A5090221397- Diabetes Management and Research
- Diabetes and associated disorders
- Pancreatic function and diabetes
- Diabetes Treatment and Management
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Diabetes Management and Education
- Chronic Kidney Disease and Diabetes
- Cardiovascular Function and Risk Factors
- Marriage and Sexual Relationships
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Mobile Health and mHealth Applications
- Diet and metabolism studies
- Adolescent and Pediatric Healthcare
- Obesity, Physical Activity, Diet
- Childhood Cancer Survivors' Quality of Life
- Chronic Disease Management Strategies
- Blood Pressure and Hypertension Studies
- Dialysis and Renal Disease Management
- Liver Disease Diagnosis and Treatment
- Health and Lifestyle Studies
- Diet, Metabolism, and Disease
- Gout, Hyperuricemia, Uric Acid
- Adipokines, Inflammation, and Metabolic Diseases
- Telemedicine and Telehealth Implementation
- Alcohol Consumption and Health Effects
Stanford University
2016-2025
Stanford Medicine
2016-2024
Lucile Packard Children's Hospital
2017-2024
University of Fort Lauderdale
2024
Orlando Health
2024
Wittenberg University
2024
The University of Adelaide
2024
University of Bari Aldo Moro
2024
Hospital General Universitario de Elche
2024
Semnan University of Medical Sciences
2024
Objective: To provide a snapshot of the profile adults and youth with type 1 diabetes (T1D) in United States assessment longitudinal changes T1D management clinical outcomes Exchange registry. Research Design Methods: Data on from 22,697 registry participants (age 1–93 years) were collected between 2016 2018 compared data 2010–2012 for 25,529 participants. Results: Mean HbA1c 2016–2018 increased 65 mmol/mol at age 5 years to 78 ages 15 18, decrease 64 by 28 58–63 beyond 30. The American...
To examine the overall state of metabolic control and current use advanced diabetes technologies in U.S., we report recent data collected on individuals with type 1 participating T1D Exchange clinic registry. Data from 16,061 participants updated between September 2013 December 2014 were compared registry enrollment 2010 to August 2012. Mean hemoglobin A1c (HbA1c) was assessed by year age <4 >75 years. The average HbA1c 8.2% (66 mmol/mol) at 8.4% (68 most update. During...
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To assess the proportion of youth with type 1 diabetes under care pediatric endocrinologists in United States meeting targets for HbA1c, blood pressure (BP), BMI, and lipids.Data were evaluated 13,316 participants T1D Exchange clinic registry younger than 20 years old ≥1 year.American Diabetes Association HbA1c <8.5% those 6 years, <8.0% to 13 old, <7.5% met by 64, 43, 21% participants, respectively. The majority BP lipids, two-thirds BMI goal <85th percentile.Most children have values above...
Few studies have assessed factors associated with severe hypoglycemia (SH) and diabetic ketoacidosis (DKA) in adults type 1 diabetes (T1D).Our objective was to determine frequency of the occurrence SH DKA T1D.We conducted a cross-sectional analysis from T1D Exchange clinic registry at 70 U.S. endocrinology centers.Analysis included 7012 participants aged 26 93 years old for ≥2 years.Higher frequencies were lower socioeconomic status (P < .001). strongly duration .001), 18.6% those ≥40 having...
OBJECTIVE To assess the frequency of continuous glucose monitoring (CGM) device use, factors associated with its and relationship CGM diabetes outcomes (HbA1c, severe hypoglycemia [SH], diabetic ketoacidosis [DKA]). RESEARCH DESIGN AND METHODS Survey questions related to use 1 year after enrollment in T1D Exchange clinic registry were completed by 17,317 participants. Participants defined as users if they indicated using real-time during prior 30 days. RESULTS Nine percent participants used...
Higher serum urate levels are associated with an increased risk of diabetic kidney disease. Lowering the level allopurinol may slow decrease in glomerular filtration rate (GFR) persons type 1 diabetes and early-to-moderate disease.In a double-blind trial, we randomly assigned participants diabetes, at least 4.5 mg per deciliter, estimated GFR 40.0 to 99.9 ml minute 1.73 m2 body-surface area, evidence disease receive or placebo. The primary outcome was baseline-adjusted GFR, as measured...
Abstract The significant and growing global prevalence of diabetes continues to challenge people with (PwD), healthcare providers, payers. While maintaining near-normal glucose levels has been shown prevent or delay the progression long-term complications diabetes, a proportion PwD are not attaining their glycemic goals. During past 6 years, we have seen tremendous advances in automated insulin delivery (AID) technologies. Numerous randomized controlled trials real-world studies that use AID...
Progressive CKD is generally detected at a late stage by sustained decline in eGFR and/or the presence of significant albuminuria. With aim early and improved risk stratification patients with CKD, we studied urinary peptides large cross-sectional multicenter cohort 1990 individuals, including 522 follow-up data, using proteome analysis. We validated that previously established multipeptide biomarker classifier performed significantly better detecting predicting progression than current...
As diabetes technology use in youth increases worldwide, inequalities access may exacerbate disparities hemoglobin A
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Background To assess the change in rates of pediatric real-time or intermittent scanning continuous glucose monitoring (CGM) use over past 5 years, and how it impacts glycemic control, data from two registries were compared: US-based type 1 diabetes Exchange Registry (T1DX) German/Austrian DPV (Prospective Diabetes Follow-Up Registry). Methods participants aged <18 years with T1D duration ≥1 year encompassed 29 007 individuals 2011 150 2016. Demographic data, CGM hemoglobin A1c (HbA1c)...
Hemoglobin A1c (HbA1c) levels among individuals with type 1 diabetes (T1D) influence the longitudinal risk for diabetes-related complications. Few studies have examined HbA1c trends across time in children, adolescents, and young adults T1D. This study examines changes glycemic control specific transition periods of pre-adolescence-to-adolescence adolescence-to-young adulthood, demographic clinical factors associated these changes.Available lab results up to 10 yr were collected from medical...
OBJECTIVE Diabetic ketoacidosis (DKA) in children and adolescents with established type 1 diabetes is a major problem considerable morbidity, mortality, associated costs to patients, families, health care systems. We analyzed data from three multinational registries/audits similarly advanced, yet differing, systems an aim identify factors DKA admissions. RESEARCH DESIGN AND METHODS Data 49,859 individuals &lt;18 years duration ≥1 year the Prospective Diabetes Follow-up Registry (DPV)...