A5013997692- Cardiac Valve Diseases and Treatments
- Coronary Interventions and Diagnostics
- Acute Myocardial Infarction Research
- Cardiac Imaging and Diagnostics
- Cardiac Structural Anomalies and Repair
- Antiplatelet Therapy and Cardiovascular Diseases
- Mechanical Circulatory Support Devices
- Infective Endocarditis Diagnosis and Management
- Cardiovascular Function and Risk Factors
- Cardiac pacing and defibrillation studies
- Cardiovascular Disease and Adiposity
- Peripheral Artery Disease Management
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Atherosclerosis and Cardiovascular Diseases
- Cardiac, Anesthesia and Surgical Outcomes
- Blood Pressure and Hypertension Studies
- Atrial Fibrillation Management and Outcomes
- Cerebrovascular and Carotid Artery Diseases
- Systemic Lupus Erythematosus Research
- Central Venous Catheters and Hemodialysis
- Venous Thromboembolism Diagnosis and Management
- Vascular Procedures and Complications
- Aortic Thrombus and Embolism
- Cardiac Arrest and Resuscitation
- Cardiac Health and Mental Health
MedStar Washington Hospital Center
2024-2025
Kaplan Medical Center
2016-2025
Georgetown University
2025
Washington Hospital
2024
MedStar Health
2024
Hebrew University of Jerusalem
2019-2023
Weatherford College
2021
The aim of this study was to evaluate the outcome transcatheter mitral valve repair (TMVr) in patients with cardiogenic shock and significant regurgitation (MR). Patients severe MR have a poor prognosis setting conventional medical therapy. Because its favorable safety profile, TMVr is being increasingly used as an acute therapy population, though efficacy remains unknown. A multicenter, collaborative, patient-level analysis conducted. moderate (3+) or (4+) who were not surgical candidates...
Severe mitral regurgitation (MR) following acute myocardial infarction (MI) is associated with high mortality rates and has inconclusive recommendations in clinical guidelines. We aimed to report the international experience of patients secondary MR MI compare outcomes those treated conservatively, surgically, percutaneously.Retrospective registry consecutive at least moderate-to-severe 21 centres North America, Europe, Middle East. The included conservatively having surgical valve repair or...
Background Coronary microvascular dysfunction (CMD), which mimics symptoms of obstructive coronary artery disease, has significant prognostic implications. While epicardial adipose tissue normally a protective role, increased is associated with inflammation and may contribute to CMD. However, direct correlation remains unclear. We aimed investigate this association. Methods Results The CMDR (Coronary Microvascular Disease Registry) prospective, 2‐center registry that enrolling patients...
ABSTRACT Background Cangrelor is an intravenous P2Y12 receptor antagonist that exerts rapid and potent antiplatelet effects. It associated with a reduction in the indcidence of ischemic events patients acute coronary syndrome (ACS) undergoing percutaneous intervention (PCI). Aims The aim our study was to investigate racial disparities their impact on outcomes among ACS who were treated cangrelor during PCI. Methods We reviewed data PCI at center from 2018 2023 divided between African...
Abstract Objectives To assess outcomes in patients with acute mitral regurgitation (MR) following myocardial infarction (AMI) who received percutaneous valve repair (PMVR) the MitraClip device and to compare of developed cardiogenic shock (CS) those did not (non‐CS). Background Acute MR after AMI may lead CS is associated high mortality. Methods This registry analyzed were treated at 18 centers within eight countries between January 2016 February 2020. Patients stratified into non‐CS groups....
Myocarditis and pericarditis are potential post-acute cardiac sequelae of COVID-19 infection, arising from adaptive immune responses. We aimed to study the incidence myocarditis pericarditis. Retrospective cohort 196,992 adults after infection in Clalit Health Services members Israel between March 2020 January 2021. Inpatient diagnoses were retrieved day 10 positive PCR. Follow-up was censored on 28 February 2021, with minimum observation 18 days. The control 590,976 at least one negative...
Background Little is known about the impact of transcatheter mitral valve edge-to-edge repair on changes in left ventricular ejection fraction (LVEF) and effect an acute reduction LVEF prognosis. We aimed to assess after for both primary secondary regurgitation (PMR SMR, respectively), identify rates predictors reduction, estimate its Methods Results In this international multicenter registry, patients with PMR SMR undergoing were included. assessed (LVEFR), defined as relative decrease >15%...
C-C motif chemokine ligand 24 (CCL24) is a that regulates inflammatory and fibrotic activities through its receptor, receptor (CCR3). The aim of the study was to evaluate involvement CCL24-CCR3 axis in liver fibrosis inflammation assess potential blockade, by monoclonal anti-CCL24 antibody, as therapeutic strategy for non-alcoholic steatohepatitis (NASH) fibrosis.Expression CCL24 CCR3 evaluated biopsies blood samples. NAFLD/NASH pathogenesis assessed Ccl24 knockout mouse using...
Abstract Aims Acute mitral regurgitation (MR) in the setting of myocardial infarction (MI) may be result papillary muscle rupture (PMR). This condition is associated with high morbidity and mortality. We aim to evaluate feasibility transcatheter edge‐to‐edge valve repair (TEER) this acute setting. Methods results analysed data from International Registry MitraClip Mitral Regurgitation following Myocardial Infarction (IREMMI) 30 centres Europe, North America, middle east. included patients...
Gensini score (GS) provides valuable information on severity and prognosis of coronary artery disease (CAD).To evaluate the relationship between CAD determined by GS relation to ST-elevation myocardial infarction, non-ST segment elevation infarction (NSTEMI), unstable angina pectoris, chest pain (suspected syndrome admission) risk-factors for predictors severity.Observational cross-sectional study.Consecutive patients who underwent clinically-indicated angiography NSTEMI, pectoris or were...
Background Malnutrition is associated with poor prognosis in several cardiovascular diseases. However, its prognostic impact patients undergoing transcatheter edge-to-edge mitral valve repair (TEER) not well known. This study sought to assess the prevalence, clinical associations, and consequences of malnutrition TEER. Methods Results A total 892 TEER from international MIVNUT (Mitral Valve Repair Nutritional Status) registry were studied. status was assessed Controlling Status score. The...