A5034251567- Characterization and Applications of Magnetic Nanoparticles
- Geomagnetism and Paleomagnetism Studies
- Magnetic properties of thin films
- Nanoparticle-Based Drug Delivery
- Microfluidic and Bio-sensing Technologies
- Advancements in Battery Materials
- Iron oxide chemistry and applications
- Magnetic Properties and Synthesis of Ferrites
- Material Dynamics and Properties
- Magnetic and Electromagnetic Effects
- Electrical and Bioimpedance Tomography
- Electromagnetic wave absorption materials
- Electrostatics and Colloid Interactions
- Surfactants and Colloidal Systems
- Magnetic Properties of Alloys
University of Florida
2017-2022
Cornell University
2017
Decades of research focused on size and shape control iron oxide nanoparticles have led to methods synthesis that afford excellent over physical but comparatively poor magnetic properties. Popular based thermal decomposition organometallic precursors in the absence oxygen yielded particles with mixed phases, crystal defects, poorer than expected properties, including existence a thick "magnetically dead layer" experimentally evidenced by diameter significantly smaller diameter. Here, we show...
Background: Magnetic nanoparticles (MNPs) generate heat when exposed to an alternating magnetic field. Consequently, MNPs are used for fluid hyperthermia (MFH) cancer treatment, and have been shown increase the efficacy of chemotherapy and/or radiation treatment in clinical trials. A downfall current MFH is inability deliver sufficient tumor due to: insufficient amounts MNPs, unequal distribution throughout tumor, or loss surrounding environment. Objective: In this study, objective was...
Abstract Magnetic nanoparticles have many advantages in medicine such as their use non‐invasive imaging a Particle Imaging (MPI) tracer or Resonance contrast agent, the ability to be externally shifted actuated and excited generate heat release drugs for therapy. Existing gentle sigmoidal magnetization response that limits resolution sensitivity. Here it is shown superferromagnetic iron oxide nanoparticle chains (SFMIOs) achieve an ideal step‐like improve both image & SNR by more than...
Superparamagnetic iron oxide nanoparticle (SPION) tracers possessing long blood circulation time and tailored for magnetic particle imaging (MPI) performance are crucial the development of this emerging molecular modality.Here, single-core SPION MPI coated with covalently bonded polyethyelene glycol (PEG) brushes were obtained using a semi-batch thermal decomposition synthesis controlled addition oxygen, followed by an optimized PEG-silane ligand exchange procedure.The physical properties,...
Polymer-coated nanoparticles in synovial fluid and hyaluronic acid solutions diffuse faster than expected based on bulk viscosity.
This paper presents the design, construction, and testing of a magnetic particle relaxometer (MPR) to assess nanoparticle response dynamic fields while subjected bias field. The designed MPR can characterize particles for use as tracers in imaging (MPI), with variation an applied field emulating scan MPI free point. system applies high-frequency time-varying excitation (up 45 mT at 30 kHz), slowly ramping (±100 1 s). time-resolved sample is measured using inductive sensing coil system, made...
Superferromagnetic iron oxide (SFMIOs) is a new paradigm for Magnetic Particle Imaging (MPI) as it approaches the ideal imaging agent characteristics of steep, step-like magnetization curve. Other than expected 10-fold SNR and spatial resolution improvements from square-like hysteresis curve, we demonstrate other unique qualities SFMIOs that enable robust "chemical-shift-like" color multiplexing to potentially range magnetic "dyes" work at-depth imaging. We also extremely high sensitivity...
Magnetic nanocomposites with 0-3 connectivity, whereby a 0D magnetic nanoparticle phase is embedded into 3D metal matrix phase, have gained increased interest for use in applications ranging from integrated power inductor cores to exchange-spring magnets. The electro-infiltration process, which electroplated through film an inexpensive approach compatible semiconductor fabrication methods the formation of these nanocomposites. Past demonstrations electro-infiltrated relied on scanning...