- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Cardiac Valve Diseases and Treatments
- Coronary Interventions and Diagnostics
- Cardiac pacing and defibrillation studies
- Cardiac Structural Anomalies and Repair
- Atrial Fibrillation Management and Outcomes
- Heart Failure Treatment and Management
- Acute Myocardial Infarction Research
- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Cardiovascular and exercise physiology
- Antiplatelet Therapy and Cardiovascular Diseases
- Infective Endocarditis Diagnosis and Management
- Cardiovascular Effects of Exercise
- Venous Thromboembolism Diagnosis and Management
- Cardiomyopathy and Myosin Studies
- Pulmonary Hypertension Research and Treatments
- Heart Rate Variability and Autonomic Control
- Cardiac, Anesthesia and Surgical Outcomes
- Aortic aneurysm repair treatments
- Mechanical Circulatory Support Devices
- Blood Pressure and Hypertension Studies
- Viral Infections and Immunology Research
- Cardiac tumors and thrombi
IRCCS Ospedale San Raffaele
2015-2025
Vita-Salute San Raffaele University
2016-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2015-2025
Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele
2014-2024
Istituto Nazionale per le Ricerche Cardiovascolari
2024
San Raffaele University of Rome
2014-2023
Alessandro Manzoni Hospital
2023
Parallax Research (United States)
2021
Mylan (Switzerland)
2021
Institute of Molecular Bioimaging and Physiology
2017
Abstract Aims To evaluate the impact of COVID-19 pandemic on patient admissions to Italian cardiac care units (CCUs). Methods and Results We conducted a multicentre, observational, nationwide survey collect data for acute myocardial infarction (AMI) at CCUs throughout 1 week period during outbreak, compared with equivalent in 2019. observed 48.4% reduction AMI 2019 (P < 0.001). The was significant both ST-segment elevation [STEMI; 26.5%, 95% confidence interval (CI) 21.7–32.3; P =...
Aims The addition of trimetazidine to standard treatment has been shown improve left ventricular (LV) function in patients with heart failure. aim this study is non-invasively assess, by means vivo31P-magnetic resonance spectroscopy (31P-MRS), the effects on LV cardiac phosphocreatine and adenosine triphosphate (PCr/ATP) ratio
Previously undiagnosed diabetes, impaired glucose tolerance, and insulin resistance are common in patients with acute myocardial infarction coronary heart disease (CHD) might be involved early restenosis after stent implantation. To evaluate whether markers of syndrome, including leptin, endothelial dysfunction related to increased rate restenosis, we studied nondiabetic CHD successful stenting.Both undergoing stenting (120 patients) control subjects (58 were submitted an oral tolerance test...
OBJECTIVE: The purpose of this study was (a) to whether a folate and vitamin B12 treatment, aimed at decreasing homocysteine levels, might ameliorate insulin resistance endothelial dysfunction in patients with metabolic syndrome according the National Cholesterol Education Program-Adult Treatment Panel-III criteria (b) evaluate whether, under these conditions, there is relationship between hyperhomocysteinemia resistance. DESIGN AND METHODS: A double-blind, parallel, identical placebo-drug,...
The effects of dopamine on arteries are different depending the dose, route administration, and receptor population. Its administration can cause vasodilation by stimulation dopaminergic receptors, vasoconstriction alpha-adrenergic serotonergic even spasm cerebral when given intracisternally in dogs. ability to provoke coronary was assessed 18 patients with active vasospastic angina whom this amine infused at rates 5, 10, 15 micrograms/kg/min for periods 5 min each. 12-lead electrocardiogram...
<h3>Objective</h3> Trimetazidine may have beneficial effects on left ventricular (LV) function in patients with systolic heart failure. The authors assessed whether long-term addition of trimetazidine to conventional treatment could improve, along LV function, resting whole body energy metabolism chronic <h3>Design</h3> Single blind randomised study. <h3>Setting</h3> University Hospital. <h3>Patients</h3> 44 failure receiving full medical treatment. <h3>Interventions</h3> Indirect...
Objective Pulmonary congestion is the main cause of hospital admission in patients with heart failure (HF). Lung ultrasound (LUS) a useful tool to identify subclinical pulmonary congestion. We evaluated usefulness LUS addition physical examination (PE) management outpatients HF. Methods In this randomised multicentre unblinded study, chronic HF and optimised medical therapy were two groups: ‘PE+LUS’ group undergoing PE ‘PE only’ group. Diuretic was modified according findings PE,...
Background Acute chest pain with mild troponin rise and inconclusive diagnosis after clinical evaluation represents a diagnostic challenge. Triple-rule-out (TRO) CT may exclude coronary artery disease (CAD), as well acute aortic syndrome pulmonary embolism, but cannot help identify other causes of myocardial injury. Purpose To investigate the value comprehensive protocol including both an angiographic late contrast enhancement (LCE) scan in participants troponin-positive pain. Materials...