- Cardiac Valve Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Cardiovascular Function and Risk Factors
- Aortic Disease and Treatment Approaches
- Cardiac Imaging and Diagnostics
- Atrial Fibrillation Management and Outcomes
- Cardiac pacing and defibrillation studies
- Venous Thromboembolism Diagnosis and Management
- Cardiac Structural Anomalies and Repair
- Mechanical Circulatory Support Devices
- Cardiac Arrhythmias and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac tumors and thrombi
- Vascular Procedures and Complications
- Urological Disorders and Treatments
- Cardiovascular Effects of Exercise
- Cardiac electrophysiology and arrhythmias
- Cardiac and Coronary Surgery Techniques
- Aortic aneurysm repair treatments
- Transplantation: Methods and Outcomes
- Anatomy and Medical Technology
- Coronary Interventions and Diagnostics
- Ureteral procedures and complications
- Pelvic floor disorders treatments
- Cardiovascular Disease and Adiposity
Erasmus MC
2018-2025
Erasmus University Rotterdam
2021-2023
Institut Universitaire de Cardiologie et de Pneumologie de Québec
2022
Isala
2015
KU Leuven
2005-2006
Background: The potential benefit of transcatheter aortic valve replacement (TAVR) in patients with nonsevere stenosis (AS) and heart failure is controversial. This study aimed to assess outcomes low-gradient AS (LGAS) reduced left ventricular ejection fraction undergoing TAVR or medical management. Methods: Patients for LGAS (<50%) were included a multinational registry. True-severe (TS-LGAS) pseudo-severe (PS-LGAS) classified according computed tomography-derived calcification...
Transaxillary transcatheter aortic valve implantation (TAx-TAVI) is the most used alternative access when severe iliofemoral disease renders transfemoral infeasible. Compared to surgical transaxillary access, a true percutaneous approach using vascular closure devices (VCD) has advantages but can be challenging. Herein, we describe impact of "unilateral, suture-mediated, dry-closure technique" on safety and efficacy in patients undergoing TAx-TAVI. A total 77 TAx-TAVI were categorized into...
New permanent pacemaker implantation (new-PPI) remains a compelling issue after Transcatheter Aortic Valve Replacement (TAVR). Previous studies reported the relationship between short MS length and new-PPI post-TAVR with self-expanding THV. However, this has not been investigated in different currently available Therefore, aim of study was to investigate association membranous septum (MS)-length TAVR Heart (THV)-platforms.We included patients successful TAVR-procedure an analyzable...
Background Little is known about the impact of transcatheter mitral valve edge-to-edge repair on changes in left ventricular ejection fraction (LVEF) and effect an acute reduction LVEF prognosis. We aimed to assess after for both primary secondary regurgitation (PMR SMR, respectively), identify rates predictors reduction, estimate its Methods Results In this international multicenter registry, patients with PMR SMR undergoing were included. assessed (LVEFR), defined as relative decrease >15%...
In aortic stenosis, valvulo-arterial impedance (Zva) estimates the overall left ventricular afterload (valve and arterial component). We investigated association of Zva (≥5 versus <5 mm Hg mL-1 m-2) on quality life (QOL) exercise performance (EP) ≥1 year after transcatheter valve replacement (TAVR).The study population consists 250 TAVR patients in whom baseline follow-up QOL was prospectively assessed using EuroQOL-5-dimensions instruments; EP 192 who survived questionnaires related to...
Abstract Background Transcatheter aortic valve implantation (TAVI) brings symptom relief and improvement in health-related quality of life (HRQoL) the majority patients treated for symptomatic, severe stenosis. However, there is a substantial group that do not benefit from TAVI. The aim this study to investigate impact frailty on HRQoL 1 year after Methods TAVI Care & Cure Program an ongoing, prospective, observational including referred our institution. A comprehensive geriatric...
Aims: The aim of this study was to investigate the total amount, size and heterogeneity debris captured among different transcatheter valve types while repositioning. Methods results: A 328 patients who underwent aortic implantation (TAVI) with SENTINEL cerebral embolic protection (CEP) at our centre were eligible. Histopathological semiquantitative analysis performed data entered into prospective database. TAVI either Evolut R/PRO (N=123), SAPIEN 3 (N=113) or Lotus (N=92). Capture occurred...
•Transcatheter treatment of FMR is a subject debate.•Proportionality EROA to LV volumes could influence the outcome TEER.•Disproportionate mitral regurgitation showed greater reduction after TEER.•A substantial part initial deteriorated during follow-up.•Clinical outcomes at 2 years did not differ between different proportionality groups. BackgroundFunctional (FMR) can be subclassified on basis its relative left ventricular (LV) volume and function, indicating potential differences in...
The axillary artery is an alternative route for patients with comorbidities and unfavorable femoral arteries who need transcatheter aortic valve replacement (TAVR). Simplified trans-axillary (TAx-TAVR) implies a completely percutaneous approach under local anesthesia arteriotomy closure vascular techniques. Herein, we report on early experience simplified TAx-TAVR anesthesia. We enrolled all consecutive underwent in our center. Main study parameter was the incidence of access related major...
The MANTA vascular closure device (VCD) is dedicated to large bore access and associated with favorable results in selected study populations. Anatomical predictors for site complications are lacking.To evaluate a real-world population identify complications.All patients undergoing transfemoral transcatheter aortic valve replacement (TAVR) between January 2016 May 2020 were included. Baseline characteristics collected, pre-procedural computed tomography post-deployment femoral angiograms...
Selecting patients with a high chance of endured benefit from transcatheter aortic valve implantation (TAVI) is becoming relevant changing indications and increasing number TAVI being performed. The aim our study was to investigate the association multidimensional prognostic index (MPI) based on comprehensive geriatric assessment (CGA) survival. Care & Cure program prospective, observational registry referred for at Erasmus MC University Medical Center. Consecutive who underwent complete...
Obtaining optimal pulmonary vein (PV) occlusion with the endoscopic laser balloon ablation system (EAS) can be difficult, hypothetically influenced by PV geometry. The aim of this study was to determine impact orientation on atrial fibrillation (AF)-free survival after isolation (PVI) using EAS.Forty-three patients undergoing a single EAS PVI were included. Left electrocardiogram -triggered computed tomography performed in all prior PVI. Of four PVs, at insertion left atrium measured both...
The mean age of transcatheter aortic valve implantation (TAVI) patients is steadily decreasing.The aim the study was to describe characteristics, indications for and outcomes TAVI in <70 years old.All undergoing (n=8,626) from 18 participating centres between January 2007 June 2020 were stratified by (</>70). For <70, extracted Heart Team discussions baseline characteristics mortality compared two groups.Overall, 640 (7.4%) (9.1% during 2018-2020, p<0.001); 65.0±2.3 years. younger more often...