A5024396891- Nutrition, Genetics, and Disease
- Genetics and Physical Performance
- Cancer Risks and Factors
- Cancer-related molecular mechanisms research
- Nutritional Studies and Diet
- Epigenetics and DNA Methylation
- MicroRNA in disease regulation
- Estrogen and related hormone effects
- Aquaculture disease management and microbiota
- Prostate Cancer Treatment and Research
- Pancreatic and Hepatic Oncology Research
- Inflammatory mediators and NSAID effects
- Folate and B Vitamins Research
- Geology and Paleoclimatology Research
- Reproductive biology and impacts on aquatic species
- Cancer-related Molecular Pathways
- Geological and Geochemical Analysis
- Childhood Cancer Survivors' Quality of Life
- Prostate Cancer Diagnosis and Treatment
- RNA modifications and cancer
- Circular RNAs in diseases
- Glutathione Transferases and Polymorphisms
- RNA Research and Splicing
- Thyroid Cancer Diagnosis and Treatment
- Radiation Dose and Imaging
Chinese Academy of Fishery Sciences
2021-2025
Ocean University of China
2022-2025
Roswell Park Comprehensive Cancer Center
2014-2023
Prince of Wales Hospital
2023
Chinese University of Hong Kong
2023
Qingdao National Laboratory for Marine Science and Technology
2022
Ministry of Agriculture and Rural Affairs
2021
University at Buffalo, State University of New York
2012-2019
Fujian Agriculture and Forestry University
2017-2019
Shandong Agricultural University
2011-2015
Abstract Studies on the relationship between obesity and prostate cancer incidence are inconsistent. In part, this inconsistency may be due to a differential effect of low-grade high-grade or confounding association with risk by diabetes. We investigated associations diabetes risk. Data were from 10,258 participants (1,936 cancers) in Prostate Cancer Prevention Trial who all had presence absence determined biopsy. Multiple logistic regression was used model total cancer, polytomous cancer....
Abstract BACKGROUND Current research is inconclusive regarding the effect of obesity on outcomes after a prostate cancer diagnosis. The objective this study was to examine associations between and risks developing metastasis or cancer‐specific mortality in population‐based cohort men with cancer. METHODS Seven hundred fifty‐two middle‐aged who were enrolled case‐control remain under long‐term follow‐up for disease progression formed cohort. Body mass index (BMI) year before diagnosis...
Patient vital status generally is passively obtained by cancer registries, and no previous population-based studies have used extensive active follow-up to compute a more accurate overall survival rate for pancreatic cancer. Therefore, the authors multiple passive methods determine date of death 1,954 patients diagnosed from 1995 1999 in large study San Francisco Bay Area, California. Survival rates were estimated using Kaplan-Meier methods. Hazard ratios 95% confidence intervals...
Disparities in breast cancer biology are evident between American women of African ancestry (AA) and European (EA) may be due, part, to differences immune function. To assess the potential role constitutional host immunity on carcinogenesis, we tested associations risk 47 single nucleotide polymorphisms (SNPs) 26 cytokine-related genes adaptive system using 650 EA (n = 335 cases) 864 AA 458 from Women's Circle Health Study (WCHS). With additional participant accrual WCHS, promising SNPs...
Pancreatic cancer is highly lethal, and identifying modifiable risk factors could have substantial public health impact. In this population-based case-control study (532 cases, 1701 controls), we used principal component analysis multivariable unconditional logistic regression models to examine whether a particular dietary pattern was associated with of pancreatic cancer, adjusting for other known factors. A prudent pattern, characterized by greater intake vegetables, fruit, fish, poultry,...
Obesity has been shown to be inversely associated with breast cancer risk in premenopausal women, while increasing postmenopausal women. However, the current evidence is largely based on studies Caucasian populations. Associations women of African ancestry (AA), who have a higher prevalence obesity, evaluated few and results suggest different effects. We impact body size, fat distribution, composition among AA (978 cases 958 controls) participating Women's Circle Health Study, multi-site...
Abstract BACKGROUND: Current research is inconclusive regarding the relation between alcohol consumption and prostate cancer risk. In this study, authors examined associations of total alcohol, type alcoholic beverage, drinking pattern with risk total, low‐grade, high‐grade cancer. METHODS: Data for study came from 2129 participants in Prostate Cancer Prevention Trial (PCPT) who had detected during 7‐year trial 8791 men were determined by biopsy to be free at end. Poisson regression was used...
There are no well-established modifiable risk factors for pancreatic cancer except smoking. Some dietary have been associated with and require further study. We examined the associations among intake of specific fatty acids antioxidants in a large population-based case-control study San Francisco Bay Area. Unconditional logistic regression models were used to compute odds ratios (ORs) 95% confidence intervals (CI) as estimates relative risk. Positive observed high levels 8 individual...
Recent studies of children and adolescents who were exposed to radioactive iodine-131 (I-131) after the 1986 Chernobyl nuclear accident in Ukraine exhibited a significant dose-related increase risk thyroid cancer, but association radiation doses with tumor histologic morphologic features is not clear.A cohort 11,664 individuals Belarus aged ≤18 years at time underwent 3 cycles screening during 1997 2008. I-131 estimated from individual activity measurements taken within 2 months dosimetric...
Limiting energy-dense foods, fast and sugary drinks that promote weight gain is a cancer prevention recommendation, but no studies have evaluated intake in relation to breast risk African American (AA) women. In case-control study with 1692 AA women (803 cases 889 controls) 1456 European (EA) (755 701 controls), odds ratios (OR) 95% confidence intervals (CI) for were computed, stratifying menopausal estrogen receptor (ER) status. Among postmenopausal EA women, was associated frequent...
African American (AA) women are more likely than European (EA) to be diagnosed with breast cancer at younger ages and develop poor prognosis tumors. However, these racial differences largely unexplained. Folate other methyl‐group nutrients may related carcinogenesis, but few studies have examined associations in AA populations. We the of dietary intake risk overall, by menopausal estrogen receptor (ER) status among 1,582 (749 cases) 1,434 EA (744 using data from a case–control study, Women's...
Findings from studies of metformin use with risk cancer incidence and outcome provide mixed results; few examined associations by recency diabetes diagnosis or duration medication use. Thus, in the Women's Health Initiative, we these further explored whether differ Cox regression models were used to estimate hazard ratios (HR) their 95% confidence intervals. Diabetes was associated higher total invasive (HR, 1.13; p < 0.001) several site-specific cancers 1.2-1.4, up over twofold). also death...
Breast cancer is a heterogeneous disease, characterized by molecularly and phenotypically distinct tumor subtypes, linked to disparate clinical outcomes. American women of African ancestry (AA) are more likely than those European (EA) be diagnosed with aggressive, estrogen receptor negative (ER-) or triple breast cancer, die this disease. However, the underlying causes AA predisposition ER-/triple still largely unknown. In study, we performed high-throughput whole-genome miRNA expression...
The aim of this study was to evaluate a complex association among intake dietary vitamin D, calcium, and retinol, pancreatic cancer risk.Pancreatic cases (n = 532) diagnosed in 1995-1999 were identified using rapid case ascertainment methods frequency matched population-based controls 1,701) the San Francisco Bay Area. Detailed data collected during in-person interviews validated semi-quantitative food-frequency questionnaire. Adjusted unconditional logistic regression used estimate odds...
White tea (WT) is one of six types originally derived from Fujian Province, China. known for its health-promoting properties. However, the neuroprotective and anti-aggregatory properties WT against hallmark toxic Alzheimer’s protein, Aβ have not been investigated. In this study, WT, green (GT), oolong (OT) black (BT) were manufactured using leaves cultivar Camellia sinensis (Jin Guanyin). The protective effects these extracts then studied under oxidative stress conditions via t-bhp H2O2...