A5051594644- Animal Virus Infections Studies
- Coccidia and coccidiosis research
- Metabolomics and Mass Spectrometry Studies
- Aortic Disease and Treatment Approaches
- Rabies epidemiology and control
- Cardiovascular Health and Disease Prevention
- Plant Virus Research Studies
- Neonatal and fetal brain pathology
- Mass Spectrometry Techniques and Applications
- Cardiac Imaging and Diagnostics
- Soil Management and Crop Yield
- Advanced Neuroimaging Techniques and Applications
- RNA Interference and Gene Delivery
- Probiotics and Fermented Foods
- Soil Mechanics and Vehicle Dynamics
- Aortic aneurysm repair treatments
- Electrochemical sensors and biosensors
- Phytoestrogen effects and research
- Parasitic Infections and Diagnostics
- Microbial infections and disease research
- Virus-based gene therapy research
- NF-κB Signaling Pathways
- Pharmaceutical Practices and Patient Outcomes
- Analytical Chemistry and Chromatography
- Cardiovascular Disease and Adiposity
Guizhou University
2019-2025
First Affiliated Hospital of Xi'an Jiaotong University
2022-2025
Xi'an Jiaotong University
2022-2025
Renji Hospital
2025
Beijing Institute of Technology
2021-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2022-2023
Guangxi University
2010-2023
Beijing Anding Hospital
2023
Capital Medical University
2022-2023
Université Bourgogne Franche-Comté
2022
Significant advances have been achieved for the construction of chiral skeletons containing 1,2,3-triazoles via transition-metal-catalyzed asymmetric azide–alkyne cycloaddition; however, most them limited to terminal alkynes in synthesis central chirality desymmetrization and dynamic/dynamic kinetic resolution. Enantioselective azide-internal-alkyne cycloaddition is extremely limited. Moreover, a challenging five-membered (hetero)biaryl axially molecule still underexplored. Herein, we first...
Rosmarinic acid (RA) has numerous pharmacologic effects, including anti-oxidant, anti-inflammatory, and analgesic effects. This study aimed to evaluate the preventive activity of RA in a murine model asthma investigate its possible molecular mechanisms. Female BALB/c mice sensitized challenged with ovalbumin (Ova) were pretreated (5, 10 or 20 mg/kg) at 1 h before Ova challenge. The results demonstrated that markedly inhibited increases inflammatory cells Th2 cytokines bronchoalveolar lavage...
Isoflavone components extracted from red clover have anti-inflammatory, antioxidant and immune boosting effects. We hypothesize that isoflavones (RCIs) achieve health-promoting effects via altering the gut microbiota. A total of 48 mice (20 ± 2 g) were randomly divided into a control group, low-dose group (0.05% RCIs in feed), middle-dose (0.1% high-dose (0.2% feed) with 12 per group. The feeding period was 20 d. results showed can increase daily gain decrease ratio feed to mice. organ...
Abstract Background This study aims to investigate the influence of sex on age-related changes in aortic morphology using computed tomography (CT) imaging. Method Patients who underwent contrast-enhanced chest and abdominal CT between July 2021 April 2022 were enrolled stratified into six groups. Sex-specific comparisons body surface area (BSA)-adjusted diameters tortuosity performed across different To validate consistency differences arterial changes, particularly regarding stiffness,...
Abstract Objectives To investigate the impacts of a deep learning-based iterative reconstruction algorithm on image quality and measuring accuracy bone mineral density (BMD) in low dose chest CT. Methods Phantom patient studies were separately conducted this study. The same protocol was used for phantoms patients. All images reconstructed with filter back projection, hybrid (KARL, level 3,5,7), (AIIR, low, medium high-strength). noise power spectrum (NPS) task-based transfer function (TTF)...
Abstract Oxidative stress plays an important role in the pathogenesis of virus infection and antioxidants are becoming promising candidates as therapeutic agents. This study is designed to investigate effect total flavonoids Spatholobus suberectus Dunn (TFSD) on oxidative mice induced by porcine circovirus type 2 (PCV2) infection. The PCV2 leads significant decrease thymus spleen indices, elevation xanthine oxidase (XOD) myeloperoxidase (MPO) activities, reduction GSH level GSSG ratio...
In many practical tasks, there are usually two kinds of common information: cheap unlabeled data and domain knowledge in the form symbols. There some attempts using one single information source, such as semi-supervised learning abductive learning. However, is little work to use these sources at same time, because it very difficult combine symbolic logical representation numerical model optimization effectively. The becomes even more challenging when insufficient. this paper, we present an...
Effective purification and enrichment of polypeptide antibiotics in animal tissues is always a challenge, due to the co-extraction other endogenous peptides which usually interfere their final determination. In this study, molecularly imprinted column was prepared by packing polymyxin E-imprinted particles into 100 mm × 4.6 i.d. HPLC column. The as-prepared columns were able tolerate 100% aqueous phase exhibited good stability high efficiency. Polypeptides with similar molecular size or...
This study was carried out to investigate the effect of total flavonoids Spatholobus suberectus Dunn (TFSD) on PCV2 induced oxidative stress in RAW264.7 cells.Oxidative model established cells by infecting with PCV2. Virus infected were then treated various concentrations (25 mg/ml, 50 mg/ml and 100 mg/ml) TFSD. The levels related molecules (NO, ROS, GSH GSSG) activities associated enzymes (SOD, MPO XOD analyzed using ultraviolet spectrophotometry, fluorescence method commercialized...
Recent studies have demonstrated that rosmarinic acid is a valuable natural product for treatment of alcoholic liver disease. However, the mechanisms whereby improves disease remain unclear. Here we performed experiments using non-transformed mouse hepatocyte cell line (AML12). Oil-red O staining reduced ethanol-induced lipid accumulation. It was shown prevented elevation malondialdehyde level. We also found inhibited mRNA expression tumor necrosis factor-α and interleukin 6. Metabolomics...
Low muscle mass is related to cardiovascular risk factors. This study aimed investigate whether relative low the diameter and tortuosity of aorta. We performed a cross-sectional 208 adults without known disease who underwent Computed Tomography (CT) enhanced scan between 2020 2021. Skeletal index (SMI) was estimated. The morphology aorta measured by using CT. assessed relationship SMI Spearman correlation analysis univariate multivariate-adjusted regression models. Of all -individuals, 124...
The rapid and accurate authentication of traditional Chinese medicines (TCMs) has always been a key scientific technical problem in the field pharmaceutical analysis. Herein, novel heating online extraction electrospray ionization mass spectrometry (H-oEESI-MS) was developed for direct analysis extremely complex substances without requirement any sample pretreatment or pre-separation steps. overall molecular profile fragment structure features various herbal could be completely captured...
Deep vertical rotary tillage (DVRT) is a new method which combines the advantages of deep and tillage. However, limited research has been conducted on critical component tiller, namely spiral cutter. In clay loam, there are lot large clods in topsoil layer after tillage, cutting resistance vibration cutter substantial. To reveal reasons behind this, simulation model cutter–soil system was developed using Smoothed Particle Hydrodynamics (SPH). Using this model, working process force were...
Introduction The pharmacokinetic profile and residue depletion of eugenol in carp ( Cyprinus carpio ) tissues plasma were performed by a convenient reliable high-performance liquid chromatography (HPLC) method. Methods was extracted with mixed solution acetonitrile methanol. N-hexane used to remove lipid impurities. method successfully applied the elimination after administered medicated bath. Results average recoveries fortified four concentration levels 69.0–106.6% 80.0–86.7%,...
Seaweeds are excellent source of bioactive compounds and seaweed-derived polysaccharides have demonstrated an array biological effects. Here, we investigated the effect polysaccharide Sargassum weizhouense (PSW) on inflammatory response in porcine circovirus type 2 (PCV2) infected mice underlying mechanism was studied according to histone acetylation. After PCV2 infection, levels TNF-α, IL-1β, IL-6, IL-8, IL-10, MCP-1, COX-1, COX-2 HAT both serum spleen were significantly increased (P...