Valentina Lorenzoni
A5025048622- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Advanced MRI Techniques and Applications
- Health Systems, Economic Evaluations, Quality of Life
- Acute Myocardial Infarction Research
- Cardiac pacing and defibrillation studies
- Systemic Lupus Erythematosus Research
- Coronary Interventions and Diagnostics
- Diabetic Foot Ulcer Assessment and Management
- Advanced X-ray and CT Imaging
- Cardiovascular Disease and Adiposity
- Diabetes Treatment and Management
- Pancreatic and Hepatic Oncology Research
- Rheumatoid Arthritis Research and Therapies
- Ultrasound and Hyperthermia Applications
- Ocular Diseases and Behçet’s Syndrome
- Autoimmune and Inflammatory Disorders Research
- Surgical Simulation and Training
- Biosimilars and Bioanalytical Methods
- Colorectal Cancer Surgical Treatments
- Cardiac Structural Anomalies and Repair
- Otitis Media and Relapsing Polychondritis
- Atherosclerosis and Cardiovascular Diseases
- Global Cancer Incidence and Screening
- Pressure Ulcer Prevention and Management
Scuola Superiore Sant'Anna
2016-2025
Azienda Ospedaliero-Universitaria Careggi
2024
University of Florence
2024
University of Foggia
2016-2023
Centre international de recherche sur le cancer
2022
Higher Institute of Management
2021-2022
Centro Cardiologico Monzino
2014-2022
University of Pisa
2018-2021
Azienda Ospedaliera Universitaria Pisana
2016-2021
American Society of Echocardiography
2020
Objective Colorectal cancer (CRC) is the third most common worldwide. The geographical and temporal burden of this provides insights into risk factor prevalence progress in control strategies. We examine current future CRC 185 countries 2020 2040. Methods Data on cases deaths were extracted from GLOBOCAN database for year 2020. Age-standardised incidence mortality rates calculated by sex, country, world region Human Development Index (HDI) countries. Age-specific also estimated. predicted...
BackgroundTracking progress and providing timely evidence is a fundamental step forward for countries to remain aligned with the targets set by WHO eliminate cervical cancer as public health problem (ie, reduce incidence of disease below threshold 4 cases per 100 000 women-years). We aimed assess extent global inequalities in mortality, based on The Global Cancer Observatory (GLOBOCAN) 2020 estimates, including geographical socioeconomic development, temporal aspects.MethodsFor this...
Background— The choice of imaging techniques in patients with suspected coronary artery disease (CAD) varies between countries, regions, and hospitals. This prospective, multicenter, comparative effectiveness study was designed to assess the relative accuracy commonly used for identifying significant CAD. Methods Results— A total 475 stable chest pain intermediate likelihood CAD underwent computed tomographic angiography stress myocardial perfusion by single photon emission tomography or...
Reducing socioeconomic inequalities in cancer is a priority for the public health agenda. A systematic assessment and benchmarking of across many countries over time Europe not yet available.
Accurate risk stratification for patients with non-dilated left ventricular cardiomyopathy (NDLVC) remains challenging due to lack of dedicated clinical trials. This post-hoc analysis aims delineate the arrhythmic and assess incremental value cardiac magnetic resonance (CMR) imaging in DERIVATE (CarDiac MagnEtic Resonance Primary Prevention Implantable CardioVerter DebrillAtor ThErapy) study cohort meeting NDLVC diagnostic criteria. Patients from registry were identified absence (LV)...
To assess the intricate relationship between myocardial infarction (MI) location and size their reciprocal influences on post-infarction left ventricular (LV) remodelling. A cohort of 260 reperfused ST-segment elevation MI patients was prospectively studied with cardiovascular magnetic resonance at 1 week (baseline) 4 months (follow-up). Area risk (AAR) were quantified by T2-weighted late-gadolinium enhancement imaging, respectively. Adverse LV remodelling defined as an increase in...
Systemic lupus erythematosus (SLE) presents with nonspecific signs and symptoms that are also found in other conditions. This study aimed to evaluate manifestations at disease onset compare early SLE those of diseases mimicking SLE.Academic centers Asia, Europe, North America, South America collected baseline data on patients who were referred them during the previous 3 years for possible had a symptom duration <1 year. Clinical serologic compared between diagnosed as having SLE-mimicking...
Hybrid imaging provides a non-invasive assessment of coronary anatomy and myocardial perfusion. We sought to evaluate the added clinical value hybrid in multi-centre multi-vendor setting.Fourteen centres enrolled 252 patients with stable angina intermediate (20-90%) pre-test likelihood artery disease (CAD) who underwent perfusion scintigraphy (MPS), CT angiography (CTCA), quantitative (QCA) fractional flow reserve (FFR). MPS/CTCA images were obtained by 3D image fusion. Blinded core-lab...
Background— We conducted a prospective longitudinal study to investigate the yet unknown clinical significance of myocardial fibrosis in patients with non–ischemic cardiomyopathy without history congestive heart failure (CHF). Methods and Results— At 3 tertiary referral centers, 228 CHF were studied cardiovascular magnetic resonance for late gadolinium enhancement (LGE) detection quantification prospectively followed up median 23 months. The end point was composite cardiac death, onset CHF,...
The aim of this study was to assess the prognostic value ABCDE-SE in a prospective, large scale, multicentre, international, effectiveness study. Stress echocardiography (SE) recently upgraded ABCDE protocol: step A, regional wall motion abnormalities; B, B lines; C, left ventricular contractile reserve; D, Doppler-based coronary flow velocity reserve anterior descending artery; and E, electrocardiogram-based heart rate reserve.From July 2016 November 2020, we enrolled 3574 all-comers (age...
Abstract Background: Oropharyngeal cancer (OPC) is a complex disease whose etiologies, either related to risk factors such as smoking or alcohol, linked HPV infection, are believed be responsible for wide gender and geographical variability. This study depicts the current burden of OPC worldwide. Methods: Estimated new cases, deaths, age-standardized rates (ASR) both incidence mortality in 2020 were obtained from GLOBOCAN database each country across 20 UN-defined world regions by sex. The...
Background Scar burden with late gadolinium enhancement (LGE) cardiac MRI (CMR) predicts arrhythmic events in patients postinfarction single-center studies. However, LGE analysis requires experienced human observers, is time consuming, and introduces variability. Purpose To test whether postinfarct scar CMR can be quantified fully automatically by machines to compare the ability of analyzed humans predict events. Materials Methods This study a retrospective multicenter, multivendor CarDiac...
This study addresses the crucial need for resilient healthcare systems, highlighted by recent global health emergencies such as Ebola and COVID-19 crises. It identifies a significant gap in current literature: lack of practical, actionable frameworks resilience. To bridge this gap, research introduces an innovative framework that blends theoretical resilience concepts with heuristic approaches. framework, rooted principles monitoring, anticipation, recognition, learning, is designed to...
Abstract Objective To provide a baseline comparative assessment of the main epidemiological features prostate cancer in European populations as background for proposed EU screening initiatives. Design Population based study. Setting 26 countries, 19 EU, 1980-2017. National or subnational incidence data were extracted from population registries International Agency Research on Cancer’s Global Cancer Observatory, and mortality World Health Organization. Men aged 35-84 years eligible countries....
Background— The addition of myocardial perfusion (MP) imaging during dipyridamole real-time contrast echocardiography improves the sensitivity to detect coronary artery disease, but its prognostic value predict hard cardiac events in large numbers patients with known or suspected disease remains unknown. Methods and Results— We studied 1252 use followed them for a median 25 months. MP regarding death nonfatal infarction was determined related wall motion (WM), clinical risk factors, rest...
The aim of this study was to determine the prognostic benefit cardiac magnetic resonance (CMR) over transthoracic echocardiography (TTE) in ischemic cardiomyopathy and nonischemic dilated patients evaluated for primary prevention implantable cardioverter-defibrillator therapy.We enrolled 409 consecutive (mean age: 64±12 years; 331 men). All underwent TTE CMR, left ventricle end-diastolic volume, end-systolic ejection fraction (LVEF) were evaluated. In addition, late gadolinium enhancement...
To evaluate the proportion of patients who have successfully withdrawn glucocorticoids (GCs) in a longitudinal cohort with systemic lupus erythematosus (SLE) over period 6 years; to patient characteristics during GC withdrawal relation existing definitions remission and Lupus Low Disease Activity State (LLDAS); occurrence flares after withdrawal.Patients attempted were identified for cohort, following information was assessed attempts: date last disease flare, activity damage ongoing...
The aim of this registry was to evaluate the additional prognostic value a composite cardiac magnetic resonance (CMR)-based risk score over standard-of-care (SOC) evaluation in large cohort consecutive unselected non-ischaemic cardiomyopathy (NICM) patients.In DERIVATE (www.clinicaltrials.gov/registration: RCT#NCT03352648), 1000 (derivation cohort) and 508 (validation NICM patients with chronic heart failure (HF) left ventricular ejection fraction <50% were included. All-cause mortality...