A5013623742- Diabetes Management and Research
- Diabetes and associated disorders
- Pancreatic function and diabetes
- Diabetes Treatment and Management
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Cystic Fibrosis Research Advances
- Mobile Health and mHealth Applications
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Neonatal Respiratory Health Research
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Pharmaceutical studies and practices
- Adolescent and Pediatric Healthcare
- Health and Medical Studies
- Cardiovascular and exercise physiology
- Bacterial Infections and Vaccines
- Wireless Body Area Networks
- ECG Monitoring and Analysis
- Spectroscopy Techniques in Biomedical and Chemical Research
- Bone health and osteoporosis research
- Pediatric Pain Management Techniques
- Time Series Analysis and Forecasting
- Chronic Disease Management Strategies
- COVID-19 Clinical Research Studies
- Intracranial Aneurysms: Treatment and Complications
- AI in cancer detection
University of Bonn
2011-2023
German Red Cross
2021
Krankenhaus vom Roten Kreuz
2021
University of Siegen
2020
St Clement's Hospital
2019
Zentrum für Kinderheilkunde
2018
University Hospital Bonn
2011
Eppendorf (Germany)
2011
OBJECTIVE To investigate temporal trends and contemporary use of insulin pump therapy glucose monitoring in type 1 diabetes. RESEARCH DESIGN AND METHODS In a population-based study, we analyzed the therapy, continuous (CGM), self-monitoring blood (SMBG) from 1995 to 2017 patients with diabetes identified Diabetes Prospective Follow-up (DPV) database Germany Austria. Patients were stratified by age, sex, migration background, country. RESULTS Among 96,547 (median age 17.9 years, 53% males),...
Physical exercise is an important component in the management of type 1 diabetes across lifespan. Yet, acute increases risk dysglycaemia, and direction glycaemic excursions depends, to some extent, on intensity duration exercise. Understandably, fear hypoglycaemia one strongest barriers incorporating into daily life. Risk during after can be lowered when insulin-dose adjustments are made and/or additional carbohydrates consumed. Glycaemic has been easier with continuous glucose monitoring...
Aim: Insulin pump, continuous glucose monitoring (CGM), and sensor augmented pump (SAP) technology have evolved continuously leading to the development of automated insulin delivery (AID) systems. Evaluation use diabetes technologies in people with T1D from January 2018 December 2021. Methods: A patient registry (Diabetes Prospective Follow-up Database [DPV]) was analyzed for SAP (insulin + CGM ≥90 days, no dose adjustment) AID (HCL or LGS/PLGS). In total 46,043 aged 0.5 <26 years treated...
Background . High-producer TGF β 1 genotypes are associated with severe lung disease in cystic fibrosis (CF), but studies combining IL-8, TNF α -, and 1(+genotype) levels their impact on CF scarce. Aim Assessing the relationship between 1, TNF- an exacerbation-free interval. Methods Twenty four patients delta F508 homozygous (median age 20.5 y, Shwachman score 75, FEV1(%) 83) 8 controls 27.5 y) were examined. was assessed serum induced sputum (IS) by ELISA, for IL-8 chemiluminescence IS...
Objective: Cerebral aneurysms of an infectious etiology, so-called "mycotic" aneurysms, are rare neurovascular pathologies. Primary treatment may be targeted on the aneurysm, but care has to driven by underlying pathology prevent often fatal clinical course with a mortality rate reaching 90%. 2 case reports presented, and diagnostic therapeutic issues outlined reviewing literature.
To describe the different insulin therapy patterns and daily doses in children adolescents (aged 1-17 years) with type 1 diabetes.This cross-sectional study based on longitudinal prescription (LRx) database (IQVIA) included who received at least two prescriptions of same drug from January 2016 to 31 December 2019. The outcomes proportion patients pumps multiple injection therapy, human analogue use, as well doses. A multivariable linear regression model was used association between age, sex,...
Abstract Aim To evaluate how many people with type 2 diabetes receive a treatment regimen insulin as first‐line therapy and the factors associated this. Methods This retrospective study was based on data from Disease Analyzer database included 10 497 an initial prescription of anti‐hyperglycaemic 859 general diabetologist practices in Germany between January 2014 December 2018. The main outcome prevalence therapy. A multivariable logistic regression model performed to investigate association...
The aim of this cross-sectional retrospective study was to estimate the prevalence different physical and psychiatric disorders as well multimorbidity in outpatients with type 1 diabetes (T1D) Germany.A total 6967 adult patients T1D from 958 general or diabetologist practices Germany between January 2015 December 2019 Disease Analyzer database (IQVIA) were included. main outcome diabetes-related nondiabetes-related within 12 months prior last outpatient visit. Multivariate logistic...
Glycemic targets are often difficult to achieve in people with type 1 diabetes, especially during exercise. Consequently, many diabetes avoid sports as a result of fear hypoglycemia. Strenuous physical activity, such half marathon, imposes difficulties on diabetes. The first commercial hybrid closed-loop (HCL) system the potential facilitate better management exercise has recently been marketed. So far, no data HCL performance strenuous have published. A woman well-controlled participated...
Abstract This case report demonstrates that using a non‐approved long‐acting GLP‐1‐RA (dulaglutide) in adolescents with T2D is possible and feasible under special circumstances when approved therapeutic options for the pediatric population fail to achieve adequate glycemic control.
Abstract Aim To compare the daily consumption of blood glucose test strips (BGTSs) prior to and after initiation intermittent‐scanning continuous monitoring (iscCGM). Methods This study included 1343 adults (≥18 years) with type 1 (T1D) or 2 diabetes (T2D; mean age 51.4 years; 39.1% women) from IMS Disease Analyzer database an initial prescription iscCGM in Germany between January 2015 July 2018 (index date). We compared average BGTS index date versus date. A multivariate logistic regression...
Hypoglycemia is a medical emergency characterized by low glucose levels (70 mg/dL or 3.9 mmol/L), which can be asymptomatic and difficult to predict in patients with type 1 diabetes (T1D). This study leverages the synergistic capabilities of advanced machine learning (ML) models integrates noninvasive heart rate continuous monitoring time onset hypoglycemia events. Unlike prior research, this extends prediction times customizes personalized for early detection hypoglycemia. In study, we...
During the last 20 years, use of insulin pump therapy in different age groups with type 1 diabetes (T1D) has been constantly increasing, a marked rise youngest groups.1 Several studies have analysed and its impact on metabolic control paediatric young adult population showed that patients treated had lower risk severe hypoglycaemia diabetic ketoacidosis, glycated haemoglobin (HbA1c) levels.2, 3 Previous shown female gender >10 as well high HbA1c level at beginning therapy, were associated...