A Zagatina
- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Ultrasound in Clinical Applications
- Ultrasound and Hyperthermia Applications
- Cardiovascular Disease and Adiposity
- Coronary Interventions and Diagnostics
- Cardiovascular Effects of Exercise
- Hemodynamic Monitoring and Therapy
- Cardiac Valve Diseases and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiomyopathy and Myosin Studies
- Pericarditis and Cardiac Tamponade
- Cardiac, Anesthesia and Surgical Outcomes
- Advanced MRI Techniques and Applications
- Cardiac Structural Anomalies and Repair
- Radiation Dose and Imaging
- Acute Myocardial Infarction Research
- Cardiac pacing and defibrillation studies
- Lung Cancer Diagnosis and Treatment
- Cardiovascular Health and Disease Prevention
- Pulmonary Hypertension Research and Treatments
- Venous Thromboembolism Diagnosis and Management
- Advanced X-ray and CT Imaging
- Radiomics and Machine Learning in Medical Imaging
- Elasticity and Material Modeling
St Petersburg University
2018-2025
Saint Petersburg State Pediatric Medical University
2018-2024
City Hospital No. 40
2018-2022
First Pavlov State Medical University of St. Petersburg
2018-2021
Medical Technologies (Czechia)
2019
Mikroelektronika (Czechia)
2017
Leningrad Regional Cancer Center
2012
Institute of Cardiology
2006
Federal Almazov North-West Medical Research Centre
2006
The aim of this study was to assess the prognostic value ABCDE-SE in a prospective, large scale, multicentre, international, effectiveness study. Stress echocardiography (SE) recently upgraded ABCDE protocol: step A, regional wall motion abnormalities; B, B lines; C, left ventricular contractile reserve; D, Doppler-based coronary flow velocity reserve anterior descending artery; and E, electrocardiogram-based heart rate reserve.From July 2016 November 2020, we enrolled 3574 all-comers (age...
Functional testing with stress echocardiography is based on the detection of regional wall motion abnormality two-dimensional and embedded in clinical guidelines. Yet, it under-uses unique versatility technique, ideally suited to describe different functional abnormalities underlying same response during stress. Five parameters converge conceptually methodologically state-of-the-art ABCDE protocol, assessing multiple vulnerabilities ischemic patient. The five steps protocol are (1) step A:...
Heart failure with preserved ejection fraction (HFpEF) is a heterogeneous entity including patients different phenotypes of near normal, and supernormal left ventricular (LV) function. To assess the value resting LV elastance (also known as force) transthoracic echocardiography (TTE) to identify HFpEF phenotypes. In prospective, observational, multicenter study, 2380 were recruited from July 2016 May 2024. Systolic blood pressure (SBP) was measured. We assessed end-diastolic volume (EDV),...
With stress echo (SE) 2020 study, a new standard of practice in imaging was developed and disseminated: the ABCDE protocol for functional testing within beyond CAD. fruit SE 2020, is seed 2030, which articulated 12 projects: 1-SE coronary artery disease (SECAD); 2-SE diastolic heart failure (SEDIA); 3-SE hypertrophic cardiomyopathy (SEHCA); 4-SE post-chest radiotherapy chemotherapy (SERA); 5-Artificial intelligence evaluation (AI-SEE); 6-Environmental echocardiography air pollution (ESTER);...
Background: Lung ultrasound detects pulmonary congestion as B-lines at rest, and more frequently, during exercise stress echocardiography (ESE). Methods: We performed ESE plus lung (4-site simplified scan) in 4392 subjects referred for semi-supine bike 24 certified centers 9 countries. B-line score ranged from 0 (normal) to 40 (severely abnormal). Five different populations were evaluated: control (n=103); chronic coronary syndromes (n=3701); heart failure with reduced ejection fraction...
Resting coronary flow velocity (CFV) in the mid-distal left anterior descending artery can be easily assessed with transthoracic echocardiography. In this observational study, authors sought to assess relationship between resting CFV, CFV reserve (CFVR), and outcome patients chronic syndromes.
Over the past decade, stress echocardiography has evolved from a test for assessing epicardial artery stenosis to comprehensive functional test, targeting multiple cardiovascular parameters. The new approach includes several structured steps: (a) evaluating regional wall motion abnormalities detect or vasospasm; (b) pulmonary congestion and diastolic function via B-lines with lung ultrasound; (c) gauging preload contractile reserve volumetric echocardiography; (d) measuring coronary...
The aim of the study was to assess additive prognostic value coronary flow velocity reserve (CFVR) alongside wall motion analysis during exercise echocardiography in patients with known or suspected artery disease (CAD). In a prospective, single-centre, observational study, we evaluated 689 (449 males; 56 + 9 years) who underwent supine bicycle stress echo (ESE) CFVR evaluation left anterior descending (LAD) by Doppler. ESE positive for regional abnormalities 359 (52%) patients. Mean 1.9 ±...
We aimed to assess feasibility and functional correlates of left atrial volume index (LAVI) changes during exercise stress echocardiography (ESE).ESE on a bike or treadmill was performed in 363 patients with heart failure preserved ejection fraction (HFpEF, n = 173), reduced (HFrEF, 59), hypertrophic cardiomyopathy (HCM, 131). The LAVI stress-rest increase ≥6.8 ml/m2 defined as dilation.LAVI measurements were feasible 100%. did not change HFrEF being at rest 32 (25-45) vs 36 (24-54) ml/m2, P...
The effectiveness trial "Stress echo (SE) 2020" evaluates novel applications of SE in and beyond coronary artery disease. core protocol also includes 4-site simplified scan B-lines by lung ultrasound, useful to assess pulmonary congestion.To provide web-based upstream quality control harmonization reading criteria.60 readers (all previously accredited for regional wall motion, 53 naive) from 52 centers 16 countries 2020 network read a set 20 ultrasound video-clips selected the Pisa lab...
Left atrial (LA) myopathy with paroxysmal and permanent fibrillation (AF) is frequent in chronic coronary syndromes (CCS) but sometimes occult at rest elicited by stress.This study sought to assess LA volume function during stress across the spectrum of AF.In a prospective, multicenter, observational design, we enrolled 3042 patients [age = 64 ± 12; 63.8% male] known or suspected CCS: 2749 were sinus rhythm (SR, Group 1); 191 SR history AF (Group 2); 102 3). All underwent echocardiography...
Background There is a lack of information about the prognostic value high velocity in coronary arteries during echocardiography. The present study was aimed at investigating three-year assessment all patients who were referred for echocardiography examination.Methods prospective comprises 747 consecutive patients. Death, myocardial infarction (MI), acute syndrome (ACS), and/or revascularisation defined as major adverse cardiac events (MACE). Routine added with left main, anterior descending,...