A5091589551- Algal biology and biofuel production
- Advanced Proteomics Techniques and Applications
- Monoclonal and Polyclonal Antibodies Research
- Biofuel production and bioconversion
- Seaweed-derived Bioactive Compounds
- Protein purification and stability
- Biocrusts and Microbial Ecology
- Genomics and Phylogenetic Studies
- Microbial Community Ecology and Physiology
- Minerals Flotation and Separation Techniques
- Constructed Wetlands for Wastewater Treatment
- Moringa oleifera research and applications
- Photosynthetic Processes and Mechanisms
- Protist diversity and phylogeny
- Mass Spectrometry Techniques and Applications
- Solar-Powered Water Purification Methods
- Antioxidant Activity and Oxidative Stress
- Viral Infectious Diseases and Gene Expression in Insects
- Membrane Separation Technologies
- Plant biochemistry and biosynthesis
- Microbial Metabolic Engineering and Bioproduction
- Protein Hydrolysis and Bioactive Peptides
- Aquatic Ecosystems and Phytoplankton Dynamics
University of Sheffield
2015-2020
Plymouth Marine Laboratory
2017-2019
Rothamsted Research
2017-2019
Plant triterpenoids constitute a diverse class of organic compounds that play major role in development, plant defence and environmental interaction. Several triterpenes have demonstrated potential as pharmaceuticals. One example is betulin, which has shown promise pharmaceutical precursor for the treatment certain cancers HIV. Major challenges triterpenoid commercialization include their low production levels cost-effective purification from complex mixtures present natural hosts....
The use of microorganisms as cell factories frequently requires extensive molecular manipulation. Therefore, the identification genomic neutral sites for stable integration ectopic DNA is required to ensure a successful outcome. Here we describe genome mapping and validation five in chromosome Synechocystis sp. PCC 6803, foreseeing this cyanobacterium photoautotrophic chassis. To evaluate neutrality these loci, insertion/deletion mutants were produced, assess their functionality, synthetic...
Electro-coagulation floatation (ECF) is a foam-floatation dewatering method that has been shown to be highly effective, rapid, and scalable separation methodology. In this manuscript, an in-depth analysis of the gas flocculant levels observed during process provided, with microbubbles in 5–80 μm size range at concentration 102–103 bubbles mL−1. Electrolysis microalgae culture was then observed, demonstrating both effective using aluminium electrodes (nine microalgal species tested, 1–40...
CyanoFactory, Design, construction and demonstration of solar biofuel production using novel (photo)synthetic cell factories, was an R&D project developed in response to the European Commission FP7-ENERGY-2012-1 call "Future Emerging Technologies" need for significant advances both new science technologies convert energy into a fuel. CyanoFactory example "purpose driven" research development with identified scientific goals creation technologies. The present overview highlights outcomes...
Abstract There are few studies defining CHO host cell proteins (HCPs) and the flux of these throughout a downstream purification process. Here we have applied quantitative iTRAQ proteomics to follow HCP profile an antibody (mAb) producing CHO‐S line standard procedure consisting Protein A, cation anion exchange We used both 6 sample experiment analyze technical replicates three samples, which were culture harvest (HCCF), A flow through eluate 8 format four types; HCCF compared subsequent...
Seaweeds contain many varied and commercially valuable components, from individual pigments metabolites through to whole biomass, yet they remain an under cultivated underutilised commodity. Currently, commercial exploitation of seaweeds is predominantly limited biomass consumption or single product extracts for the food industry. The development a seaweed biorefinery, based around multiple products services, could provide important opportunity exploit new currently underexplored markets....