A5069785394- Diabetes Management and Research
- Pancreatic function and diabetes
- Diabetes and associated disorders
- Diabetes Treatment and Management
- Adolescent and Pediatric Healthcare
- Childhood Cancer Survivors' Quality of Life
- Diabetes Management and Education
- Mobile Health and mHealth Applications
- Obesity, Physical Activity, Diet
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Chronic Kidney Disease and Diabetes
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diet and metabolism studies
- Chronic Disease Management Strategies
- Eating Disorders and Behaviors
- Family and Disability Support Research
- Blood Pressure and Hypertension Studies
- Diet, Metabolism, and Disease
- Health and Lifestyle Studies
- Renin-Angiotensin System Studies
- Gestational Diabetes Research and Management
- Metabolism, Diabetes, and Cancer
- Family Support in Illness
- Cardiovascular Function and Risk Factors
- Retinal Diseases and Treatments
Joslin Diabetes Center
2016-2025
Harvard University
2016-2025
Boston Children's Hospital
2013-2025
Hadassah Medical Center
2024
Boston Children's Museum
2024
Stanford Medicine
2024
Hershey (United States)
2024
Beth Israel Deaconess Medical Center
2023
Terra
2022
Valid International (United Kingdom)
2022
The value of continuous glucose monitoring in the management type 1 diabetes mellitus has not been determined.
Type 1 diabetes is characterized by an immune-mediated depletion of b-cells that results in lifelong dependence on exogenous insulin.While both type and 2 result hyperglycemia, the pathophysiology etiology diseases are distinct require us to consider each independently.As such, this position statement summarizes available data specific comprehensive care individuals with diabetes.The goal enhance our ability recognize manage diabetes, prevent its associated complications, eventually cure disease.
Closed-loop systems that automate insulin delivery may improve glycemic outcomes in patients with type 1 diabetes.
Only one third of patients with juvenile-onset insulin-dependent diabetes seem to be susceptible diabetic nephropathy. To test whether this susceptibility is related a predisposition hypertension, we investigated the association nephropathy markers risk for hypertension. We randomly selected 89 from roster children and adolescents who were seen between 1968 1972 at about time diagnosis was made. These recalled examination, as young adults, in 1986 1987. Patients (cases, n = 33) compared...
During childhood and adolescence, there is a gradual shift from diabetes care supervised by parents other adults to self-care management. The actual change pediatric adult health providers signals more abrupt that requires preparation patients, their families, providers. A number of publications the U.S. countries have highlighted substantial gaps in during this transition period between often arise later adolescence subsequent developmental stage life termed “emerging adulthood.” This...
The risk of microalbuminuria in patients with insulin-dependent diabetes mellitus (IDDM) is thought to depend on the degree hyperglycemia, but relation between hyperglycemia and urinary albumin excretion has not been defined.We measured three random urine samples obtained at least one month apart from 1613 IDDM. Microalbuminuria or overt albuminuria was considered be present if ratio (in micrograms) creatinine milligrams) 17 299 > = 300, respectively, for men 25 women. Measurements...
Table 1
OBJECTIVE: To design and evaluate an office-based intervention aimed at maintaining parent-adolescent teamwork in diabetes management tasks without increasing diabetes-related family conflict. RESEARCH DESIGN AND METHODS: There were 85 patients (aged 10-15 years, mean 12.6 years) with type 1 (mean duration 5.5 years; HbA1c 8.5%) who randomly assigned to one of three study groups--teamwork, attention control, standard care--and followed for 24 months. At each visit, parent involvement insulin...
Depression in children and adolescents with type 1 diabetes has been associated negative diabetes-related health outcomes such as poorer glycemic control (1–5) recurrent diabetic ketoacidosis (DKA) admissions (6,7). While mechanisms that link depression suboptimal are poorly understood (8), it is apparent the chronicity of demands management provide a fertile environment for adjustment problems. Our aim was to investigate depressive symptoms their association demographic, diabetes-specific,...
Adolescents and young adults with type 1 diabetes exhibit the worst glycemic control among individuals across lifespan. Although continuous glucose monitoring (CGM) has been shown to improve in adults, its benefit adolescents not demonstrated.To determine effect of CGM on diabetes.Randomized clinical trial conducted between January 2018 May 2019 at 14 endocrinology practices US including 153 aged 24 years screening hemoglobin A1c (HbA1c) 7.5% 10.9%.Participants were randomized 1:1 undergo...
To evaluate the safety and efficacy of empagliflozin 10- 25-mg doses plus a unique lower dose (2.5 mg) as adjunct to intensified insulin in patients with type 1 diabetes (T1D).The EASE (Empagliflozin Adjunctive inSulin thErapy) program (N = 1,707) included two double-blind, placebo-controlled phase 3 trials: EASE-2 10 mg (n 243), 25 244), placebo 52-week treatment; EASE-3 2.5 241), 248), 245), 26-week treatment. Together they evaluated mg, currently approved treatment 2 diabetes,...
Background: Cell phone text messaging, via the Short Messaging Service (SMS), offers promise of a highly portable, well-accepted, and inexpensive modality for engaging youth young adults in management their diabetes. This pilot feasibility study compared two-way SMS cell messaging with e-mail reminders that were directed at encouraging blood glucose (BG) monitoring. Methods: Forty insulin-treated adolescents diabetes randomized to receive electronic check BG levels or 3-month study....
Abstract The significant and growing global prevalence of diabetes continues to challenge people with (PwD), healthcare providers, payers. While maintaining near-normal glucose levels has been shown prevent or delay the progression long-term complications diabetes, a proportion PwD are not attaining their glycemic goals. During past 6 years, we have seen tremendous advances in automated insulin delivery (AID) technologies. Numerous randomized controlled trials real-world studies that use AID...
Advances in diabetes technology have transformed the treatment paradigm for type 1 diabetes, yet burden of disease is significant. We report on a pivotal safety study first tubeless, on-body automated insulin delivery system with customizable glycemic targets.This single-arm, multicenter, prospective enrolled 112 children (age 6-13.9 years) and 129 adults 14-70 years). A 2-week standard therapy phase (usual regimen) was followed by 3 months delivery. Primary outcomes were incidence severe...