A5086676933- Radiation Dose and Imaging
- Effects of Radiation Exposure
- Radioactivity and Radon Measurements
- Radiation Therapy and Dosimetry
- Carcinogens and Genotoxicity Assessment
- Radioactive contamination and transfer
- Air Quality and Health Impacts
- Global Cancer Incidence and Screening
- Acute Lymphoblastic Leukemia research
- Thyroid Cancer Diagnosis and Treatment
- Genetic factors in colorectal cancer
- DNA Repair Mechanisms
- Cancer Risks and Factors
- Cancer Genomics and Diagnostics
- Advanced Radiotherapy Techniques
- Skin Protection and Aging
- Mathematical Biology Tumor Growth
- Medical Imaging Techniques and Applications
- Cardiac Imaging and Diagnostics
- BRCA gene mutations in cancer
- Cutaneous Melanoma Detection and Management
- Spaceflight effects on biology
- Advanced X-ray and CT Imaging
- Health Systems, Economic Evaluations, Quality of Life
- Childhood Cancer Survivors' Quality of Life
National Cancer Institute
2016-2025
Oxford Brookes University
2023-2025
National Cancer Institute
2019-2025
Division of Cancer Epidemiology and Genetics
2014-2024
Harvard University
2024
National Institutes of Health
2014-2024
United States Department of Health and Human Services
2011-2024
San Diego State University
2021-2023
University of Minnesota
2015-2023
McMaster University
2023
Although CT scans are very useful clinically, potential cancer risks exist from associated ionising radiation, in particular for children who more radiosensitive than adults. We aimed to assess the excess risk of leukaemia and brain tumours after a cohort young adults.In our retrospective study, we included patients without previous diagnoses were first examined with National Health Service (NHS) centres England, Wales, or Scotland (Great Britain) between 1985 2002, when they younger 22...
<b>Objective</b> To investigate the risk of incident myocardial infarction, congestive heart failure, and all cause mortality associated with prescription oral antidiabetes drugs. <b>Design</b> Retrospective cohort study. <b>Setting</b> UK general practice research database, 1990-2005. <b>Participants</b> 91 521 people diabetes. <b>Main outcome measures</b> Incident mortality. Person time intervals for drug treatment were categorised by class, excluding non-drug insulin. <b>Results</b> 3588...
“The accomplishments of this Programme inspire all us in public health to dream big dreams. It shows we can reach ‘impossible’ goals and lighten the burden millions world's poorest people ….” These were concluding words by former World Health Organization Director-General Gro Harlem Brundtland at closure ceremony Onchocerciasis Control West Africa (OCP) December 2002 [1]. The success OCP is so undeniable exemplary, with 600,000 cases blindness prevented, 18 million children born areas freed...
Thyroid cancer incidence rates in the United States and globally have increased steadily over last 40 years, primarily due to a tripling of papillary thyroid carcinoma (PTC). The purpose this study was analyze trends demographic, clinical, pathologic, molecular characteristics PTC from 1974 2009. We identified histologically reviewed 469 consecutive cases one US institution 4 preselected periods (1974 1985, 1990 1992, 2000, 2009) assessed BRAF RAS point mutations RET/PTC rearrangements among...
In their previous analysis of papillary thyroid carcinomas (PTCs) from an Ukrainian-American cohort that was exposed to iodine-131 ((131) I) the Chernobyl accident, authors identified RET/PTC rearrangements and other driver mutations in 60% tumors.In this study, remaining mutation-negative tumors were analyzed using RNA sequencing (RNA-Seq) reverse transcriptase-polymerase chain reaction identify novel chromosomal characterize relation with radiation dose.The ETS variant gene 6...
We previously reported evidence of a dose–response relationship between ionising-radiation exposure from paediatric computed tomography (CT) scans and the risk leukaemia brain tumours in large UK cohort. Underlying unreported conditions could have introduced bias into these findings. collected reviewed additional clinical information radiology systems (RIS) databases, underlying cause death pathology reports. conducted sensitivity analyses excluding participants with cancer-predisposing or...
Purpose CNS tumors are the most common second primary neoplasm (SPN) observed after childhood cancer in Britain, but relationship of risk to doses previous radiotherapy and chemotherapy is uncertain. Methods The British Childhood Cancer Survivor Study a national, population-based, cohort study 17,980 individuals surviving at least 5 years diagnosis cancer. Linkage population-based registries identified 247 SPNs CNS. Cohort nested case-control studies were undertaken. Results There 137...
The purpose of this study was to examine risks cancer incidence and mortality among U.S. radiation technologists performing or assisting with fluoroscopically guided interventional procedures.
<b>Objective</b> In view of mobile phone exposure being classified as a possible human carcinogen by the International Agency for Research on Cancer (IARC), we determined compatibility two recent reports glioma risk (forming basis IARC's classification) with observed incidence trends in United States. <b>Design</b> Comparison rates projected 1997-2008. We estimated combining relative risks reported 2010 Interphone study and 2011 Swedish Hardell colleagues adjusted age, registry, sex; data...
Risks of most types leukemia from exposure to acute high doses ionizing radiation are well known, but risks associated with protracted exposures, as associations between and chronic lymphocytic (CLL), not clear.