A5064686214- Liver Disease Diagnosis and Treatment
- Diabetes Management and Research
- Lipid metabolism and disorders
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diabetes and associated disorders
- Diabetes Treatment and Management
- Pancreatic function and diabetes
- Thyroid Disorders and Treatments
- Metabolism, Diabetes, and Cancer
- Bariatric Surgery and Outcomes
- Genetic Associations and Epidemiology
- Diet and metabolism studies
- Chronic Kidney Disease and Diabetes
- Growth Hormone and Insulin-like Growth Factors
- Gestational Diabetes Research and Management
- Nutrition and Health in Aging
- ECG Monitoring and Analysis
- Pain Mechanisms and Treatments
- Cardiovascular Disease and Adiposity
- Cancer, Hypoxia, and Metabolism
- Gout, Hyperuricemia, Uric Acid
- Alcohol Consumption and Health Effects
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Ginseng Biological Effects and Applications
- Nutritional Studies and Diet
Shanghai Jiao Tong University
2025
Jiangsu University
2016-2025
First People's Hospital of Kunshan
2016-2025
Hubei University
2025
Third Affiliated Hospital of Southern Medical University
2025
Nanjing Medical University
2023-2024
Nanjing Institute of Technology
2024
Liaoning Shihua University
2021
Nanjing University of Chinese Medicine
2018
University of Maryland, Baltimore
2008-2015
Purpose Obesity, particularly abdominal obesity, is seen as a risk factor for diabetic complications. The weight-adjusted-waist index (WWI) recently developed measuring adiposity. Our goal was to uncover the potential correlation between WWI and kidney disease (DKD) risk. Methods This cross-sectional study included adults with type 2 diabetes mellitus (T2DM) who participated in NHANES database (2007-2018). calculated waist circumference (WC, cm) divided by square root of weight (kg). DKD...
Abstract The elevation of serum alanine aminotransferase (ALT) is regarded as an indicator liver damage based on the presumption that ALT protein specifically and abundantly expressed in liver. However, also observed non–liver injury conditions (for example, muscle injury) apparently healthy people. Conversely, activity normal many patients with confirmed diseases cirrhosis hepatitis C infection). To improve diagnostic value assay to understand molecular basis for changes various...
Triglyceride-glucose (TyG) index is a convenient indicator of insulin resistance. It has been shown to be associated with macrovascular and microvascular complications in nonhospitalized diabetic patients. However, whether TyG risk factor diabetes vascular hospitalized type 2 patients unclear. We sought explore the association between large Chinese cohort patients.A total 4,721 (T2D) who were Department Endocrinology, Kunshan Hospital Affiliated Jiangsu University enrolled January 2015...
Triglyceride-glucose (TyG) index is a simple and reliable indicator of metabolic dysfunction. We aimed to investigate possible relationship between TyG albuminuria in the United States adult population.This cross-sectional study was conducted among adults with complete urinary albumin/urinary creatinine (UACR) from 2011-2018 National Health Nutrition Examination Survey (NHANES). The independent (UACR>30mg/g) evaluated. compared insulin resistance represented by homeostatic model assessment...
Abstract Background Alanine transaminase (ALT) plays an important role in gluconeogenesis by converting alanine into pyruvate for glucose production. Early studies have shown that ALT activities are upregulated gluconeogenic conditions and may be implicated the development of diabetes. consists two isoforms, ALT1 ALT2, with distinctive subcellular tissue distributions. Whether how they regulated largely unknown. Methods By using Western blotting analysis, we measured hepatic isoforms at...
Abstract Remnant cholesterol (RC) is closely related to metabolic diseases. Our study aims explore the relationship between RC and hyperuricemia. This cross-sectional included 14 568 adults aged 20 years or older from National Health Nutrition Examination Survey (NHANES) conducted 2007 2018 in United States. calculated by subtracting high-density lipoprotein (HDL-c) low-density (LDL-c) total (TC). Hyperuricemia defined serum uric acid (SUA) levels≥7 mg/dl men and≥6 women. The independent...
Tert-butylhydroquinone (tBHQ), an Nrf2 activator, has demonstrated neuroprotection against brain trauma and ischemic stroke in vivo. However, little work been done with respect to its effect on early injury (EBI) after subarachnoid hemorrhage (SAH). At the same time, as oral medication, it may have extensive clinical applications for treatment of SAH-induced cognitive dysfunction. This study was undertaken evaluate influence tBHQ EBI, secondary deficits learning memory, Keap1/Nrf2/ARE...
Predicting hypoglycemia while maintaining a low false alarm rate is challenge for the wide adoption of continuous glucose monitoring (CGM) devices in diabetes management. One small study suggested that deep learning model based on long short-term memory (LSTM) network had better performance prediction than traditional machine algorithms European patients with type 1 diabetes. However, given many well-recognized models perform poorly outside training setting, it remains unclear whether LSTM...
Copper plays crucial roles in fundamental life processes, including proliferation, metabolism, and survival. deficiency is associated with multiple diseases, such as nonalcoholic fatty liver disease (NAFLD) Wilson's disease. Therapeutic programs targeting copper supply are prospectively employed for intervention. Herein, we developed biofriendly ionophores (HQFs) by constructing pseudonatural flavonols, which possess flavonoid bioactivity enhanced transport properties. In cell models mice,...
Abstract Aims To evaluate the clinical profile of patients with diabetic ketoacidosis in tertiary hospitals China. Methods A retrospective study hospitalized between 2010 and 2012 was carried out 15 around Clinical laboratory data were collected. Patients classified based on diagnosis treatment history. Groups compared for differences vital statistics biochemical profiles at presentation. Results The comprised 643 ketoacidosis: 308 (47.9%) Type 1 diabetes, 294 (45.7%) 2 diabetes 41 (6.4%)...
The thyroid gland exhibits a subtle interconnection with the lungs. We further investigated correlation between hormone sensitivity and lung function in euthyroid individuals.
Objective: Type 2 diabetes mellitus (T2DM) is a metabolic disease characterized by insulin resistance and progressively impaired secretion resulting in dynamic fluctuations glucose levels.High blood urea nitrogen (BUN) levels have been linked to decreased sensitivity, suppressed synthesis increased risk of incident humans as well use patients with T2DM.This study characterize the association between BUN short-term long-term glycemic variability(GV) elderly T2DM who were hospitalized....
Evidence suggests that incretin-based dual agonist pharmacotherapy is helpful in persons with obesity. Mazdutide, a glucagon-like peptide-1 and glucagon receptor agonist, may have efficacy overweight or In phase 3, double-blind, placebo-controlled trial China, we randomly assigned, 1:1:1 ratio, adults 18 to 75 years of age who had body-mass index (BMI; the weight kilograms divided by square height meters) at least 28 BMI 24 less than plus one weight-related coexisting condition receive 4 mg...
The aging population is increasingly susceptible to cardiovascular disease (CVD). Visit-to-visit variability in glucose and lipid levels both contributed CVD risk independent of their mean values. However, whether the triglyceride-glucose (TyG) index a factor for remains unknown. Research Design Methods. In this retrospective study electronic health records, 27,520 participants aged over 60 years were enrolled. visit-to-visit TyG was calculated from annual examination data defined as average...