A5010036129- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Cardiomyopathy and Myosin Studies
- Lysosomal Storage Disorders Research
- Cardiac Valve Diseases and Treatments
- Advanced MRI Techniques and Applications
- Congenital Heart Disease Studies
- Cardiac pacing and defibrillation studies
- Cardiac Structural Anomalies and Repair
- Cardiac electrophysiology and arrhythmias
- Trypanosoma species research and implications
- Studies on Chitinases and Chitosanases
- Coronary Artery Anomalies
- Cardiovascular Issues in Pregnancy
- Cardiac Arrhythmias and Treatments
- ECG Monitoring and Analysis
- Heart rate and cardiovascular health
- Cardiovascular Health and Disease Prevention
- Analog and Mixed-Signal Circuit Design
- Cellular transport and secretion
- Cardiovascular Effects of Exercise
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Heart Failure Treatment and Management
- Viral Infections and Immunology Research
- Blood Pressure and Hypertension Studies
IRCCS Policlinico San Donato
2020-2025
University of Milan
2023-2025
Ospedale Maggiore
2019-2024
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2019-2024
Cytodiagnostics (Canada)
2024
Beth Israel Deaconess Medical Center
2020
Luigi Sacco Hospital
2019
IRCCS Ospedale San Raffaele
2018
Vita-Salute San Raffaele University
2015
University of Bologna
1989
Background Patients with mitral valve prolapse (MVP) may develop adverse outcomes even in the absence of regurgitation or left ventricular (LV) dysfunction. Purpose To investigate prognostic value annulus disjunction (MAD) and myocardial fibrosis at late gadolinium enhancement (LGE) cardiac MRI patients MVP without moderate-to-severe LV Materials Methods In this longitudinal retrospective study, 118 144 studies were evaluated between October 2007 June 2020 15 European tertiary medical...
A small but significant reduction in left ventricular (LV) mass after 18 months of migalastat treatment has been reported Fabry disease (FD). This study aimed to assess the effect on FD cardiac involvement, combining LV morphology and tissue characterisation by magnetic resonance (CMR) with cardiopulmonary exercise testing (CPET).Sixteen treatment-naïve patients (4 women, 46.4±16.2 years) involvement (reduced T1 values CMR and/or hypertrophy) underwent ECG, echocardiogram, troponin T...
The use of apical views focused on the left atrium (LA) has improved accuracy LA volume evaluation by two-dimensional (2D) echocardiography. However, routine cardiovascular magnetic resonance (CMR) volumes still uses standard 2- and 4-chamber cine images ventricle (LV). To investigate potential LA-focused CMR images, we compared maximuml (LAVmax) minimum (LAVmin) volumes, emptying fraction (LAEF), calculated both long-axis with LAEF obtained short-axis stacks covering LA. strain was also...
The presence of mitral annulus disjunction (MAD) has been considered a high-risk feature for sudden cardiac death based on selected study populations. We aimed to assess the prevalence MAD in consecutive patients undergoing clinically indicated cardiovascular magnetic resonance (CMR), its association with ventricular arrhythmias, valve prolapse (MVP), and other CMR features.
Purpose To use unsupervised machine learning to identify phenotypic clusters with increased risk of arrhythmic mitral valve prolapse (MVP). Materials and Methods This retrospective study included patients MVP without hemodynamically significant regurgitation or left ventricular (LV) dysfunction undergoing late gadolinium enhancement (LGE) cardiac MRI between October 2007 June 2020 in 15 European tertiary centers. The end point was a composite sustained tachycardia, (aborted) sudden death,...
Background Time‐resolved three‐directional velocity‐encoded (4D flow) magnetic resonance imaging (MRI) enables the quantification of left ventricular (LV) intracavitary fluid dynamics and energetics, providing mechanistic insight into LV dysfunctions. Before becoming a support to diagnosis patient stratification, this analysis should prove capable discriminating between clearly different derangements. Purpose To investigate potential 4D flow in identifying dynamic energetics derangements...
Abstract Background Anomalous Aortic Origin of Coronary Arteries (AAOCA) is associated with myocardial ischemia and sudden cardiac death, particularly in young athletes. Although inducible investigation generally recommended, there no clear indication the most appropriate stress test, as ECG exercise test presents low diagnostic accuracy. Dobutamine-stress magnetic resonance (dsCMR) has been proposed a promising tool, but its application limited to pediatric populations. Objectives This...
Background: Brugada syndrome (BrS) is considered a purely electrical disease with variable substrates. Variable rates of mechanical abnormalities have been also reported. Whether exists link between and has never previously explored. This investigational physiopathological study aimed to determine the relationship substrate size/location, as exposed by ajmaline provocation, severity abnormalities, assessed cardiac magnetic resonance in patients BrS. Methods: Twenty-four consecutive high-risk...
Abstract Background Multipoint pacing (MPP) may improve clinical outcomes in patients with cardiac resynchronization therapy defibrillators (CRT‐D), but its impact on battery longevity a real‐world population has not been investigated large trials. Objective Compare projected CRT‐D and without MPP during long‐term follow‐up. Methods The Italian registry multipoint left ventricular (IRON‐MPP) is prospective, multicenter of implanted MPP‐capable devices. Projected follow‐up was compared for...