A5100778105- Essential Oils and Antimicrobial Activity
- Carcinogens and Genotoxicity Assessment
- Bee Products Chemical Analysis
- Phytochemicals and Antioxidant Activities
- Insect and Pesticide Research
- Plant biochemistry and biosynthesis
- Plant Physiology and Cultivation Studies
- Renal Transplantation Outcomes and Treatments
- Hepatitis C virus research
- Nuts composition and effects
- Radiation Dose and Imaging
- Cardiovascular Disease and Adiposity
- Antioxidant Activity and Oxidative Stress
- Advanced Radiotherapy Techniques
- Hepatitis B Virus Studies
- DNA and Nucleic Acid Chemistry
- Cardiac Imaging and Diagnostics
- Healthcare and Venom Research
- Pancreatitis Pathology and Treatment
- Diabetic Foot Ulcer Assessment and Management
- Botanical Studies and Applications
- Pain Management and Treatment
- Seed and Plant Biochemistry
- Phytochemicals and Medicinal Plants
- Weed Control and Herbicide Applications
Ardahan University
2014-2024
Inonu University
2022-2023
Turgut Özal Tıp Merkezi
2022-2023
Canakkale Onsekiz Mart Universitesi Tip Fakultesi Hastanesi
2022
State Hospital
2022
Pamukkale University
2021
Dicle University
2016
Cukurova University
2001-2013
In the present study, genotoxic effects of low-calorie sweetener aspartame (ASP), which is a dipeptide derivative, was investigated using chromosome aberration (CA) test, sister chromatid exchange (SCE) micronucleus test in human lymphocytes and also Ames/Salmonella/ microsome test. ASP induced CAs at all concentrations (500, 1000 2000 microg/ml) treatment periods (24 48 h) dose-dependently, while it did not induce SCEs. On other hand, decreased replication index (RI) only highest...
Despite its intended use, imidacloprid causes genotoxic and cytotoxic effects in mammals, especially the presence of metabolic activation systems. The aim this study was to determine which extent these are sex related how metabolism modulators piperonyl butoxide menadione affect toxicity. Male female Sprague-Dawley rats were injected with intraperitoneal LD50 dose alone (170 mg/kg) or pretreated (100 (25 for 12 24 h. Structural chromosome aberrations, abnormal cells mitotic index determined...
In the current study, biochemical components, antioxidant activity, antibacterial and antimutagenic activity of 5 plum (Demal, White Cancur, Red plum, Sugar plum) fruits grown in Posof/Ardahan, Turkey were investigated. While other genotypes are cultured, Demal genotype grows wild. The highest total ascorbic acid (TAC; 454 mg/100 g FW (fresh weight)) flavonoid content (TFC; 29.1 FW) detected genotype. Ferric Reducing Antioxidant Power (FRAP) 2,2ʹ-azino-bis 3-ethylbenzothiazoline-6-sulfonic...
Abstract Earlier research has evidenced the oxidative and neurotoxic potential of imidacloprid, a neonicotinoid insecticide, in different animal species. The primary aim this study was to determine how metabolic modulators piperonyl butoxide menadione affect imidacloprid’s adverse action liver kidney Sprague-Dawley rats both sexes. animals were exposed imidacloprid alone (170 mg kg-1) or combination with (100 (25 for 12 24 h. Their homogenates analysed spectrophotometrically glutathione...
Abstract The aim of this study was to compare the biological activities ethanolic propolis extracts Apis mellifera caucasica obtained from Ardahan and Erzurum provinces Turkey. Samples were tested for antioxidant, anticytotoxic, anticarcinogenic, antibacterial, antifungal potentials using different techniques. Propolis samples two had mineral organic compositions related their geographical origin. ferric reducing antioxidant power (FRAP) test showed superiority over Erzurum. Regardless...
Rhus coriaria has been important in the treatment of many diseases traditional use. In this content, genotoxic, antigenotoxic, and oxidative stress effects methanol extract R. (RCE) were investigated study. Two hundred fifty, 500, or 750 µg/mL concentrations RCE not found to have DNA damaging effect on pET22-b(+) plasmid unable induce micronuclei human lymphocytes (24 48 h period). However, it did inhibit genotoxic mitomycin-c (0.25 µg/mL). Cytotoxic using mitotic index (MI) nuclear division...
Macrolide antibiotic roxithromycin was evaluated in terms of its genotoxic, cytotoxic and oxidative stress effects. For this purpose; 25, 50, 100 200 μg/mL concentrations were dissolved dimethyl sulfoxide treated to human peripheral blood lymphocytes for two different treatment periods (24 48 h). In chromosome aberration (CA) micronucleus (MN) tests, did not show genotoxic effect. But it induced sister chromatid exchange (SCE) at the highest concentration (200 μg/mL) 24-h period all (except...
This study was performed to determine the cytogenetic effects of short-term thermal stress in human cultured lymphocytes. Experimental heat shock (39 °C) alone or with addition mitomycin C (MMC) synergistic antagonistic on genotoxicity induced by MMC. In this study, during culture periods 72 h, peripheral blood lymphocytes were exposed for specified durations (30, 60, 120, and 240 min) 24 48 h before harvest. According our results, selected temperatures did not show genotoxic mutagenic...
Şakok armudu (Pyrus elaeagnifila Pallas) doğal olarak yetişen yabani bir armut türüdür. Hasattan sonra olgunlaşır ve yenebilir. Bu çalışma Elazığ’da şakok armudunun toplam fenolik madde, flavanoid askorbik asit, glutatyon (GSH) süperoksid dismutaz (SOD) içeriklerinin; antioksidan aktivite, antimikrobiyal aktivite mutajenik aktivitesinin belirlenmesini kapsamaktadır. Elde edilen verilere göre örneklerin madde içeriği 174.2 mg GAE (gallik asit eşdeğeri)/100g ekstrakt, 44.9 RE (rutin 14.5 AE...
Ribes L. cinsine ait bitkiler çoğu zaman doğal olarak yetişen, son zamanlarda da kültürü yapılan çalı formundaki bitkilerdir. Bu cinse olan bektaşi üzümü ve frenk üzümünün sağlık açısından çeşitli faydalara sahip olduğu bilinmekte olup, bu faydalarından dolayı yıllarda insanoğlunun dikkatini cezbetmiş durumdadır. çalışmada Beşikdüzü/Trabzon’dan toplanmış (Ribes uva-crispa L.) dağ alpinum toplam askorbik asit, fenolik flavonoid içerikleri ile antioksidan, antibakteriyel mutajen aktivileri...
Aims: It was aimed to investigate two sour cherry genotypes such as SC genotype which is a small-fruited wild and LC large-fruited cultivated in this study.
 
 Material methods: Total phenolic, flavonoid, ascorbic acid contents, antioxidant activity (DPPH, ABTS, FRAP), sorbic, benzoic acids sugar antibacterial activities (agar well diffusion, MIC, MBC, MTC) were studied. Additionally, Salmonella typhimurium revision tests made.
 Results: observed that the had higher values for...
Abstract In this study, the chromosomal aberrations (CAs) and sister chromatid exchanges (SCEs) were investigated in human lymphocytes treated with spiramycin antibiotic (trade name, rovamycin). Spiramycin did not induce CAs SCEs, also decrease mitotic index (MI). However, decreased replication (RI) only at 48 h treatment times. Teratogenesis Carcinog. Mutagen. 22:51–58, 2002. © 2002 Wiley‐Liss, Inc.
Objectives: In the past decade, advances in immunological therapy have increased survival of kidney recipients and their grafts.However, it has not achieved desired level improvement.This study aims to reveal mortality among recipients.Methods: Medical data patients, who had undergone transplantation (KT) between November 2010 December 2020, were retrospectively reviewed.Inclusion criteria adult recipients, died.Exclusion pediatric en bloc dual KT, with missing data, a primary...
Crataegus cinsine ait Rosaceae ailesinin geleneksel tıpta kullanılan ve en önemli yenilebilir bitkilerindendir. Bu bitkiler içerdikleri farklı biyoaktif doğal bileşenler sayesinde çeşitli fizyolojik farmakolojik aktivitelere sahiptirler. çalışmada Elazığ ilinde yetişen dört türünün (C. monogyna JACQ., C. tanacetifolia (LAM.) PERS, orientalis PALLAS EX BIEB., sinaica BOISS.) toplam fenolik madde, flavanoid askorbik asit içerikleri ile antioksidan, antibakteriyel mutajenik aktivitelerinin...
In the past decade, advances in immunological therapy have increased survival of kidney recipients and their grafts. However, it has not achieved desired level improvement. This study aims to reveal mortality among recipients.Medical data patients, who had undergone transplantation (KT) between November 2010 December 2020, were retrospectively reviewed. Inclusion criteria adult recipients, died. Exclusion pediatric en bloc dual KT, with missing data, a primary non-functioning graft. The...