Amisha Wallia

ORCID: 0000-0002-3183-4062
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About
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Research Areas
  • Diabetes Management and Research
  • Diabetes Treatment and Management
  • Hyperglycemia and glycemic control in critically ill and hospitalized patients
  • Diabetes and associated disorders
  • Metabolism, Diabetes, and Cancer
  • Diabetes Management and Education
  • Pharmaceutical Practices and Patient Outcomes
  • Pancreatic function and diabetes
  • Retinal Diseases and Treatments
  • Medication Adherence and Compliance
  • Retinal Imaging and Analysis
  • Chronic Disease Management Strategies
  • Pharmacology and Obesity Treatment
  • COVID-19 and Mental Health
  • Renal Transplantation Outcomes and Treatments
  • COVID-19 Clinical Research Studies
  • Transplantation: Methods and Outcomes
  • Liver Disease Diagnosis and Treatment
  • SARS-CoV-2 and COVID-19 Research
  • Gestational Diabetes Research and Management
  • Diet and metabolism studies
  • Healthcare professionals’ stress and burnout
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Nutrition and Health in Aging
  • Heart Rate Variability and Autonomic Control

Northwestern University
2015-2024

Evanston Hospital
2024

Prevention Group
2022

Massachusetts General Hospital
2022

Vanderbilt University Medical Center
2022

George Washington University
2022

Washington Center
2022

National Institutes of Health
2022

Northwestern University
2022

Lake Forest College
2021

Higher serum urate levels are associated with an increased risk of diabetic kidney disease. Lowering the level allopurinol may slow decrease in glomerular filtration rate (GFR) persons type 1 diabetes and early-to-moderate disease.In a double-blind trial, we randomly assigned participants diabetes, at least 4.5 mg per deciliter, estimated GFR 40.0 to 99.9 ml minute 1.73 m2 body-surface area, evidence disease receive or placebo. The primary outcome was baseline-adjusted GFR, as measured...

10.1056/nejmoa1916624 article EN New England Journal of Medicine 2020-06-24
David C. Klonoff Jing Wang David Rodbard Michael A. Kohn Chengdong Li and 89 more Dorian Liepmann David Kerr David Ahn Anne L. Peters Guillermo E. Umpierrez Jane Jeffrie Seley Nicole Y. Xu Kevin T. Nguyen Gregg D. Simonson Michael S. D. Agus Mohammed E. Al‐Sofiani Gustavo Armaiz-Peña Timothy S. Bailey Ananda Basu Tadej Battelino Sewagegn Yeshiwas Pierre‐Yves Benhamou B. Wayne Bequette Thomas Blevins Marc D. Breton Jessica R. Castle J. Geoffrey Chase Kong Y. Chen Pratik Choudhary Mark A. Clements Kelly L. Close Curtiss B. Cook Thomas Danne Francis J. Doyle Angela Drincic Kathleen Dungan Steven V. Edelman Niels Ejskjær Juan Espinoza G. Alexander Fleming Gregory P. Forlenza Guido Freckmann Rodolfo J. Galindo Ana María Gómez Hanna A. Gutow Lutz Heinemann Irl B. Hirsch Thanh D. Hoang Roman Hovorka Johan Jendle Linong Ji Shashank Joshi Michaël Joubert Suneil K. Koliwad Rayhan A. Lal M. Cecilia Lansang Wei-An Lee Lalantha Leelarathna Lawrence A. Leiter Marcus Lind Michelle L. Litchman Julia K. Mader Katherine Mahoney Boris Mankovsky Umesh Masharani Nestoras Mathioudakis Alexander Yur'evich Mayorov Jordan Messler Joshua D. Miller Viswanathan Mohan James H. Nichols Kirsten Nørgaard David N. O’Neal Francisco J. Pasquel Athena Philis‐Tsimikas Thomas R. Pieber Moshe Phillip William H. Polonsky Rodica Pop‐Busui Gerry Rayman Eun‐Jung Rhee Steven Russell Viral N. Shah Jennifer L. Sherr Koji Sode Elias K. Spanakis Deborah J. Wake Kayo Waki Amisha Wallia Melissa E. Weinberg Howard Wolpert Eugene E. Wright Mihail Zilbermint Boris Kovatchev

Background: A composite metric for the quality of glycemia from continuous glucose monitor (CGM) tracings could be useful assisting with basic clinical interpretation CGM data. Methods: We assembled a data set 14-day 225 insulin-treated adults diabetes. Using balanced incomplete block design, 330 clinicians who were highly experienced analysis and ranked best to worst glycemia. used principal component multiple regressions develop model predict clinician ranking based on seven standard...

10.1177/19322968221085273 article EN Journal of Diabetes Science and Technology 2022-03-29

OBJECTIVE The Diabetes Control and Complications Trial (DCCT) demonstrated that intensive therapy reduced the development progression of retinopathy in type 1 diabetes (T1D) compared with conventional therapy. Epidemiology Interventions (EDIC) study observational follow-up showed persistent benefits. In addition to glycemia, we now examine other potential risk factors (modifiable nonmodifiable) over more than 30 years DCCT/EDIC. RESEARCH DESIGN AND METHODS outcomes were proliferative...

10.2337/dc18-2308 article EN Diabetes Care 2019-03-04

In June 2016, Diabetes Technology Society convened a panel of US experts in inpatient diabetes management to discuss the current and potential role continuous glucose monitoring (CGM) hospital. This discussion combined with literature review was follow-up meeting, which took place May 2015. The reviewed evidence on use CGM 3 scenarios: (1) intensive care unit (ICU), (2) non-ICU, (3) transitioning outpatient into hospital setting. Panel members agreed that data from limited studies...

10.1177/1932296817706151 article EN Journal of Diabetes Science and Technology 2017-04-21
Eric D. Foster Nancy D. Bridges Irene D. Feurer Thomas L. Eggerman Lawrence G. Hunsicker and 95 more Rodolfo Alejandro Beth Begley Jose Cano Sallie Carpentier Jennifer Hutchinson Christian P. Larsen Johanna Moreno Marti H. Sears Nicole A. Turgeon Dasia Webster James F. Markmann Patrice Al‐Saden Xioajuan Chen Angela Hecyk Xunrong Luo Mark E. Molitch Natalie Monson Elyse Stuart Amisha Wallia Ling‐Jia Wang Shusen Wang Xiaomin Zhang Christine W. Czarniecki Julia Goldstein Allison Priore Mark A. Robien Elizabeth M. Schneider Guillermo Arreaza-Rubín Neal Green David L. Bigam Patricia Campbell Parastoo Dinyari Tatsuya Kin Norman M. Kneteman James Lyon Andrew J. Malcolm Doug O’Gorman Chris Onderka Richard Owen Rena Pawlick Brad Richer Shawn Rosichuk Donna Sarman Adam Schroeder Peter Senior A. M. James Shapiro Lana Toth Vali Toth Wendy Zhai Kristina Johnson Joan McElroy Andrew M. Posselt Marissa Ramos Tara Rojas Peter G. Stock Gregory L. Szot Barbara Barbaro Joan Martellotto José Oberholzer Meirigeng Qi Yong Wang Levent Bayman Kathryn Chaloner William R. Clarke Joseph S. Dillon Cynthia Diltz Gregory C. Doelle Dixie Ecklund Deb Feddersen Carol Jasperson David-Erick Lafontant Tina Neill-Hudson Deb Nollen Julie C. Qidwai Holly Riss Traci Schwieger Jamie Willits Jon Yankey Andrea Curry Corrales Raquel N. Faradji Tatiana Froud Ana Alvarez Gil Eva Herrada Luca Inverardi Norma S. Kenyon Aisha Khan Elina Linetsky Eduardo Peixoto Camillo Ricordi Muhamad H. Abdulla Appakalai N. Balamurugan Melena D. Bellin Mary Brandenburg James V. Harmon Bernhard J. Hering

Attaining glycemic targets without severe hypoglycemic events (SHEs) is a challenging treatment goal for patients with type 1 diabetes complicated by impaired awareness of hypoglycemia (IAH). The CIT Consortium Protocol 07 (CIT-07) trial showed islet transplantation to be an effective subjects IAH and intractable SHEs. We evaluated health-related quality life (HRQOL), functional health status, utility before after pancreatic in CIT-07 participants.Four surveys, the Diabetes Distress Scale...

10.2337/dc17-1779 article EN Diabetes Care 2018-03-21

This article is the work product of Continuous Glucose Monitor and Automated Insulin Dosing Systems in Hospital Consensus Guideline Panel, which was organized by Diabetes Technology Society met virtually on April 23, 2020. The guideline panel consisted 24 international experts use continuous glucose monitors (CGMs) automated insulin dosing (AID) systems representing adult endocrinology, pediatric obstetrics gynecology, advanced practice nursing, diabetes care education, clinical chemistry,...

10.1177/1932296820954163 article EN Journal of Diabetes Science and Technology 2020-09-28

<h3>Importance</h3> Understanding cardiovascular outcomes of initiating second-line antidiabetic medications (ADMs) may help inform treatment decisions after metformin alone is not sufficient or tolerated. To date, no studies have compared the effects all major ADMs during this early decision point in pharmacologic management type 2 diabetes. <h3>Objective</h3> examine association ADM classes with adverse events. <h3>Design, Setting, and Participants</h3> Retrospective cohort study among 132...

10.1001/jamanetworkopen.2018.6125 article EN cc-by-nc-nd JAMA Network Open 2018-12-21

The Diabetes Control and Complications Trial (DCCT) its observational follow-up Epidemiology of Interventions (EDIC) demonstrated the dominant role glycemia, second only to age, as a risk factor for first cardiovascular event in type 1 diabetes (T1D). We now investigate association between established factors total disease (CVD) burden, including subsequent (i.e., recurrent) events.CVD events 1,441 DCCT/EDIC participants were analyzed separately by (CVD death, acute myocardial infarction...

10.2337/dc19-2292 article EN Diabetes Care 2020-01-30

The HERO registry was established to support research on the impact of COVID-19 pandemic US healthcare workers. Describe experiences and effects individuals participating in registry. Cross-sectional, self-administered enrollment survey conducted from April 10 July 31, 2020. Participants worked hospitals (74.4%), outpatient clinics (7.4%), other settings (18.2%) located throughout nation. A total 14,600 exposure, viral antibody testing, diagnosis COVID-19, job burnout, physical emotional...

10.1007/s11606-020-06529-z article EN other-oa Journal of General Internal Medicine 2021-03-10
Christine G. Lee Brandy M. Heckman‐Stoddard Dana Dabelea Kishore M. Gadde David A. Ehrmann and 95 more Leslie Ford Philip C. Prorok Edward J. Boyko F. Xavier Pi‐Sunyer Amisha Wallia William C. Knowler Jill P. Crandall Marinella Temprosa George A. Bray Kishore M. Gadde Iris W. Culbert Jennifer Arceneaux Annie Chatellier Amber Dragg Catherine M. Champagne Crystal Duncan Barbara Eberhardt Frank L. Greenway Fonda G. Guillory April A. Herbert Michael L. Jeffirs Betty M. Kennedy Erma Levy Monica Lockett Jennifer C. Lovejoy Laura H. Morris Lee E. Melancon Donna H. Ryan Deborah A. Sanford Kenneth G. C. Smith Lisa L. Smith Julia A. St. Amant Richard T. Tulley Paula C. Vicknair Donald Williamson J. J. Zachwieja Kenneth S. Polonsky Janet Tobian David A. Ehrmann Margaret J. Matulik Karla A. Temple Bart Clark Kirsten Czech Catherine DeSandre Brittnie Dotson Ruthanne Hilbrich Wylie McNabb Ann R. Semenske F. José Kevin Furlong Barry J. Goldstein Pamela G. Watson Kellie A. Smith Jewel Mendoza Marsha Simmons Wendi Wildman Renee Liberoni John Spandorfer Constance Pepe Richard P. Donahue Ronald Goldberg Ronald J. Prineas Jeanette Calles Anna Giannella Patricia M. Rowe Juliet Sanguily Paul Cassanova-Romero Sumaya Castillo-Florez Hermes Flórez Rajesh Garg Lascelles Kirby Olga Lara Carmen Larreal Valerie McLymont Jadell Mendez Arlette C. Perry Patrice G. Saab Bertha Veciana Steven M. Haffner Helen P. Hazuda Maria G. Montez Kathy Hattaway Juan Isaac Carlos Lorenzo Arlene Martinez Monica Salazar Tatiana Walker Dana Dabelea Richard F. Hamman Patricia V. Nash Sheila C. Steinke Lisa Testaverde Jennifer Truong Denise Anderson Larry B. Ballonoff

OBJECTIVE To determine whether metformin or lifestyle modification can lower rates of all-cause and cause-specific mortality in the Diabetes Prevention Program Outcomes Study. RESEARCH DESIGN AND METHODS From 1996 to 1999, 3,234 adults at high risk for type 2 diabetes were randomized an intensive intervention, masked metformin, placebo. Placebo interventions stopped 2001, a modified program was offered everyone, but unmasked study continued those originally randomized. Causes deaths through...

10.2337/dc21-1046 article EN Diabetes Care 2021-10-25

A portion of patients with diabetes are repeatedly hospitalized for diabetic ketoacidosis (DKA), termed recurrent DKA, which is associated poorer clinical outcomes. This study evaluated fragmentation care, and mortality throughout six institutions in the Chicago area.A deidentified Health Insurance Portability Accountability Act-compliant data set from (HealthLNK) was used to identify 3,615 DKA (ICD-9 250.1x) 2006 2012, representing 5,591 inpatient admissions DKA. Demographic were queried....

10.2337/dc16-0668 article EN Diabetes Care 2016-07-15

Identifying factors associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection among health care workers (HCWs) may help systems optimize SARS-CoV-2 control strategies.We conducted a cross-sectional analysis of baseline data from the Northwestern HCW Serology Cohort Study. We used Abbott Architect Nucleocapsid IgG assay to determine seropositivity. Logistic regression models (adjusted for demographics and self-reported community exposure disease 2019 [COVID-19])...

10.1093/ofid/ofaa582 article EN cc-by-nc-nd Open Forum Infectious Diseases 2020-12-09

The annual Virtual Hospital Diabetes Meeting was hosted by the Technology Society on April 14 and 15, 2023, with goal of reviewing progress made in hospital use continuous glucose monitors (CGMs). topics included (1) Nursing Issues, Protocols, Order Sets, Staff Education for Using CGMs, (2) Implementing CGM Programs Use Wards, (3) Quality Metrics Financial Implications CGMs Hospital, (4) Critical Care Setting, (5) Special Situations: Labor/Delivery Hemodialysis, (6) Research Session (7)...

10.1177/19322968231186575 article EN Journal of Diabetes Science and Technology 2023-08-09

Intensive glycemic control has been shown to positively impact outcomes in an intensive care setting. Whether this practice is beneficial after liver transplantation (LT) not known.A retrospective review of patients undergoing LT from February 2002 July 2007 was conducted analyze the association between perioperative hyperglycemia and LT. Covariates included preexisting diabetes, mean glucose 3 months pre-LT, need for insulin drip post-LT, total during post-LT hospitalization, age, sex, type...

10.1097/tp.0b013e3181c3c2ff article EN Transplantation 2010-01-16
Maryam Afkarian Sarit Polsky Afshin Parsa Ronnie Aronson Maria Luiza Caramori and 95 more David Z.I. Cherney Jill P. Crandall Ian H. de Boer Thomas G. Elliott Andrzej T. Gałecki Allison B. Goldfine J. Sonya Haw Irl B. Hirsch Amy B. Karger Ildiko Lingvay David M. Maahs Janet B. McGill Mark E. Molitch Bruce A. Perkins Rodica Pop‐Busui Marlon Pragnell Sylvia E. Rosas Peter Rossing Peter Senior Ronald J. Sigal Cathie Spino Katherine R. Tuttle Guillermo E. Umpierrez Amisha Wallia Ruth S. Weinstock Chun-Yi Wu Michael Mauer Alessandro Doria Alessandro Doria Michael Mauer Ronnie Aronson Maria Luiza Caramori Jill P. Crandall Ian H. de Boer Alessandro Doria John H. Eckfeldt Thomas G. Elliott Michael F. Flessner Andrzej T. Gałecki Allison B. Goldfine Irl B. Hirsch Amy B. Karger Ildiko Lingvay David M. Maahs Michael Mauer Janet B. McGill Mark E. Molitch Helen Nickerson Afshin Parsa Bruce A. Perkins Sarit Polsky Rodica Pop‐Busui Marlon Pragnell Sylvia E. Rosas Peter Rossing Peter Senior Ronald J. Sigal Cathie Spino Katherine R. Tuttle Guillermo E. Umpierrez Andrzej T. Gałecki Massimo Pietropaolo Cathie Spino Yi‐Miau Tsai Chun-Yi Wu John H. Eckfeldt Amy B. Karger William N. Robiner Michael F. Flessner Afshin Parsa Helen Nickerson Marlon Pragnell Alessandro Doria Allison B. Goldfine Sylvia E. Rosas Enrico Cagliero Michael A Thompson Ruth S. Weinstock Christina Gjerlev-Poulsen Maria Lajer Frederik Persson Sascha Pilemann-Lyberg Peter Rossing Maria Luiza Caramori Michael Mauer Mary Frohauer San Thida Peter A. Gottlieb David M. Maahs Sarit Polsky Viral N. Shah Emily B. Schroeder Michael McDermott Lynn Ang Frank C. Brosius

Higher serum uric acid (SUA) is associated with diabetic kidney disease (DKD). Preventing Early Renal Loss in Diabetes (PERL) evaluates whether lowering SUA allopurinol slows glomerular filtration rate (GFR) loss people type 1 diabetes (T1D) and mild to moderate DKD. We present the PERL rationale, design, baseline characteristics.This double-blind, placebo-controlled, multicenter trial randomized 530 participants T1D, estimated GFR (eGFR) of 40-99.9 mL/min/1.73 m2, ≥4.5 m/dL, micro-...

10.2337/dc19-0342 article EN Diabetes Care 2019-06-11

This article is the work product of Continuous Ketone Monitoring Consensus Panel, which was organized by Diabetes Technology Society and met virtually on April 20, 2021. The panel consisted 20 US-based experts in use diabetes technology, representing adult endocrinology, pediatric advanced practice nursing, care education, clinical chemistry, bioengineering. panelists were from universities, hospitals, freestanding research institutes, government, private practice. Panelists reviewed medical...

10.1177/19322968211042656 article EN cc-by Journal of Diabetes Science and Technology 2021-10-04

To describe changes in antidiabetic medication (ADM) use and characteristics associated with ADM after initiation of noninsulin second-line therapy.

10.37765/ajmc.2023.89466 article EN The American Journal of Managed Care 2023-12-01

Older people with HIV (OPWH) have an increased risk of type 2 diabetes mellitus (T2DM). Understanding this is important to screen and initiate treatments. This study explored awareness T2DM, perceived risk, willingness receive T2DM preventive education. OPWH were recruited from academic health center in Chicago, Illinois between November 2022 January 2023. Staff used interview guides for qualitative data collection administered a sociodemographic survey. Qualitative was analyzed using the...

10.1080/09540121.2025.2474667 article EN AIDS Care 2025-03-11

Abstract Objective: To determine the changes in severe acute respiratory coronavirus virus 2 (SARS-CoV-2) serologic status and SARS-CoV-2 infection rates healthcare workers (HCWs) over 6-months of follow-up. Design: Prospective cohort study. Setting participants: HCWs Chicago area. Methods: Cohort participants were recruited May June 2020 for baseline serology testing (Abbott anti-nucleocapsid IgG) then invited follow-up 6 months later. Participants completed monthly online surveys that...

10.1017/ice.2021.367 article EN Infection Control and Hospital Epidemiology 2021-08-09
Michael R. Rickels Thomas L. Eggerman Levent Bayman Julie C. Qidwai Rodolfo Alejandro and 95 more Nancy D. Bridges Bernhard J. Hering James F. Markmann Peter Senior Lawrence G. Hunsicker José G. Ávila Beth Begley Jose Cano Sallie Carpentier Elizabeth Holbrook Jennifer Hutchinson Christian P. Larsen Johanna Moreno Marti H. Sears Nicole A. Turgeon Dasia Webster Christian Berne Carl Jorns Torbjörn Lundgren Mikael Rydén Enrico Cagliero Kerry Crisalli Shan Deng Ji Lei James F. Markmann David M. Nathan Patrice Al‐Saden J. Battle Xioajuan Chen Angela Hecyk Dixon B. Kaufman H Kißler Xunrong Luo Mark E. Molitch Natalie Monson Elyse Stuart Amisha Wallia Ling‐Jia Wang Shusen Wang Xiaomin Zhang Nancy D. Bridges Christine W. Czarniecki Julia Goldstein Tomeka Granderson Yvonne Morrison Allison Priore Gerry Putz Mark A. Robien Elizabeth M. Schneider Guillermo Arreaza Thomas L. Eggerman Neal Green David L. Bigam Patricia Campbell Parastoo Dinyari Sharleen Imes Tatsuya Kin Norman M. Kneteman Angela Koh James Lyon Andrew J. Malcolm Doug O’Gorman Chris Onderka Richard Owen Rena Pawlick Brad Richer Shawn Rosichuk Edmond A. Ryan Donna Sarman Adam Schroeder Peter Senior A. M. James Shapiro Lana Toth Vali Toth Wendy Zhai Kristina M. Johnson Joan McElroy Andrew M. Posselt Marissa Ramos Tara Rojas Peter G. Stock Gregory L. Szot Barbara Barbaro Leelama George Joan Martellotto José Oberholzer Meirigeng Qi Yong Wang Levent Bayman Kathryn Chaloner William R. Clarke Joseph S. Dillon Cynthia Diltz Gregory C. Doelle Dixie Ecklund

OBJECTIVE To determine long-term outcomes for islet-alone and islet-after-kidney transplantation in adults with type 1 diabetes complicated by impaired awareness of hypoglycemia. RESEARCH DESIGN AND METHODS This was a prospective interventional observational cohort study (n = 48) 24) transplant recipients followed up to 8 years after intraportal infusion one or more purified human pancreatic islet products under standardized immunosuppression. Outcomes included duration graft survival...

10.2337/dc21-2688 article EN Diabetes Care 2022-10-17

Introduction During the coronavirus disease 2019 pandemic, high levels of burnout were reported among healthcare workers. This study examines association work absenteeism and frequency thoughts in leaving current job with a cohort workers during COVID-19 pandemic. Methods A cross-sectional survey was conducted from April-May, 2022 on 10 hospitals, 18 immediate care centers, 325 outpatient practices Chicago area surrounding Illinois suburbs. Logistic regression models used to assess scores...

10.3389/frhs.2023.1272285 article EN cc-by Frontiers in Health Services 2023-11-29
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