A5100644254- Pain Mechanisms and Treatments
- Pituitary Gland Disorders and Treatments
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Liver Disease Diagnosis and Treatment
- Growth Hormone and Insulin-like Growth Factors
- Adipokines, Inflammation, and Metabolic Diseases
- Botulinum Toxin and Related Neurological Disorders
- Cardiovascular Health and Disease Prevention
- Diabetes and associated disorders
- Diabetic Foot Ulcer Assessment and Management
- Chronic Kidney Disease and Diabetes
- Adrenal and Paraganglionic Tumors
- Cardiovascular Function and Risk Factors
- Pharmacological Effects of Natural Compounds
- Blood Pressure and Hypertension Studies
- Diabetes Management and Research
- Diabetes Treatment and Management
- Advancements in Battery Materials
- Helicobacter pylori-related gastroenterology studies
- Advanced Battery Materials and Technologies
- Smart Grid and Power Systems
- Digestive system and related health
- Ophthalmology and Eye Disorders
- Pancreatic function and diabetes
- Lipid metabolism and disorders
Wenzhou Medical University
2011-2025
Fudan University
2016-2025
Zhejiang DongFang Vocational and Technical College
2025
Affiliated Hospital of Youjiang Medical University for Nationalities
2025
Baise University
2025
Dongyang People's Hospital
2022-2025
Huadong Hospital
2025
Huashan Hospital
2015-2024
Chinese PLA General Hospital
2020-2024
Jimei University
2022-2024
Abstract Objective We aimed to investigate whether elevated serum uric acid concentrations are associated with higher risk of metabolic syndrome (MetS) and carotid atherosclerosis in patients type 2 diabetes. Methods conducted a population-based cross-sectional survey Shanghai, total 395 men 631 women age 41 92 years. The artery intima-media thickness (IMT) atherosclerotic plaques (PLQ) were measured by B-mode ultrasound. MetS was defined according the updated National Cholesterol Education...
Abstract Background Insulin resistance is associated with chronic complications of diabetes, including diabetic peripheral neuropathy (DPN). Estimated glucose disposal rate (eGDR), calculated by the common available clinical factors, was proved to be an excellent tool measure insulin in large patient population. Few studies have explored association between eGDR and DPN longitudinally. Therefore, we performed current study analyze whether could predict risk DPN. Methods In this prospective...
This study determined the prevalence and factors associated with peripheral neuropathy (PN) in subjects diabetes mellitus, impaired glucose regulation (IGR), normal tolerance (NGT) a community-based Chinese population.
Serum lipids and the ratios are known to be associated with cardiovascular diseases (CVD). However, associations of serum related arterial stiffness unclear. We sought compare strength these assessing by brachial-ankle pulse wave velocity (baPWV) in middle-aged elderly Chinese subjects. A total number 1133 aged from 50 90 years old were recruited Shanghai downtown district. The lipids, baPWV major risk factors participants measured. Participants high exhibited higher levels non-HDL-c,...
Lipocalin-2 is a novel adipokine with connection to insulin resistance. In this study, we aimed investigate the association of serum lipocalin-2 glucose metabolism and other metabolic phenotype in large-scale Chinese population. We evaluated cross-sectional sample 2519 aged from 50 82 year Shanghai downtown district by ELISA. Glucose, insulin, lipid profile, inflammatory markers, adipokines were also measured. Serum was significantly higher subjects isolated impaired fasting glucose,...
Inflammation has been implicated in the pathogenesis of diabetic peripheral neuropathy (DPN) as suggested various cross-sectional studies. However, more convincing prospective studies diabetes patients are scarce. Therefore, we aimed to evaluate whether proinflammatory cytokines could predict incidence DPN through a study with five-year follow-up.We followed up 315 who did not have DPN, recruited from five community health centers Shanghai 2014, for an average 5.06 years. Based on integrity...
Remote sensing super-resolution (RSSR) aims to improve remote (RS) image resolution while providing finer spatial details, which is of great significance for high-quality RS interpretation. The traditional RSSR based on the optimization method, pays insufficient attention small targets and lacks ability model understanding detail supplement. To alleviate above problems, we propose generative Diffusion Model with Detail Complement (DMDC) super-resolution. Firstly, unlike models understanding,...
Diabet. Med. 30, 309–317 (2013) Abstract Aim To assess the relationship between serum total osteocalcin and measurements of adiposity, glucose tolerance, lipid profile, adipokine chronic low‐grade inflammation in middle‐aged elderly Chinese subjects. Methods We performed a cross‐sectional community‐based study central Shanghai. Serum was measured by radioimmunoassay 783 men 946 post‐menopausal women. Their associations with profile were examined. Results levels revealed sexual dimorphism,...
To determine the association of insulin resistance, metabolic syndrome (MetS) with peripheral neuropathy (PN).This cross-sectional study consisted 2035 subjects in Shanghai who were classified as MetS and without MetS. The new International Diabetes Federation (IDF) criterion was used to define HOMA-IR applied evaluate resistance. All underwent complete foot examination. PN assessed according symptom disability scores. Binary logistic regression performed analyze contributions features...
Chronic inflammation plays a pivotal role in insulin resistance and type 2 diabetes, yet the mechanisms are not completely understood. Here, we demonstrated that serum LPS levels were significantly higher newly diagnosed diabetic patients than normal control. miR-145 level peripheral blood mononuclear cells decreased diabetics. repressed transcription of miR-143/145 cluster levels. Attenuation activity by anti-miR-145 triggered liver increased chemokines C57BL/6 J mice. Conversely,...
Objective The present study aims to investigate the effect of Helicobacter pylori (Hp) infection on gastric mucosal microbiota in patients with chronic gastritis. Methods Here recruited a population 193 both gastritis and positive rapid urease, including 124 atrophic (CAG) 69 non-atrophic (nCAG). Immunoblotting was used detect four serum Hp antibodies (UreA, UreB, VacA CagA) determine types virulent Hp-I avirulent Hp-II infections. Gastric profiled by 16S rRNA gene V3-V4 region, R software...
Type 2 diabetes mellitus (T2DM) is more prevalent in aging populations. Older adults with have higher rates of macro and micro vascular complications. Our study assessed whether age an independent factor for both large small nerve dysfunctions Chinese patients T2DM. This cross-sectional involved a total 950 type (mean age: 60.01±12.30 years). Diabetic peripheral neuropathy (DPN) was according to clinical symptoms physical examinations by using symptom score (NSS), the disability (NDS),...