A5011991205- Diabetes Management and Research
- Pancreatic function and diabetes
- Diabetes and associated disorders
- Diabetes Treatment and Management
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Gestational Diabetes Research and Management
- Diet and metabolism studies
- Diabetes Management and Education
- Chronic Disease Management Strategies
- Chronic Kidney Disease and Diabetes
- Metabolism, Diabetes, and Cancer
- Birth, Development, and Health
- Diet, Metabolism, and Disease
- Cardiovascular Function and Risk Factors
- Epigenetics and DNA Methylation
- Pharmacology and Obesity Treatment
- Heart Rate Variability and Autonomic Control
- Retinal Diseases and Treatments
- Obesity, Physical Activity, Diet
- Blood Pressure and Hypertension Studies
- Liver Disease Diagnosis and Treatment
- Cardiovascular Syncope and Autonomic Disorders
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Control Systems and Identification
- Bariatric Surgery and Outcomes
University of Copenhagen
2015-2025
Steno Diabetes Centers
1993-2025
Copenhagen University Hospital
2016-2025
The University of Adelaide
2024
University of Bari Aldo Moro
2024
Hospital General Universitario de Elche
2024
Semnan University of Medical Sciences
2024
Cornell University
2024
University of Virginia
2024
Danish Diabetes Association
2021-2024
Abstract The significant and growing global prevalence of diabetes continues to challenge people with (PwD), healthcare providers, payers. While maintaining near-normal glucose levels has been shown prevent or delay the progression long-term complications diabetes, a proportion PwD are not attaining their glycemic goals. During past 6 years, we have seen tremendous advances in automated insulin delivery (AID) technologies. Numerous randomized controlled trials real-world studies that use AID...
Background: A composite metric for the quality of glycemia from continuous glucose monitor (CGM) tracings could be useful assisting with basic clinical interpretation CGM data. Methods: We assembled a data set 14-day 225 insulin-treated adults diabetes. Using balanced incomplete block design, 330 clinicians who were highly experienced analysis and ranked best to worst glycemia. used principal component multiple regressions develop model predict clinician ranking based on seven standard...
Comparing the performance of different continuous glucose monitoring (CGM) systems is challenging due to lack comprehensive guidelines for clinical study design. In particular, absence concise requirements distribution comparator (reference) blood (BG) concentrations and their rate change (RoC) that are used evaluate CGM performance, impairs comparability. For this article, several experts in field testing have collaborated propose characteristics measurements should be collected during...
OBJECTIVE: Impairment of left ventricular diastolic function, possibly caused by increased collagen cross-linking the cardiac muscle, is common in patients with type 1 diabetes even without coronary artery disease. Advanced glycation end products (AGEs) cross-link tissue and are found within myocardial fibers. The aim this study was to examine for a possible association between circulating AGEs function. RESEARCH DESIGN AND METHODS: Left systolic function were assessed M-mode Doppler...
The St Vincent Declaration, a joint initiative on diabetes care and research of the World Health Organization (Europe) International Diabetes Federation (Europe), includes 5-year targets for improvement in outcomes as central tenet. Accordingly, establishment state art monitoring control systems is urged basis implementation quality management. As prerequisite both targets, dataset (fields definitions) has been agreed to allow common throughout Europe. This further developed foundation stone...
To investigate the efficacy of sensor-augmented pump therapy vs. multiple daily injection in patients with suboptimally controlled Type 1 diabetes.In this investigator-initiated multi-centre trial (the Eurythmics Trial) eight outpatient centres Europe, we randomized 83 diabetes (40 women) currently treated injections, age 18-65 years and HbA(1c) ≥ 8.2% (≥ 66 mmol/mol) to 26 weeks treatment either a insulin (n = 44) (Paradigm(®) REAL-Time) or continued injections 39). Change between baseline...
To investigate the effect of flexible intensive insulin therapy (FIIT) and an automated bolus calculator (ABC) in a Danish type 1 diabetes population treated with multiple daily injections. Furthermore, to test feasibility teaching FIIT 3-h structured course.The BolusCal Study was 16-week randomized, controlled, open-label, three-arm parallel, clinical study 51 adults diabetes. Patients aged 18-65 years poor metabolic control (HbA(1c) 8.0-10.5%) were randomized Control (n = 8), CarbCount...
Sensor-augmented pump (SAP) therapy can improve glycemic control, compared with multiple daily insulin injections or alone, without increasing the risk of hypoglycemia.
In diabetes prevention and care, invasiveness of glucose measurement impedes efficient therapy hampers the identification people at risk. Lack calibration stability in non-invasive technology has confined field to short-term proof principle. Addressing this challenge, we demonstrate first practical use a Raman-based portable monitoring device used for least 15 days following calibration. home-based clinical study involving 160 subjects with diabetes, largest its kind our knowledge, find that...
OBJECTIVE To compare the 12-month effects of continuous glucose monitoring (CGM) versus blood (BGM) in adults with insulin-treated type 2 diabetes. RESEARCH DESIGN AND METHODS This is a single-center, parallel, open-label, randomized controlled trial including inadequately controlled, diabetes from outpatient clinic at Steno Diabetes Center Copenhagen, Denmark. Inclusion criteria were ≥18 years age, diabetes, and HbA1c ≥7.5% (58 mmol/mol). Participants randomly assigned (1:1) to 12 months...
The physical and psychological benefits of exercise are particularly pertinent to people with type 1 diabetes (T1D). variability in subcutaneous insulin absorption the delay offset onset glucose lowering action impose limitations, given rapidly varying requirements exercise. Simultaneously, there challenges monitoring. Consequently, those T1D less likely because concerns regarding instability. While control can be enhanced using automated delivery (AID), all commercially available AID...
One-hundred and ten patients treated with lithium for more than six months were studied in order to determine the prevalence of induced nephropathy. Eighteen 69 (26 per cent) who had been two years presented a chronic interstitial nephropathy characterized by marked decrease renal concentrating ability disproportionate preservation glomerular filtration rate. Histologically, increased amounts fibrotic tissue medulla cortex found together tubular atrophy. In 40 cent underwent biopsy, cystic...