Mirjam G. Wild
A5033654337- Cardiac Valve Diseases and Treatments
- Cardiovascular Function and Risk Factors
- Infective Endocarditis Diagnosis and Management
- Cardiac Structural Anomalies and Repair
- Pulmonary Hypertension Research and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Congenital Heart Disease Studies
- Aortic Disease and Treatment Approaches
- Orthopaedic implants and arthroplasty
- Cardiac Imaging and Diagnostics
- Venous Thromboembolism Diagnosis and Management
- Muscle Physiology and Disorders
- Diagnosis and Treatment of Venous Diseases
- Thyroid Cancer Diagnosis and Treatment
- Shoulder Injury and Treatment
- Cardiovascular Health and Disease Prevention
- Cardiovascular Disease and Adiposity
- Mechanical Circulatory Support Devices
- Hip disorders and treatments
Universitäts-Herzzentrum Freiburg-Bad Krozingen
2023-2025
LMU Klinikum
2021-2024
Ludwig-Maximilians-Universität München
2021-2024
University of Freiburg
2024
University Medical Center Freiburg
2024
University Hospital of Bern
2021-2023
University of Bern
2021-2023
German Centre for Cardiovascular Research
2022
Instituto Nacional de Cardiologia
2005
University of Milan
2005
Aims Data on the prognostic impact of residual tricuspid regurgitation (TR) after transcatheter edge‐to‐edge repair (T‐TEER) are scarce. The aim this analysis was to evaluate 2‐year survival and symptomatic outcomes patients in relation TR T‐TEER. Methods results Using large European Registry Transcatheter Repair for Tricuspid Regurgitation (EuroTR registry) we investigated all‐cause mortality New York Heart Association (NYHA) functional class at follow‐up. study further identified...
Tricuspid regurgitation (TR) has a poor prognosis and limited treatment options is frequently accompanied by right ventricular (RV) dysfunction. Transcatheter tricuspid valve interventions (TTVI) to reduce TR have been shown be safe feasible with encouraging early results. Patient selection for TTVI remains challenging, the role of function being unknown.The aims this study were 1) investigate survival in TTVI-treated patient population conservatively treated population, 2) evaluate outcome...
Early studies of the Tendyne transcatheter mitral valve replacement (TMVR) showed promising results in a small selective cohort. The authors present 1-year data from currently largest commercial, real-world cohort originating investigator-initiated TENDER (Tendyne European Experience) registry. All patients registry eligible for follow-up were included. primary safety endpoint was cardiovascular mortality. Primary performance reduction regurgitation (MR) up to 1 year. Among 195 undergoing...
Tricuspid transcatheter edge-to-edge repair (T-TEER) has emerged as a treatment option for patients with severe tricuspid regurgitation (TR). However, randomized trials have not shown survival benefit, possibly because of the inclusion in an early or too advanced disease stage. The authors sought to investigate association between stage and outcomes following T-TEER. In total, 1,885 significant TR were analyzed, including 585 conservatively treated individuals 1,300 who received Patients...
Abstract Aims The impact of sexuality in patients with significant tricuspid regurgitation (TR) undergoing transcatheter valve intervention (TTVI) is unknown. aim this study was to investigate sex-specific outcomes TR treated TTVI vs. medical therapy alone. Methods and results Transcatheter Tricuspid Valve Therapies (TriValve) registry collected data on from 24 centres who underwent 2016 2021. A control cohort formed by medically managed ≥severe isolated diagnosed 2015–18. primary endpoint...
Background Little is known about the impact of transcatheter mitral valve edge-to-edge repair on changes in left ventricular ejection fraction (LVEF) and effect an acute reduction LVEF prognosis. We aimed to assess after for both primary secondary regurgitation (PMR SMR, respectively), identify rates predictors reduction, estimate its Methods Results In this international multicenter registry, patients with PMR SMR undergoing were included. assessed (LVEFR), defined as relative decrease >15%...
Guideline-directed medical therapy (GDMT), based on the combination of beta-blockers (BB), renin-angiotensin system inhibitors (RASI), and mineralocorticoid receptor antagonists (MRA), is known to have a major impact outcome patients with heart failure reduced ejection fraction (HFrEF). Although GDMT recommended prior mitral valve transcatheter edge-to-edge repair (M-TEER), not all tolerate it. We studied association prescription survival in HFrEF undergoing M-TEER for secondary...
Right ventricular dysfunction (RVD), as expressed by right to pulmonary artery coupling, has recently been identified a strong outcome predictor in patients undergoing mitral valve edge-to-edge repair (M-TEER) for secondary regurgitation (MR). The aim of this study was define RVD M-TEER primary MR (PMR) and evaluate its impact on procedural reduction, symptomatic development 2-year all-cause mortality.This multicentre included PMR at nine international centres. cohort divided into derivation...
The impact of the cardio-hepatic syndrome (CHS) on outcomes in patients undergoing mitral valve transcatheter edge-to-edge repair (M-TEER) for relevant regurgitation (MR) is unknown. objectives this study were three-fold: (i) to characterize pattern hepatic impairment, (ii) investigate prognostic value CHS, and (iii) evaluate changes function after M-TEER.Hepatic impairment was quantified by laboratory parameters liver function. In accordance with existing literature, two types CHS...
Zusammenfassung Die Mehrzahl der in Praxis und Klinik behandelten Patient*innen mit einer funktionellen Trikuspidalklappeninsuffizienz (TI) weist eine Vielzahl kardialer extrakardialer Komorbiditäten auf. Einerseits lässt sich dies auf die an Ursachen zurückführen, zur Entstehung TI beitragen können. Diese umfassen neben linksseitigen myokardialen valvulären Pathologien auch pulmonale intrinsische rechtsventrikuläre Erkrankungen sowie das Vorhofflimmern. Andererseits kennzeichnet...
Abstract Aims Although several treatment options are available for patients with severe mitral regurgitation (MR), a significant proportion of remain ineligible any valve (MV) intervention. We aimed to analyze the phenotypic characteristics surgical high-risk MV interventions using an unsupervised clustering approach. Methods and Results Between 2014 2022, CHOICE-MI registry included 984 MR undergoing screening transcatheter replacement at 33 international sites. For this study, only failure...
Objectives The objective of this study was to characterize a population patients with severe tricuspid regurgitation (TR) evaluated at tertiary care center, assess mid-term clinical outcomes, and identify prognostic factors. Background impact TR on morbidity mortality is increasingly recognized. Clinical characteristics long-term outcomes suffering from remain unclear. Methods This retrospective observational single-center hospital including echocardiographic diagnosis between January 2017...