A5053448144- Advanced Radiotherapy Techniques
- Prostate Cancer Diagnosis and Treatment
- Glioma Diagnosis and Treatment
- Meningioma and schwannoma management
- Head and Neck Cancer Studies
- Brain Metastases and Treatment
- HIV Research and Treatment
- Prostate Cancer Treatment and Research
- Head and Neck Surgical Oncology
- Radiation Therapy and Dosimetry
- HIV/AIDS Research and Interventions
- Ear and Head Tumors
- Effects of Radiation Exposure
- Endometrial and Cervical Cancer Treatments
- Radiomics and Machine Learning in Medical Imaging
- Ocular Oncology and Treatments
- Pneumocystis jirovecii pneumonia detection and treatment
- Hepatitis C virus research
- Vaccine Coverage and Hesitancy
- Immune Response and Inflammation
- Cytokine Signaling Pathways and Interactions
- Cancer Risks and Factors
- vaccines and immunoinformatics approaches
- Hearing, Cochlea, Tinnitus, Genetics
- Fungal Infections and Studies
National Heart Lung and Blood Institute
2024-2025
Columbia University
2025
Eunice Kennedy Shriver National Institute of Child Health and Human Development
2024
City College of New York
2017
National Institute of Allergy and Infectious Diseases
2004-2012
National Institutes of Health
2011-2012
Armed Forces Research Institute of Medical Science
1998-2009
Institute of Medical Sciences
2009
Baylor College of Medicine
1998-2008
Methodist Hospital
1993-2008
The development of a safe and effective vaccine against the human immunodeficiency virus type 1 (HIV-1) is critical to pandemic control.In community-based, randomized, multicenter, double-blind, placebo-controlled efficacy trial, we evaluated four priming injections recombinant canarypox vector (ALVAC-HIV [vCP1521]) plus two booster glycoprotein 120 subunit (AIDSVAX B/E). placebo were administered 16,402 healthy men women between ages 18 30 years in Rayong Chon Buri provinces Thailand....
Objective: To compare pyrimethamine plus clindamycin (PC) to sulfadiazine (PS) as a treatment for toxoplasmic encephalitis (TE) in patients with the acquired immunodeficiency syndrome (AIDS). Design: Randomized, unblinded phase II, multi-center trial provision crossover failure or intolerance of assigned regimen. Setting: University hospitals. Patients: Eighty-four presumptive TE were entered. Thirteen excluded when they found have another diagnosis, and 12 because did not meet entry...
In patients with the acquired immunodeficiency syndrome (AIDS), rate of relapse after primary treatment for cryptococcal meningitis remains high. We conducted a controlled, doubleblind trial to evaluate efficacy maintenance therapy fluconazole. At entry into study, all participants had sterile cultures cerebrospinal fluid, blood, and urine following standardized course culture-proved meningitis. The were randomly assigned take either fluconazole or placebo as therapy. dose was 100 mg daily...
Background —Intracoronary γ- and β-radiation have reduced restenosis in animal models. In the clinical setting, effectiveness of β-emitters has not been studied a broad spectrum patients, particularly those receiving stents. Methods Results —A prospective, randomized, sham-controlled study intracoronary radiotherapy with β-emitting 32 P source wire, using centering catheter automated delivery unit, was conducted. A total 105 patients de novo (70%) or restenotic (30%) lesions who were treated...
Objective: To determine the efficacy of combination drug therapy for disseminated Mycobacterium avium complex infection in patients with acquired immunodeficiency syndrome (AIDS). Design: Prospective, nonrandomized, before-after comparison. Setting: Outpatient clinics at three university medical centers. Patients: Seventeen least two consecutive blood cultures positive M. who had not been previously treated antituberculous medications. Fifteen seventeen completed 4 weeks treatment....
▪ Objective: To determine the quantitative microbiologic response and clinical of patients with Mycobacterium avium complex bacteremia AIDS to an oral antimycobacterial regimen. Design: A phase II, multicenter trial. Setting: Four university-affiliated medical centers. Patients: Forty-one HIV infection who had at least two consecutive blood cultures positive for M. not received previous therapy were enrolled in study. Thirty-one valuable regard efficacy Interventions: Patients a combination...
PURPOSE The purpose of this study was to investigate the role a rectal balloon for prostate immobilization and toxicity reduction in patients receiving dose-escalated intensity-modulated radiotherapy cancer. PATIENTS AND METHODS Patients with localized cancer who were undergoing treated prone position, immobilized customized Vac-Lok bag (MED-TEC, Orange City, IA). A 100 cc air used immobilize prostate. displacements measured using computed tomography (CT)-CT fusion on 10 received radioactive...
Background A prime-boost vaccination regimen with ALVAC-HIV (vCP1521) administered intramuscularly at 0, 4, 12, and 24 weeks gp120 AIDSVAX B/E 12 demonstrated modest efficacy of 31.2% for prevention HIV acquisition in HIV-uninfected adults participating a community-based trial Thailand. Methodology/Principal Findings Reactogenicity was recorded 3 days following vaccination. Adverse events were monitored every 6 months 3.5 years, during which pregnancy outcomes recorded. Of the 16,402...
Trigeminal neuralgia is a paroxysmal pain syndrome commonly associated with multiple sclerosis. While gamma knife radiosurgery has been shown to be an effective treatment for most cases of trigeminal neuralgia, it considered less efficacious in patients sclerosis and viable as option.Seven multiple-sclerosis-associated were identified from 50 consecutive treated at the Memorial-Hermann Gamma Knife Radiosurgery Center. A Leksell was used deliver 80 or 90 Gy single 4-mm isocenter targeting...