A5007129670- Bipolar Disorder and Treatment
- Adolescent and Pediatric Healthcare
- Child and Adolescent Psychosocial and Emotional Development
- Functional Brain Connectivity Studies
- Schizophrenia research and treatment
- Tryptophan and brain disorders
- Suicide and Self-Harm Studies
- Electroconvulsive Therapy Studies
- Electrolyte and hormonal disorders
- Attention Deficit Hyperactivity Disorder
- Mental Health Research Topics
- Maternal Mental Health During Pregnancy and Postpartum
- Genetics and Neurodevelopmental Disorders
- Advanced MRI Techniques and Applications
- Advanced Neuroimaging Techniques and Applications
- Eating Disorders and Behaviors
- Sleep and related disorders
- Blood Pressure and Hypertension Studies
- Cardiac Health and Mental Health
- Mental Health Treatment and Access
- Family Support in Illness
- Child Nutrition and Feeding Issues
- Stuttering Research and Treatment
- Treatment of Major Depression
- Diet and metabolism studies
University of Toronto
2016-2025
Centre for Addiction and Mental Health
2019-2025
Sunnybrook Health Science Centre
2015-2024
Health Sciences Centre
2015-2024
Canada Research Chairs
2015-2024
Addiction Research Foundation
2024
Sunnybrook Research Institute
2015-2023
Baycrest Hospital
2019-2023
University of California, San Diego
2022-2023
Oslo University Hospital
2023
The Canadian Network for Mood and Anxiety Treatments (CANMAT) previously published treatment guidelines bipolar disorder in 2005, along with international commentaries subsequent updates 2007, 2009, 2013. last two were collaboration the International Society Bipolar Disorders (ISBD). These 2018 CANMAT ISBD Treatment Guidelines represent significant advances field since full edition was including to diagnosis management as well new research into pharmacological psychological treatments. have...
Yatham LN, Kennedy SH, Parikh SV, Schaffer A, Beaulieu S, Alda M, O’Donovan C, MacQueen G, McIntyre RS, Sharma V, Ravindran Young LT, Milev R, Bond DJ, Frey BN, Goldstein BI, Lafer B, Birmaher Ha K, Nolen WA, Berk M. Canadian Network for Mood and Anxiety Treatments (CANMAT) International Society Bipolar Disorders (ISBD) collaborative update of CANMAT guidelines the management patients with bipolar disorder: 2013. Disord 2012: 00: 000–000. © 2012 John Wiley & Sons A/S.Published by...
The authors sought to assess the longitudinal course of youths with bipolar spectrum disorders over a 4-year period.At total 413 (ages 7-17 years) I disorder (N=244), II (N=28), and not otherwise specified (N=141) were enrolled in study. Symptoms ascertained retrospectively on average every 9.4 months for 4 years using Longitudinal Interval Follow-Up Evaluation. Rates time recovery recurrence week-by-week symptomatic status analyzed.Approximately 2.5 after onset their index episode, 81.5%...
Whether offspring of parents with bipolar disorder (BP) are at specifically high risk to develop BP and other psychiatric disorders has not been adequately studied.To evaluate lifetime prevalence specificity in BP-I BP-II.Offspring aged 6 18 years who have community control subjects were interviewed standardized instruments. All research staff except the statistician blind parental diagnoses.Parents recruited primarily through advertisement outpatient clinics. Control ascertained by...
Objective: The authors sought to identify diagnostic risk factors of manic, mixed, or hypomanic episodes in the offspring parents with bipolar disorder (“high-risk offspring”). Method: High-risk 6–18 years old (N=391) and demographically matched (N=248) community without were assessed longitudinally standardized instruments by staff blind parental diagnoses. Follow-up assessments completed 91% (mean follow-up interval, 2.5 years; mean duration, 6.8 years). Results: Compared offspring,...
Objective: The authors sought to assess the longitudinal course of youths with bipolar spectrum disorders over a 4-year period. Method: At total 413 (ages 7–17 years) I disorder (N=244), II (N=28), and not otherwise specified (N=141) were enrolled in study. Symptoms ascertained retrospectively on average every 9.4 months for 4 years using Longitudinal Interval Follow-Up Evaluation. Rates time recovery recurrence week-by-week symptomatic status analyzed. Results: Approximately 2.5 after onset...
The authors sought to assess dimensional symptomatic predictors of new-onset bipolar spectrum disorders in youths at familial risk disorder ("at-risk" youths).Offspring 6-18 years old parents with I or II (N=359) and community comparison offspring (N=220) were recruited. At baseline, 8.4% the had a disorder. Over 8 years, 14.7% for whom follow-up data available (44/299) developed (15 disorder). Measures collected baseline reduced using factor analyses, factors (both visit prior conversion...
Objective: Despite ample evidence of excess cardiovascular mortality in bipolar disorder (BD), few studies have demonstrated increased prevalence disease (CVD) and/or hypertension (HTN) BD. We therefore examined this topic a representative epidemiologic sample. Method: The 2001–2002 National Epidemiologic Survey on Alcohol and Related Conditions was used to determine whether physician‐diagnosed CVD HTN is elevated among subjects with lifetime I (BD‐I), are prevalent at earlier ages BD‐I....
<h3>Context</h3>Individuals with early onset of bipolar disorder are at high risk for suicide. Yet, no study to date has examined factors associated prospective suicide attempts among youth disorder.<h3>Objective</h3>To examine past, intake, and follow-up predictors prospectively observed disorder.<h3>Design</h3>We interviewed subjects, on average, every 9 months over a mean 5 years using the Longitudinal Interval Follow-up Evaluation.<h3>Setting</h3>Outpatient inpatient units 3 university...
Goldstein BI, Liu S-M, Zivkovic N, Schaffer A, Chien L-C, Blanco C. The burden of obesity among adults with bipolar disorder in the United States.Bipolar Disord 2011: 13: 387–395. © 2011 Authors.Journal compilation John Wiley & Sons A/S. Objectives: Previous studies clinical samples (BD) suggest that there is increased prevalence and associated greater BD severity. We therefore examined this topic a representative epidemiologic sample. Methods: 2001–2002 National Epidemiologic Survey on...
<h3>Importance</h3> Early identification of individuals at high risk for the onset bipolar spectrum disorder (BPSD) is key from both a clinical and research perspective. While previous work has identified presence prodrome, predictive implications individual have not been assessed, to date. <h3>Objective</h3> To build calculator predict 5-year BPSD in youth familial BPSD. <h3>Design, Setting, Participants</h3> The Pittsburgh Bipolar Offspring Study an ongoing community-based longitudinal...
Self-harm behaviors, including suicidal ideation and past suicide attempts, are frequent in bariatric surgery candidates. It is unclear, however, whether these behaviors mitigated or aggravated by surgery.To compare the risk of self-harm before after surgery.In this population-based, self-matched, longitudinal cohort analysis, we studied 8815 adults from Ontario, Canada, who underwent between April 1, 2006, March 31, 2011. Follow-up for each patient was 3 years prior to surgery.Self-harm...
The authors evaluated lifetime prevalence and specificity of DSM-IV psychiatric disorders severity depressive manic symptoms at intake in preschool offspring parents with bipolar I II disorders.A total 121 ages 2-5 years from 83 disorder 102 65 demographically matched comparison (29 non-bipolar 36 without any psychopathology) were recruited for the study. Parents through advertisements adult outpatient clinics, ascertained random community. Participants standardized instruments. All staff...