A5056507543- Cardiac Imaging and Diagnostics
- Advanced X-ray and CT Imaging
- Radiation Dose and Imaging
- Aortic aneurysm repair treatments
- Medical Imaging Techniques and Applications
- Cardiac Valve Diseases and Treatments
- Aortic Disease and Treatment Approaches
- Advanced MRI Techniques and Applications
- Coronary Interventions and Diagnostics
- Cardiovascular Function and Risk Factors
- Cardiovascular Disease and Adiposity
- Cardiac tumors and thrombi
- MicroRNA in disease regulation
- Adrenal and Paraganglionic Tumors
- Lipoproteins and Cardiovascular Health
- Cancer-related molecular mechanisms research
- Cerebrovascular and Carotid Artery Diseases
- Circular RNAs in diseases
- Cardiovascular Effects of Exercise
- Coronary Artery Anomalies
- Renal and Vascular Pathologies
- Kawasaki Disease and Coronary Complications
- dental development and anomalies
- Chemokine receptors and signaling
- Cholesterol and Lipid Metabolism
SDN Istituto di Ricerca Diagnostica e Nucleare
2019-2023
Istituti di Ricovero e Cura a Carattere Scientifico
2019-2023
Spectral Photon-Counting Computed Tomography (SPCCT) represents a groundbreaking advancement in X-ray imaging technology. The core innovation of SPCCT lies its photon-counting detectors, which can count the exact number incoming x-ray photons and individually measure their energy. first part this review summarizes key elements technology, such as energy binning, weighting, material decomposition. Its energy-discriminating ability to increase contrast between different tissues, elimination...
Atherosclerotic plaque buildup in the coronary and carotid arteries is pivotal onset of acute myocardial infarctions or cerebrovascular events, leading to heightened levels illness death. Atherosclerosis a complex multistep disease, beginning with deposition low-density lipoproteins arterial intima culminating rupture. Modern technology favors non-invasive imaging techniques assess atherosclerotic offer insights beyond mere artery stenosis. Among these, computed tomography stands out for its...
Circulating biomarkers available in clinical practice do not allow to stratify patients with coronary heart disease (CHD) prior the onset of a clinically relevant event. We evaluated methylation status specific genomic segments and gene expression peripheral blood undergoing Cardiac Computed Tomography (CCT) for CHD (n = 95). choose investigate cholesterol metabolism. Methylation low density lipoprotein receptor (LDLR), sterol regulatory element-binding factor 2 (SREBF2) ATP-binding cassette...
Abstract Optimal medical treatment in patients with stable coronary artery disease reduced morbidity and mortality but left a substantial residual risk of progression events. According to recent evidence, insulin resistance or pre-diabetes together elevated levels triglycerides, low functionality high-density lipoprotein cholesterol, often associated chronic inflammatory state, are deemed be relevant components cardiometabolic vascular risk. In the present project we aim at discovering...
For decades, the main imaging tool for multiple myeloma (MM) patient’s management has been conventional skeleton survey. In 2014 international working group defined advantages of whole-body low dose computed tomography (WBLDCT) as a gold standard, among modalities, bone disease assessment and subsequently implemented this technique in MM diagnostic workflow. The aim study is to investigate, 30 patients with new diagnosis MM, radiation (CT index, dose-length product, effective dose),...
Four-dimensional (4D) flow cardiac magnetic resonance (CMR) represents an emerging technique for non-invasive evaluation of the aortic flow. The aim this study was to investigate a 4D-flow CMR sequence assessment thoracic aorta comparing different vendors and fields MR scanner in fifteen healthy volunteers.CMR performed on three MRI scanners: one at 1.5 T two 3 T. Flow parameters planar wall shear stress (WSS) were extracted from six transversal planes along full by operators. Inter-vendor...
To analyze the relationship between aortic measures and biometric parameters in a large cohort of consecutive patients undergoing computed tomography coronary angiography.1170 (717 men/453 women) performing angiography for evaluation were retrospectively evaluated. Aortic diameters areas measured at reproducible anatomic landmarks, perpendicular to axis vessel, level root (AoR), sinotubular junction (STJ), tubular ascending aorta (TAo). Biometric cardiovascular risk factors recorded.The...
Cardiac paragangliomas (PGLs) are rare extra-adrenal tumors that arise from chromaffin cells of the sympathetic ganglia. PGLs often diagnosed incidentally, in absence symptoms, or with symptoms related to cardiovascular dysfunction. computed tomography (CCT) and cardiac magnetic resonance (CMR) can be used accurately determine lesion morphology position as well providing detailed tissue characterization. A multimodal imaging approach, not yet standardized, could useful either diagnosis...
Coronary artery disease (CAD) is a long-term inflammatory process, with atherosclerosis as its underlying pathophysiological mechanism. Endothelial dysfunction the first step towards atherosclerosis, where damaged endothelial cells release large amounts of pro-inflammatory cytokines and mediators, thus promoting vascular inflammation progression. However, correlation between serum CAD severity remains to be defined. Serum samples from patients performing cardiac computed tomography for...
Abstract Rationale: Unlike invasive coronary angiography and echocardiography, cardiac computed tomography (CCT) magnetic resonance (CMR) imaging allow a artery fistula (CAF) comprehensive evaluation focusing on both myocardial findings. Patient concerns: We present the case of an asymptomatic patient suspected for CAF referred to our structure cardiovascular evaluation. Diagnosis: The was diagnosed without disease basis CMR CCT. Interventions: underwent after which medical staff decided not...
Abstract Introduction: Single coronary artery is a rare condition characterized by the origin of that supplies entire heart from single ostium. Patient concerns: A 45-year-old woman with an altered exercise testing was addressed to computed tomography angiography (CTCA) rule out disease (CAD). Diagnosis: CTCA examination showed absence right (RCA). The left anterior descending and circumflex (LCX) presented regular course LCX provided posterior interventricular posterolateral artery....