A5031076931- HIV/AIDS drug development and treatment
- HIV/AIDS Research and Interventions
- HIV Research and Treatment
- Environmental Changes in China
- Botany and Plant Ecology Studies
- Land Use and Ecosystem Services
- Plant Ecology and Soil Science
- Plant Molecular Biology Research
- Pneumocystis jirovecii pneumonia detection and treatment
- Medicinal Plant Research
- Ecology and Vegetation Dynamics Studies
- thermodynamics and calorimetric analyses
- Rangeland Management and Livestock Ecology
- Soil Carbon and Nitrogen Dynamics
- Seedling growth and survival studies
- Respiratory viral infections research
- Pomegranate: compositions and health benefits
- Remote Sensing in Agriculture
- Influenza Virus Research Studies
- Plant Stress Responses and Tolerance
- Agriculture, Soil, Plant Science
- Moringa oleifera research and applications
- Aquaculture disease management and microbiota
- Species Distribution and Climate Change
- Environmental and Agricultural Sciences
Harvard University
2013-2024
Dalian Minzu University
2007-2024
Northeast Agricultural University
2019-2020
Research Center for Eco-Environmental Sciences
2007
Chinese Academy of Sciences
2007
Institute of Botany
2007
Background. Concomitant use of rifamycins to treat or prevent tuberculosis can result in subtherapeutic concentrations antiretroviral drugs. We studied the interaction efavirenz with daily rifapentine and isoniazid human immunodeficiency virus (HIV)–infected individuals receiving a 4-week regimen tuberculosis.
Background. Low-frequency nevirapine (NVP)–resistant variants have been associated with virologic failure (VF) of initial NVP-based combination antiretroviral therapy (cART) in women prior exposure to single-dose NVP (sdNVP). We investigated whether a similar association exists without sdNVP exposure.
Objective: Risk factors for progression from prediabetes mellitus (pre-DM) to diabetes (DM) among people with HIV (PWH) receiving modern antiretroviral therapy (ART) require better characterization. Design: AIDS Clinical Trials Group (ACTG) A5322 (HAILO) was an observational cohort study of PWH ≥40 years old. Participants initiated ART through ACTG randomized clinical trials. Methods: We used Cox proportional hazards regression models identify risk development DM HAILO participants pre-DM....
Alfalfa is an important salt-tolerant leguminous forage-plant in salinity areas worldwide, but its performance high level of salt stress cannot meet the satisfactory requirement. Especially, short-term response alfalfa to high-level still not clear. In present study, thirty-day-old Gongnong No. 1 (Medicago sativa L. cv. No.1) seedlings were exposed NaCl treatments at concentrations 0 (control), 50 (moderate level), 150 (high and 250 mM (extremely level). Twenty-four hours after treatment,...
Background. Combination antiretroviral therapy (cART) reduces genital tract human immunodeficiency virus type 1 (HIV-1) load and the risk of sexual transmission, but little is known about efficacy cART for decreasing viral (GTVL) differences in sex or HIV-1 subtype.
Background: Limited comparative, prospective data exist regarding cardiovascular risk factors in HIV-infected women starting antiretroviral therapy Africa. Methods: In 7 African countries, 741 with CD4 <200 cells/mm3 were randomized to tenofovir/emtricitabine (TDF/FTC) plus either nevirapine (NVP, n = 370) or lopinavir/ritonavir (LPV/r, 371). Lipids and blood pressure (BP) evaluated at entry, 48, 96, 144 weeks. Multivariable linear logistic regression models used evaluate mean factor changes...
The use of rifamycin antibiotics for TB prevention carries a risk detrimental drug-drug interactions with concomitantly used ART.To evaluate the interaction antiretroviral drug nevirapine in combination 4 weeks daily rifapentine and isoniazid people living HIV.Participants were individuals enrolled BRIEF-TB study receiving randomized to rifapentine/isoniazid arm study. Participants provided sparse pharmacokinetic (PK) sampling at baseline 2 trough determination. Nevirapine apparent oral...
Duration of viral shedding is a determinant infectivity and transmissibility, but few data exist about oseltamivir's ability to alter shedding.From January 2012 through October 2017, randomized, double-blinded multicenter clinical trial was conducted in adults aged 18-64 years at 42 sites Thailand, the United States, Argentina. Participants with influenza A or B without risk factors for complications were screened study. Eligible participants randomized receive oseltamivir 75 mg placebo...
Objectives The effect of rifapentine plus isoniazid on efavirenz pharmacokinetics was characterized in AIDS Clinical Trials Group protocol A5279 (NCT01404312). present analyses characterize pharmacogenetic interactions between these drugs, and with nevirapine. Methods A subset HIV-positive individuals receiving efavirenz- or nevirapine-containing antiretroviral therapy underwent pharmacokinetic evaluations at baseline, again weeks 2 4 after initiating daily isoniazid. Associations...
The response of plant growth to a geographical salinity gradient under the current scenario from inland seaside implies possible future trend development in sea-level rise driven by global warming. In present study, alfalfa (Medicago sativa L. cv. Gongnong No. 1) was planted sites along Dalian City, Northeast China. Fine root investigated at three depths 0–10 cm, 10–20 cm and 20–30 cm. Meanwhile, another control experiment conducted using potted exposed gradual levels same as gradients field...
Abstract Background Caloric value is an important indicator of grassland ecosystem function, but the response caloric to nitrogen (N) addition and mowing still unclear. We explored adaptive changes plant energy standing crop along a N gradient after six-year NH 4 NO 3 treatments in Inner Mongolian temperate meadow steppe northern China. Results found that at different organizational levels was diverse. The legumes increased linearly with rates. grasses exhibited non-linear trend, initially...
Objective: The primary objective of the study was to assess immunogenicity an HIV-1 Gag conserved element DNA vaccine (p24CE DNA) in people with HIV (PWH) receiving suppressive antiretroviral therapy (ART). Design: AIDS Clinical Trials Group A5369 a phase I/IIa, randomized, double-blind, placebo-controlled PWH ART plasma RNA less than 50 copies/ml, current CD4 + T-cell counts greater 500 cells/μl, and nadir 350 cells/μl. Methods: enrolled 45 participants randomized 2 : 1 receive p24CE at...
With the Longitudinal Range-Gorge Region (LRGR) in southwestern China as object, this research studied how land use pattern varies with complex topographic features. Based on 1:50000 digital elevation model (DEM) data and remote sensing images 1980, 2001, by using GIS map algebra method, we investigated relationship between landform (e.g. stream networks) use, especially correlation of human activities spatial arrangement networks. This paper reveals that cover changes valleys rich water...