A5007536233- Global Cancer Incidence and Screening
- Ovarian cancer diagnosis and treatment
- Colorectal Cancer Screening and Detection
- Economic and Financial Impacts of Cancer
- Endometrial and Cervical Cancer Treatments
- Cancer-related molecular mechanisms research
- Lung Cancer Treatments and Mutations
- Cancer Risks and Factors
- Colorectal Cancer Treatments and Studies
- Health Systems, Economic Evaluations, Quality of Life
- Genetic factors in colorectal cancer
- BRCA gene mutations in cancer
- Occupational and environmental lung diseases
- Reproductive System and Pregnancy
- COVID-19 and healthcare impacts
- Gastric Cancer Management and Outcomes
- IL-33, ST2, and ILC Pathways
- Gastrointestinal Tumor Research and Treatment
- Cardiovascular Health and Risk Factors
- Cancer survivorship and care
- Smoking Behavior and Cessation
- Immune cells in cancer
- Human Health and Disease
- Cytokine Signaling Pathways and Interactions
- Media Influence and Health
IQVIA (France)
2024
Centre international de recherche sur le cancer
2018-2023
University of California, Irvine
2016
National Institute for Occupational Safety and Health
2016
The Centers
2016
Roswell Park Comprehensive Cancer Center
2013
Objective Colorectal cancer (CRC) is the third most common worldwide. The geographical and temporal burden of this provides insights into risk factor prevalence progress in control strategies. We examine current future CRC 185 countries 2020 2040. Methods Data on cases deaths were extracted from GLOBOCAN database for year 2020. Age-standardised incidence mortality rates calculated by sex, country, world region Human Development Index (HDI) countries. Age-specific also estimated. predicted...
Abstract Ovarian cancer remains to have relatively poor prognosis particularly in low‐resourced settings. It is therefore important continually examine the burden of ovarian identify areas disparities. Our study aims provide an overview global using GLOBOCAN 2020 estimates by country, world region, and Human Development Index (HDI) levels, as well predicted future year 2040 HDI. Age‐standardized incidence mortality rates for 185 countries were calculated four‐tier The number new cases deaths...
BackgroundLong-term projections of cancer incidence and mortality estimate the future burden in a population, can be great use informing planning health services management resources. We aimed to rates numbers new cases deaths up until 2044 for all cancers combined 21 individual types Australia. also illustrate potential effect treatment delays due COVID-19 pandemic on colorectal rates.MethodsIn this statistical modelling study, Australia from 2020 were projected based data 2017 2019,...
Objectives As part of the International Cancer Benchmarking Partnership (ICBP) SURVMARK-2 project, we provide most recent estimates colon and rectal cancer survival in seven high-income countries by age stage at diagnosis. Methods Data from 386 870 patients diagnosed during 2010–2014 19 registries (Australia, Canada, Denmark, Ireland, New Zealand, Norway UK) were analysed. 1-year 5-year net estimated diagnosis, country, Results (One1-year) varied between (77.1% 87.5%) 59.1% 70.9% (84.8%...
In May 2018, the World Health Organization (WHO) called for elimination of cervical cancer. To monitor this initiative, we examined cancer incidence and mortality in Latin America Caribbean (LAC) region using GLOBOCAN Cancer Incidence Five Continents Series, WHO Mortality Database. We estimated number cases age-standardized rates (ASRs) 2018. also presented ASRs recorded from period 2008 to 2012. calculated annual analyzed trends all ages combined following age groups: 0-29, 30-49, 50-64...
Ovarian cancer is the eighth most common in women worldwide and incidence rates vary markedly by world region. Our study provides a comprehensive overview of ovarian trends globally, examining influence birth cohort period diagnosis on changing risk. We presented current patterns until 2012 using data from successive volumes Cancer Incidence Five Contents. The highest northern eastern European countries America. Declining were observed with exception few central Asian countries. Marked...
Disparities in breast cancer biology are evident between American women of African ancestry (AA) and European (EA) may be due, part, to differences immune function. To assess the potential role constitutional host immunity on carcinogenesis, we tested associations risk 47 single nucleotide polymorphisms (SNPs) 26 cytokine-related genes adaptive system using 650 EA (n = 335 cases) 864 AA 458 from Women's Circle Health Study (WCHS). With additional participant accrual WCHS, promising SNPs...
<h3>Introduction</h3> The International Cancer Benchmarking Partnership demonstrated international differences in ovarian cancer survival, particularly for women aged 65–74 with advanced disease. These findings suggest treatment could be contributing to survival disparities. <h3>Objective</h3> To compare clinical practice guidelines and patterns of care across seven high-income countries. <h3>Methods</h3> A comparison was performed validated by a working group. explore practice, survey...
We provide a comprehensive view of the impact alcohol consumption, tobacco smoking, excess body weight, and human papillomavirus (HPV) infection on cancer mortality years life lost (YLLs) in Brazil, Russia, India, China, South Africa, United Kingdom (UK), States (US). collected population attributable fractions four risk factors from global population-based studies applied these to estimates deaths 2020 obtain potentially preventable their 95% confidence intervals (CIs). Using tables, we...
Alongside the SARS-CoV-2 (COVID-19) pandemic, Brazil also faces an ongoing rise in cancer burden. In 2020, there were approximately 592 000 new cases and 260 deaths. Considering heterogeneities across Brazil, this study aimed to estimate impact of COVID-19 pandemic on cancer-related hospital admissions at a national regional level.The national, regional, state-specific monthly average admission rates per 100 inhabitants 95% confidence intervals (95% CIs) calculated from March July (2019:...
African American (AA) women are more likely than European (EA) to be diagnosed with early, aggressive breast cancer. Possible differences in innate immune pathways (e.g., inflammatory responses) have received little attention as potential mechanisms underlying this disparity. We evaluated distributions of selected genetic variants AA and EA women, examined their associations cancer risk within the Women's Circle Health Study (WCHS). In stage I study (864 650 women) we found that genotype...
Cancer stage at diagnosis is important information for management and treatment of individual patients as well in epidemiological studies to evaluate effectiveness health care system managing cancer patients. Population-based examine international disparities on survival by stage, however, has been challenging due the lack standardization recording variation completeness across regions countries. The International Benchmarking Partnership (ICBP) previously assessed availability comparability...
Abstract The aim of the study is to provide a comprehensive assessment incidence and survival trends epithelial ovarian cancer (EOC) by histological subtype across seven high income countries (Australia, Canada, Denmark, Ireland, New Zealand, Norway United Kingdom). Data on invasive EOC diagnosed in women aged 15 99 years during 1995 2014 were obtained from 20 registries. Age standardized rates average annual percentage change calculated for all ages age groups (15‐64 65‐99 years). Net (NS)...
Recently, ovarian cancer research has evolved considerably because of the emerging recognition that rather than a single disease, carcinomas comprise several different histotypes vary by etiologic origin, risk factors, molecular profiles, therapeutic approaches and clinical outcome. Despite significant progress in our understanding heterogeneity cancer, as well important advances, it remains eighth most frequently diagnosed women worldwide fatal gynecologic cancer. The International Agency...
Brigatinib, an ALK tyrosine kinase inhibitor (TKI), showed superior clinical efficacy in 1L for ALK+ NSCLC compared to crizotinib the phase III ALTA-1L trial. There is a lack of data on real-world treatment patterns and outcomes post-1L brigatinib. This non-interventional, multicenter, retrospective chart review study included patients with previously enrolled brigatinib arm ALTA-1L. Patients who discontinued (index event) were followed from last dose Time discontinuation (TTD),...
Background and Purpose Evidence about the efficacy of healthy pregnancy home visitation programs is needed in California’s underserved Hispanic population, where preterm birth rates are higher than nonHispanic Whites. This study describes outcome data a sample families participating MOMS Orange County program. Methods: A descriptive comparative design was used. Birth for 1,102 women who participated had live 2010 were compared with from county (N = 38, 237) state California 509, 979) same...