Anna Giulia Pavon
- Cardiac Imaging and Diagnostics
- Cardiac Valve Diseases and Treatments
- Cardiovascular Function and Risk Factors
- Advanced MRI Techniques and Applications
- Cardiac Structural Anomalies and Repair
- Cardiac pacing and defibrillation studies
- Infective Endocarditis Diagnosis and Management
- Coronary Interventions and Diagnostics
- Cardiac Arrhythmias and Treatments
- Cardiac tumors and thrombi
- Cardiovascular Effects of Exercise
- Acute Myocardial Infarction Research
- Pericarditis and Cardiac Tamponade
- Congenital Heart Disease Studies
- Cardiac electrophysiology and arrhythmias
- Cardiomyopathy and Myosin Studies
- Aortic Disease and Treatment Approaches
- Atrial Fibrillation Management and Outcomes
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiovascular Disease and Adiposity
- Cancer Treatment and Pharmacology
- Viral Infections and Immunology Research
- Takotsubo Cardiomyopathy and Associated Phenomena
- Medical Practices and Rehabilitation
- Mechanical Circulatory Support Devices
Ente Ospedaliero Cantonale
2021-2025
Università della Svizzera italiana
2024-2025
University Hospital of Lausanne
2018-2025
Abbott Northwestern Hospital
2024
Inova Fairfax Hospital
2024
Harvard University
2024
McGill University
2024
Epatocentro Ticino
2021-2024
University of Lausanne
2019-2023
Azienda Ospedaliero-Universitaria Careggi
2022-2023
BACKGROUND: Multimodality imaging is currently suggested for the noninvasive diagnosis of cardiac masses. The identification masses’ malignant nature essential to guide proper treatment. We aimed develop a magnetic resonance (CMR)-derived model including mass localization, morphology, and tissue characterization predict malignancy (with histology as gold standard), compare its accuracy versus diagnostic echocardiographic score, evaluate prognostic ability. METHODS: Observational cohort study...
Accurate risk stratification for patients with non-dilated left ventricular cardiomyopathy (NDLVC) remains challenging due to lack of dedicated clinical trials. This post-hoc analysis aims delineate the arrhythmic and assess incremental value cardiac magnetic resonance (CMR) imaging in DERIVATE (CarDiac MagnEtic Resonance Primary Prevention Implantable CardioVerter DebrillAtor ThErapy) study cohort meeting NDLVC diagnostic criteria. Patients from registry were identified absence (LV)...
Mitral annular disjunction (MAD) is an abnormal insertion of the hinge line posterior mitral leaflet on atrial wall: annulus shows a separation or "disjunction" between leaflet-atrial wall junction and crest left ventricle myocardium. This anomaly often observed in patients with myxomatous valve prolapse. The anatomical substrate MAD remains unclear for following reasons: (1) most studies are focused association arrhythmias, rather than pathomorphological aspects MAD; (2) complex anatomic...
Background Patients with mitral valve prolapse (MVP) may develop adverse outcomes even in the absence of regurgitation or left ventricular (LV) dysfunction. Purpose To investigate prognostic value annulus disjunction (MAD) and myocardial fibrosis at late gadolinium enhancement (LGE) cardiac MRI patients MVP without moderate-to-severe LV Materials Methods In this longitudinal retrospective study, 118 144 studies were evaluated between October 2007 June 2020 15 European tertiary medical...
Background Scar burden with late gadolinium enhancement (LGE) cardiac MRI (CMR) predicts arrhythmic events in patients postinfarction single-center studies. However, LGE analysis requires experienced human observers, is time consuming, and introduces variability. Purpose To test whether postinfarct scar CMR can be quantified fully automatically by machines to compare the ability of analyzed humans predict events. Materials Methods This study a retrospective multicenter, multivendor CarDiac...
The aim of this registry was to evaluate the additional prognostic value a composite cardiac magnetic resonance (CMR)-based risk score over standard-of-care (SOC) evaluation in large cohort consecutive unselected non-ischaemic cardiomyopathy (NICM) patients.In DERIVATE (www.clinicaltrials.gov/registration: RCT#NCT03352648), 1000 (derivation cohort) and 508 (validation NICM patients with chronic heart failure (HF) left ventricular ejection fraction <50% were included. All-cause mortality...
We aimed to evaluate the relationship between mitral annular disjunction (MAD) severity and myocardial interstitial fibrosis at left ventricular (LV) base in patients with valve prolapse (MVP), assess association of occurrence arrhythmic events. In MVP, MAD has been associated replacement arrhythmia, but importance remains unknown. this retrospective study, 30 MVP (MVP–MAD) underwent cardiovascular magnetic resonance (CMR) assessment length, late gadolinium enhancement (LGE), basal segments...
The identification of patients with mitral valve prolapse (MVP) presenting high arrhythmic risk remains challenging. Cardiovascular Magnetic Resonance (CMR) feature tracking (FT) may improve stratification. We analyzed the role CMR-FT parameters in relation to incidence complex ventricular arrhythmias (cVA) MVP and annular disjunction (MAD). 42 MAD who underwent 1.5 T CMR were classified as MAD-cVA (n = 23, 55%) case cVA diagnosed on a 24-h Holter monitoring MAD-noVA absence 19, 45%)....
The hepatic response after ST-elevation myocardial infarction (STEMI) may be associated with mortality and morbidity. We aimed to assess the cardio-hepatic axis post-STEMI using cardiovascular magnetic resonance (CMR).
Purpose To use unsupervised machine learning to identify phenotypic clusters with increased risk of arrhythmic mitral valve prolapse (MVP). Materials and Methods This retrospective study included patients MVP without hemodynamically significant regurgitation or left ventricular (LV) dysfunction undergoing late gadolinium enhancement (LGE) cardiac MRI between October 2007 June 2020 in 15 European tertiary centers. The end point was a composite sustained tachycardia, (aborted) sudden death,...
Infectious endocarditis is a life-threatening disease, requiring prompt and accurate diagnosis. The aim of this article to perform systematic review meta-analysis the literature estimate performance fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) for diagnosis native valve (NVE).Selected articles evaluating diagnostic accuracy 18F-FDG PET/CT in patients with suspected NVE, resulting from comprehensive search through PubMed/MEDLINE Cochrane...
Abstract Background Transcatheter edge‐to‐edge repair (TEER) for severe functional mitral regurgitation (FMR) in patients with reduced left ventricular ejection fraction (LVEF) may lead to an acute increase afterload, termed afterload mismatch (AM). This study aimed redefine AM clinically, analyse its determinants, and assess prognostic impact post‐TEER FMR patients. Methods A multicenter case–control was conducted, involving LVEF ≤35% undergoing TEER. defined as the (within 24 h) need...