge data used logistic regression analysis assess factors CKD. The prevalence was 126.7...
Background and objectives Congenital anomalies of the kidney urinary tract genetic disorders cause most cases CKD in children. This study evaluated relationships between baseline proteinuria BP longitudinal changes GFR children with these nonglomerular causes CKD. Design, setting, participants, & measurements Urine protein-to-creatinine ratio, casual systolic diastolic (normalized for age, sex, height), decline were assessed prospective Children cohort study. Results A total 522 children,...
In adults, increased carotid intima-media thickness (cIMT) as assessed by ultrasonography is a valid predictor of cardiovascular events. Children with CKD are known to be at risk. This study sought identify risk factors associated cIMT in children CKD.This was cross-sectional analysis obtained after 12 months follow-up 101 aged 2-18 years mild moderate (median GFR 42.9 ml/min per 1.73 m(2)) the Chronic Kidney Disease cohort enrolled between April 2005 and September 2009 97 healthy pediatric...
Hypertension is associated with left ventricular hypertrophy (LVH), a risk factor for cardiovascular events. Since events in youth are rare, hypertension has historically been defined by the 95th percentile of normal blood pressure (BP) distribution healthy children. The optimal BP LVH unknown. We aimed to determine association systolic (SBP) percentile, independent obesity, on mass index (LVMI), and estimate which SBP best predicts youth. evaluated SBP, anthropometrics, echocardiogram 303...