A5039481066- Bacterial Identification and Susceptibility Testing
- Mosquito-borne diseases and control
- Malaria Research and Control
- Antibiotic Resistance in Bacteria
- Viral Infections and Vectors
- Clinical Laboratory Practices and Quality Control
- Mycobacterium research and diagnosis
- Streptococcal Infections and Treatments
- Genomics and Phylogenetic Studies
- Infective Endocarditis Diagnosis and Management
- Antibiotics Pharmacokinetics and Efficacy
- Insect symbiosis and bacterial influences
- Vibrio bacteria research studies
- Respiratory viral infections research
- Influenza Virus Research Studies
- Actinomycetales infections and treatment
- Infections and bacterial resistance
- Clostridium difficile and Clostridium perfringens research
- Traditional Chinese Medicine Studies
- Hemostasis and retained surgical items
- Corneal Surgery and Treatments
- Bacillus and Francisella bacterial research
- Surgical site infection prevention
- Antimicrobial Resistance in Staphylococcus
- Infectious Diseases and Mycology
Augusta University
2017-2020
Washington University in St. Louis
2015-2020
Augusta University Health
2018-2019
University of West Florida
2017
The University of Texas Medical Branch at Galveston
2011-2013
Infections with Corynebacterium striatum have been described in the literature over last 2 decades, majority being bacteremia, central line infections, and occasionally, endocarditis. In recent years, frequency of C. infections appears to be increasing; a factor likely contributing this is increased ease accuracy identification spp., including striatum, from clinical cultures. The objective study was retrospectively characterize isolates recovered specimens submitted as part routine patient...
Previous studies of North American isolates West Nile virus (WNV) during 1999-2005 suggested that the had reached genetic homeostasis in America. However, genomic sequencing WNV from Harris County, Texas, 2002-2009 suggests this is not case. Three new groups have been identified Texas since 2005. Spread southwestern US genotype (SW/WN03) Arizona/Colorado/northern Mexico region to California, Illinois, New Mexico, York, Dakota, and Gulf Coast demonstrates continued evolution WNV. Thus,...
When mycobacteria are recovered in clinical specimens, timely species-level identification is required to establish the significance of isolate and facilitate optimization antimicrobial therapy. Matrix-assisted laser desorption ionization-time flight mass spectrometry (MALDI-TOF MS) has recently been reported be a reliable expedited method for mycobacteria, although various specimen preparation techniques databases analysis across studies. Here we compared two MALDI-TOF MS instrumentation...
Invasive fungal infections have a high rate of morbidity and mortality, accurate identification is necessary to guide appropriate antifungal therapy. With the increasing incidence invasive disease attributed filamentous fungi, rapid species-level these pathogens necessary. Traditional methods for fungi can be slow may lack resolution. Matrix-assisted laser desorption ionization-time flight mass spectrometry (MALDI-TOF MS) has emerged as method bacteria yeasts, but paucity data exists on...
Since the 1990s West Nile virus (WNV) has become an increasingly important public health problem and cause of outbreaks neurological disease. Genetic analyses have identified multiple lineages with many studies focusing on lineage 1 due to its emergence in New York 1999 neuroinvasive phenotype. Until recently, viruses 2 were not thought be importance few disease being associated this lineage. However, recent epidemics Europe (Greece Italy) Russia shown increasing There are very genetic...
Carbapenemase-producing gram-negative bacteria (CP-GNB) are an urgent and expanding public health threat. Rapid accurate identification of these organisms facilitates infection prevention efforts in healthcare facilities. The objective our study was to evaluate methods detect identify CP-GNB.We examined 189 carbapenem-resistant GNB(CR-GNB), including Enterobacteriaceae, Pseudomonas aeruginosa, Acinetobacter baumannii complex, using 3 different methods: 2 screen isolates GNB for carbapenemase...
We investigated the genetics and evolution of West Nile virus (WNV) since initial detection in United States 1999 on basis continual surveillance studies Houston, Texas, USA, metropolitan area (Harris County) as a surrogate model for WNV national scale. Full-length genomic sequencing 14 novel 2010-2012 isolates collected from resident birds Harris County demonstrates emergence 4 independent genetic groups distinct historical strains circulating greater Houston region 2002. Phylogenetic...
Mycobacterium spp. are a rare cause of endocarditis. Herein, we describe case mageritense prosthetic valve This organism produced an unusual brown pigment on solid media. Cultures tissue for acid-fast bacilli might be considered in some cases apparently culture-negative
Abstract Background Upper respiratory tract infections are common, and the ability to accurately rapidly diagnose causative pathogen has important implications for patient management. Methods We evaluated test-ordering practices 2 commonly utilized nucleic acid amplification tests (NAATs) detection of pathogens: Xpert Flu Assay influenza A/B (Flu assay) Biofire FilmArray panel assay (RP assay), which detects 20 different targets. Our study examined repeat testing; that is, testing within 7...
On behalf of the Microbiology Committee College American Pathologists (CAP), we respond to recent commentary by Kirby and colleagues on topic bringing in new antimicrobial susceptibility testing (1). The authors state that “there is a lack clarity regarding verification requirements for each antibiotic using platforms methods are already established clinical laboratory” argue quality control can be used place conventional studies (i.e., accuracy precision). While appreciate intent behind...
An 82-year-old man with dementia presented to his primary care physician a chief complaint of left eye swelling for 2 days. He was prescribed ciprofloxacin ophthalmic drops. A few days later, symptoms had not improved, and he the emergency department at an outside hospital ongoing pain. loss vision in eye. noted that may have fallen approximately weeks earlier but did seek medical care. Antimicrobial therapy intravenous ceftriaxone vancomycin initiated. MRI demonstrated detachment retina,...