A5018171696- Heart Failure Treatment and Management
- Cardiovascular Function and Risk Factors
- Acute Myocardial Infarction Research
- Cardiac Imaging and Diagnostics
- Acute Kidney Injury Research
- Cardiovascular and exercise physiology
- Viral Infections and Immunology Research
- Cardiac Structural Anomalies and Repair
- Cardiovascular Effects of Exercise
- Cardiac Arrest and Resuscitation
- Cardiovascular Disease and Adiposity
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Erythropoietin and Anemia Treatment
- Dialysis and Renal Disease Management
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Healthcare Systems and Public Health
- COVID-19 Clinical Research Studies
- Extracellular vesicles in disease
- Antiplatelet Therapy and Cardiovascular Diseases
- Mechanical Circulatory Support Devices
- Atrial Fibrillation Management and Outcomes
- Diabetes Treatment and Management
- Pericarditis and Cardiac Tamponade
- Heart Rate Variability and Autonomic Control
- Cardiac Valve Diseases and Treatments
Centro Cardiologico Monzino
2016-2025
University of Milan
2010-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2018-2024
University of Padua
2024
University of Perugia
2024
University of Cagliari
2024
University of Trieste
2023-2024
Ospedali Riuniti di Ancona
2023
Azienda Ospedaliero Universitaria Ospedali Riuniti
2023
Ospedali Riuniti Umberto I
2023
Patients with acute myocardial infarction undergoing primary angioplasty are at high risk for contrast-medium-induced nephropathy because of hemodynamic instability, the need a volume contrast medium, and lack effective prophylaxis. We investigated antioxidant N-acetylcysteine prevention in patients angioplasty.We randomly assigned 354 consecutive to one three groups: 116 were standard dose (a 600-mg intravenous bolus before 600 mg orally twice daily 48 hours after angioplasty), 119 double...
Nephropathy induced by exposure to radiocontrast agents, a possible complication of percutaneous coronary interventions, is associated with significant in-hospital and long-term morbidity mortality. Patients preexisting renal failure are at particularly high risk. We investigated the role hemofiltration, as compared isotonic-saline hydration, in preventing contrast-agent-induced nephropathy patients failure.We studied 114 consecutive chronic (serum creatinine concentration, >2 mg per...
Background: Contrast-induced nephropathy (CIN) frequently occurs in patients with acute ST-segment elevation myocardial infarction (STEMI) who are undergoing primary percutaneous coronary intervention, and CIN is associated a more complicated clinical course increased mortality. Objective: To investigate the association between absolute weight- creatinine-adjusted contrast volume, incidence, outcome era of mechanical reperfusion STEMI. Design: Prospective, observational study. Setting: A...
There is controversy about the outcome of patients with acute myocarditis (AM), and data are lacking on how admitted suspected AM managed. We report characteristics, in-hospital management, long-term based a retrospective multicenter registry from 19 Italian hospitals.A total 684 recent onset symptoms (<30 days) were screened between May 2001 February 2017. Patients >70 years age those >50 without coronary angiography excluded. The final study population comprised 443 (median age, 34 years;...
Acute myocarditis (AM) is thought to be a rare cardiovascular complication of COVID-19, although minimal data are available beyond case reports. We aim report the prevalence, baseline characteristics, in-hospital management, and outcomes for patients with COVID-19-associated AM on basis retrospective cohort from 23 hospitals in United States Europe.A total 112 suspected 56 963 hospitalized COVID-19 were evaluated between February 1, 2020, April 30, 2021. Inclusion criteria hospitalization...
Objective: To evaluate the clinical and prognostic relevance of acute kidney injury (AKI) in setting ST-elevation myocardial infarction (STEMI) complicated by cardiogenic shock (CS). Design: Prospective study. Setting: Single-center study, 13-bed intensive cardiac care unit at a University Cardiological Center. Patients: Ninety-seven consecutive STEMI patients with CS admission, undergoing intra-aortic balloon pump (IABP) support primary percutaneous coronary intervention (PCI)....
OBJECTIVE Acute hyperglycemia is a powerful predictor of poor prognosis in acute myocardial infarction (AMI), particularly patients without diabetes. This emphasizes the importance an glycemic rise rather than glycemia level at admission alone. We investigated AMI whether combined evaluation and chronic levels, as compared with alone, may have better prognostic value. RESEARCH DESIGN AND METHODS prospectively measured estimated average glucose levels (mg/dL) by following formula: [(28.7 ×...
During the COVID-19 pandemic, use of protective masks has been essential to reduce contagions. However, public opinion is that there an associated subjective shortness breath. We evaluated cardiorespiratory parameters at rest and during maximal exertion highlight any differences with masks. 12 healthy subjects performed three identical cardiopulmonary exercise tests, one without wearing a mask, surgical mask filtering face piece particles class 2 (FFP2) mask. Dyspnoea was assessed using Borg...
Deficiency in 25-hydroxyvitamin D (25[OH]D), the main circulating form of vitamin blood, could be involved pathogenesis acute coronary syndromes (ACS). To date, however, possible prognostic relevance 25 (OH)D deficiency ACS patients remains poorly defined. The purpose this prospective study was to assess association between levels, at hospital admission, with in-hospital and 1-year morbidity mortality an unselected cohort patients.We measured 814 presentation. Vitamin serum levels >30 ng/mL...
In heart failure (HF) iron deficiency (ID) is frequently observed and represents a major mortality risk factor. Purpose of this study was to evaluate the correlation between ID in cohort 661 consecutive patients hospitalized for HF worsening.Patients were grouped: (i)according presence(+)/absence(-) anaemia (A) defined following World Health Organization (WHO) European Society Cardiology (ESC)-American College Cardiology/American Heart Association/HF society America (ACC/AHA/HFSA)...
Blockade of bradykinin breakdown and enhancement prostaglandin release probably participate in the antihypertensive activity angiotensin converting enzyme (ACE) inhibitors. Cyclooxygenase blockers may attenuate efficacy ACE inhibitors by interfering with synthesis, patients taking aspirin not benefit from inhibition. This study was designed to evaluate incidence counteractive phenomenon define minimal dosage that causes an antagonistic effect.These were 26 mild moderate hypertension (group...