- Angiogenesis and VEGF in Cancer
- Drug Transport and Resistance Mechanisms
- Proteoglycans and glycosaminoglycans research
- Stress Responses and Cortisol
- Antenna Design and Analysis
- ZnO doping and properties
- Sports Performance and Training
- Cancer, Hypoxia, and Metabolism
- Menstrual Health and Disorders
- Glycosylation and Glycoproteins Research
- Venous Thromboembolism Diagnosis and Management
- Nanoparticle-Based Drug Delivery
- Drug Solubulity and Delivery Systems
- Muscle metabolism and nutrition
- RNA Interference and Gene Delivery
- Prostate Cancer Treatment and Research
- Cell Adhesion Molecules Research
- Energy Harvesting in Wireless Networks
- Advanced Drug Delivery Systems
- Additive Manufacturing and 3D Printing Technologies
- 3D Printing in Biomedical Research
- Exercise and Physiological Responses
- GaN-based semiconductor devices and materials
- Microwave Engineering and Waveguides
- Hormonal Regulation and Hypertension
University of Utah
2024-2025
Rajshahi University of Engineering and Technology
2020-2023
Texas Tech University
2017-2022
Texas Tech University Health Sciences Center
2017-2022
Bangabandhu Sheikh Mujib Medical University
2021-2022
Presidency University
2021
University of Liverpool
2019
Clatterbridge Cancer Centre NHS Foundation Trust
2019
Seoul National University
2012-2017
Meharry Medical College
2012-2016
With technological advancement, photonic crystal fibers (PCFs) are effectively used to design miniaturized, flexible, and efficient biosensors. This paper proposes an exposed core PCF biosensor based on widely known surface plasmon resonance (SPR) phenomena. An external sensing mechanism is followed characterize the performance within refractive index (RI) range between 1.28 1.40. Metal strip (gold (Au) titanium dioxide (TiO 2 )) deposited outer only along four channels instead of entire...
Apical sodium-dependent bile acid transporters (ASBT) are the intestinal that form intermediate complexes with substrates and its conformational change drives movement of across cell membrane. However, membrane-based confined to transport only small molecular substrates. Here, we propose a new strategy uses high-affinity binding macromolecular functionally transform membrane so they behave like receptors, ultimately allowing apical-basal bound macromolecules. Bile based were synthesized...
This paper explores how the increasing demand for renewable energy sources has resulted in development of innovative technologies to harness solar and wind power. The evaluates potential hybrid power generation as a solution address reliability, cost, environmental sustainability challenges. presents system that generates electricity using power, wherein an external high-speed fan rotates rotor dynamo, producing magnetic flux creates DC voltage, panel absorbs photons light, creating another...
Incarceration affects the lives of many African American men and often leads to poverty, ill health, violence, a decreased quality life. There has been an unprecedented increase in incarceration among males since 1970. In 2009, rate black was 6.7 times that white 2.6 Hispanic males. Substance abuse higher mortality rates, high rates alcohol-related problems, more likely be victims crimes, HIV/AIDS. Americans comprised only 14% U.S. population but 38% jail population. The cost incarcerating...
Controlled and site-specific regulation of growth factor signaling remains a major challenge for current antiangiogenic therapies, as these agents target normal vasculature well tumor vasculature. In this article, we identified the prion-like protein doppel potential therapeutic angiogenesis. We investigated interactions between VEGFR2 evaluated whether blocking doppel/VEGFR2 axis suppresses process discovered that endothelial cells (TECs), but not ECs, express doppel; tumors from patients...
In our previous studies, taurocholic acid (TA)-conjugated low-molecular-weight heparin derivative (LHT7) has been proven to be a potent anti-angiogenic agent by demonstrated successful blockage capability of vascular endothelial growth factors (VEGF). Preliminary safety evaluations were conducted based on its mechanism action and chemical behavior. For this purpose, acute toxicity study, hematological serological carried out. Additionally, in order evaluate mechanism-related side effects,...
In recent years measles has been one of the most critical public health problem in Bangladesh. Although Ministry Health Bangladesh employs a broad extension control policies, logistical challenges exist, and there is significant doubt regarding disease burden. Mathematical modelling considered effective ways to understand infection transmission estimate parameters different countries, such as this study, mathematical framework presented explore dynamics We calibrated model using cumulative...
Modern technology advancement requires a more extensive data rate to convey information rapidly than ever. Improved bandwidth can satisfy the need for high-speed transmission demand. In order achieve significantly increased high communication, antenna design at THz band is essential. The microstrip patch one of most prominent antennas applications such future 5G communication systems and advanced wireless system. This paper proposed triangular where FR4 used substrate as an insulator...
As a class of angiogenesis inhibitors, heparin conjugates have shown significant effectiveness in several studies.The purpose our current study is to evaluate the and safety infusing conjugate low molecular weight taurocholate (LHT7), which has been developed as potent inhibitor.To its safety, method intravenous infusion was compared with i.v. bolus administration. Intravenous administered at rate 400 μl/min/kg body for 30 min. Pharmacokinetic (PK) analysis, organ accumulation, plasma...
To achieve a clinically rational regimen for cancer chemoprevention with improved efficacy and safety, the combination effect of celecoxib newly developed oral angiogenesis inhibitor, LHD4, on was evaluated. The chemopreventive effects celecoxib, LHD4 were evaluated in murine colorectal carcinogenesis model. After 17 experimental weeks, mouse colon tissues collected examined terms polyp volume degree carcinogenesis, inflammation, angiogenesis. Mice celecoxib-treated or LHD4-treated groups...
Depression is very common in reproductive women particularly with premenstrual dysphoric disorder (PMDD), which a severe form of syndrome (PMS). Beta-arrestins were previously implicated the pathophysiology, diagnosis and treatment for mood disorders. This study examined whether measurement beta-arrestin1 levels peripheral blood mononuclear leukocytes (PBMC), could aid to distinguish between PMDD PMS. Study participants (n = 25) non-pregnant 18–42 years age symptoms PMS/PMDD, but not taking...
Tumor-derived exosomes are bound and internalized to organ-specific cells, affecting metastasis. Heparan sulfate proteoglycans mediate the interaction between cells exosomes. Exosome transfer recipient cell can be competitively blocked by heparinoids, because heparin is structurally similar heparan sulfate. It hypothesized that there may structural requirements of heparinoids attenuate cellular uptake metastatic activity tumor-derived Here, we compared properties unfractionated (UFH),...