A5019515273- Medical Imaging Techniques and Applications
- Cardiac Imaging and Diagnostics
- Advanced X-ray and CT Imaging
- Advanced MRI Techniques and Applications
- Cardiovascular Function and Risk Factors
- Radiation Dose and Imaging
- Cardiovascular Disease and Adiposity
- Cardiovascular Health and Disease Prevention
- Cardiac Valve Diseases and Treatments
- Radiomics and Machine Learning in Medical Imaging
- AI in cancer detection
- Cerebrovascular and Carotid Artery Diseases
- Lipoproteins and Cardiovascular Health
- Coronary Interventions and Diagnostics
- Medical Image Segmentation Techniques
- Brain Tumor Detection and Classification
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Advanced Radiotherapy Techniques
- Blood Pressure and Hypertension Studies
- Functional Brain Connectivity Studies
- Atrial Fibrillation Management and Outcomes
- Cancer, Lipids, and Metabolism
- Cardiac and Coronary Surgery Techniques
- Lung Cancer Diagnosis and Treatment
Fondazione Toscana Gabriele Monasterio
2014-2023
Regione Toscana
2014-2022
National Research Council
2020-2021
TeraRecon (United States)
2020-2021
Federation of Greek Mariculture
2020
Scan Foundation
2019
Aurelia Hospital
2019
University of Genoa
2009
Czech Academy of Sciences, Institute of Physiology
2005
Istituto di Fisiologia Clinica
2005
Cluster of microcalcifications can be an early sign breast cancer. In this paper, we propose a novel approach based on convolutional neural networks for the detection and segmentation microcalcification clusters. work, used 283 mammograms to train validate our model, obtaining accuracy 99.99% false positive rate 0.005%. Our results show how deep learning could effective tool effectively support radiologists during examination.
Cardiovascular magnetic resonance (CMR) is part of the diagnostic work-up for cardiac amyloidosis (CA). Deep learning (DL) an application artificial intelligence that may allow to automatically analyze CMR findings and establish likelihood CA. 1.5 T was performed in 206 subjects with suspected CA (n = 100, 49% unexplained left ventricular (LV) hypertrophy; n 106, 51% blood dyscrasia light-chain amyloidosis). Patients were randomly assigned training 134, 65%), validation 30, 15%), testing...
<h3>Importance</h3> Although imaging has become a standard tool of modern medicine, its widespread use been paralleled by an increasing cumulative radiation dose to patients despite technological advancements and campaigns calling for better awareness minimization unnecessary exposures. <h3>Objective</h3> To assess patients' knowledge about medical related risks. <h3>Design, Setting, Participants</h3> A survey study hospitals in Italy was conducted; all waiting rooms procedures before...
Percutaneous left atrial appendage occlusion (LAAO) with the Amplatzer Cardiac Plug (ACP) emerged as a valid alternative in patients formal contraindication to oral anticoagulant therapy. Transoesophageal echocardiography (TEE), cardiac computed tomography angiography (CCTA), intracardiac (ICE), and conventional (CCA) are used evaluate LAA diameters. The aim of our study was compare pre- intraprocedural imaging techniques determining correct selection device size, retrospective evaluation...
Abstract Locus Coeruleus (LC) is the main noradrenergic nucleus of brain, which involved in many physiological functions including cognition; its impairment may be crucial neurobiology a variety brain diseases. Coeruleus-Magnetic Resonance Imaging (LC-MRI) allows to identify vivo LC humans. Thus, research teams have been using LC-MRI estimate integrity normal aging and patients affected by neurodegenerative disorders, where my work as biomarker. A number variations between studies exist,...
The locus coeruleus is the main noradrenergic nucleus of brain and often affected in neurodegenerative diseases. Recently, magnetic resonance imaging with specific T1-weighted sequences for neuromelanin has been used to evaluate integrity patients these conditions. In some studies, abnormalities signal have also found healthy controls related ageing. However, this would be at variance recent post-mortem studies showing that not during normal present study aimed evaluating features a...
Abstract Compliance of member States to the Treaty on Non-Proliferation Nuclear Weapons is monitored through nuclear safeguards. The Passive Gamma Emission Tomography (PGET) system a novel instrument developed within framework International Atomic Energy Agency (IAEA) project JNT 1510, which included European Commission, Finland, Hungary and Sweden. PGET used for verification spent fuel stored in water pools. Advanced image reconstruction techniques are crucial obtaining high-quality...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic management is limited by great uncertainty, for both health systems and citizens. Facing this information gap requires a paradigm shift from traditional approaches to healthcare the participatory model of improving health. This work describes design function Doing Risk sElf-assessment Social Support COVID (Dress-COV) system. It aims establish lasting link between user tool; thus, enabling modeling data assess individual...
Arterial hypertension is a main determinant of arterial remodelling and atherosclerosis. Coronary artery calcium score carotid intima-media thickness are recognized indices vascular remodelling. Established biohumoral markers for the diagnosis atherosclerosis still lacking in asymptomatic subjects with hypertension.We aimed to test association plasma N-terminal pro B-type natriuretic peptide concentrations either coronary or hypertensive subjects.We conducted case-control study on 436...
Fractional flow reserve (FFR) estimated from coronary computed tomography angiography (CT-FFR) offers non-invasive detection of lesion-specific ischaemia. We aimed to develop and validate a fast CT-FFR algorithm utilising the Lattice Boltzmann method for blood simulation (LBM CT-FFR).Sixty-four patients with clinically indicated CTA invasive FFR measurement three institutions were retrospectively analysed. was performed using an onsite tool interfacing commercial fluid dynamics cloud-based...
In Europe the 20% of CT scans cover thoracic region. The acquired images contain information about cardiovascular system that often remains latent due to lack contrast in cardiac area. On other hand, enhanced computed tomography (CECT) represents an imaging technique allows easily assess chambers volumes and dynamics. With this work we aim face problem extraction presentation these information, using a deep learning approach with convolutional neural networks. Starting from relevant features...
This article explores how one can lower the injected <sup>18</sup>F-FDG dose while maintaining validity in comparing standardized uptake values (SUVs) between studies. Variations of SUV within each lesion were examined at different acquisition times. <b>Methods:</b> Our protocol was approved by either Human Investigation Committee or Institutional Review Board. All 120 PET datasets acquired continuously for 180 s per bed position list mode and reconstructed to obtain 30-, 60-, 90-, 120-,...
It was the aim of this study to assess pathophysiological, prognostic role aortic regurgitation (AR) in 'mixed pictures' degenerative valve stenoinsufficiency (ASI) by a multimarker clinical approach.We enrolled 112 consecutive surgical19 with pure stenosis (PAS), 39 mild regurgitation, 29 severe and 25 controls annulo-ectatic AR. All underwent complete echocardiography, carotid ultrasound aortic/coronary multislice computed tomography calcium score evaluation. We determined tissue...
Central pulse pressure (PP) has been suggested a better predictor of cardiovascular risk than brachial PP, and its routine noninvasive assessment can be useful for stratification. The present study evaluated the capability radiofrequency-based carotid wall tracking to estimate central PP from distension curves, comparing values as obtained by with those provided applanation tonometry. Furthermore, associations intermediate markers risk, like intima-media thickness (IMT) left ventricular mass...
Several noninvasive vascular biomarkers have been proposed to improve risk stratification for atherothrombotic events. To identify suitable detecting intermediate-risk individuals who might benefit from lipid-lowering treatment in primary prevention, the present study tested association of plasma LDL-cholesterol with coronary artery calcification (CAC) Agatston score, high carotid and femoral intima-media thickness (IMT), low distensibility carotid-femoral pulse-wave velocity 260...