- Global Cancer Incidence and Screening
- Economic and Financial Impacts of Cancer
- Glutathione Transferases and Polymorphisms
- Health Systems, Economic Evaluations, Quality of Life
- Cancer Risks and Factors
- Colorectal Cancer Screening and Detection
- Lymphoma Diagnosis and Treatment
- Viral-associated cancers and disorders
- Multiple and Secondary Primary Cancers
- BRCA gene mutations in cancer
- Cervical Cancer and HPV Research
- Endometrial and Cervical Cancer Treatments
- Esophageal Cancer Research and Treatment
- Gastric Cancer Management and Outcomes
- Acute Lymphoblastic Leukemia research
- Testicular diseases and treatments
- Lung Cancer Treatments and Mutations
- Genetic factors in colorectal cancer
- Breast Cancer Treatment Studies
- Sarcoma Diagnosis and Treatment
- Prostate Cancer Diagnosis and Treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Colorectal and Anal Carcinomas
- Chronic Lymphocytic Leukemia Research
- Acute Myeloid Leukemia Research
National Cancer Institute
2013-2023
Division of Cancer Epidemiology and Genetics
2012-2023
National Institutes of Health
2010-2022
Emory University
2014
National Cancer Institute
1987-2012
American Cancer Society
2012
Uniformed Services University of the Health Sciences
2005-2011
Cancer Institute (WIA)
1995-2011
University of Oslo
2011
Cancer Registry of Norway
2011
Incidence rates for esophageal adenocarcinoma previously were reported to be increasing rapidly, especially among white males. Rates gastric cardia also observed rising, although less rapidly. In this article, the authors update incidence trends through 1994 and further consider by age group.Surveillance, Epidemiology, End Results (SEER) program data used calculate age-adjusted carcinoma histologic type anatomic subsite.Among males, of esophagus rose > 350% since mid-1970s, surpassing...
Thyroid cancer incidence has increased substantially in the United States over last 4 decades, driven largely by increases papillary thyroid cancer. It is unclear whether increasing of been related to mortality trends.To compare trends and tumor characteristics at diagnosis.Trends incidence-based rates were evaluated using data from Surveillance, Epidemiology, End Results-9 (SEER-9) registry program, annual percent change was calculated log-linear regression.Tumor characteristics.Annual...
Prostate cancer is the most commonly diagnosed in western men, and incidence rising rapidly countries, including low-risk populations. Age-adjusted mortality rates from 15 13 countries between 1973-77 1988-92, respectively, were compared to provide leads for future analytic studies. Large increases both of prostate seen all countries. For incidence, more pronounced United States, Canada, Australia, France Asian while medium-risk moderate. Increases ranged 25%-114%, 24%-55% 15%-104% high-,...
Abstract Thyroid cancer incidence has been rising in the United States, and this trend often attributed to heightened medical surveillance use of improved diagnostics. varies by sex race/ethnicity, these factors also influence access utilization healthcare. We therefore examined thyroid rates demographic tumor characteristics based on 48,403 patients diagnosed during 1980–2005 from Surveillance, Epidemiology End Results program National Cancer Institute. The varied histologic type, sex,...
Abstract Lung cancer rates have peaked among men in many areas of the world, but women continue to rise. Most lung cancers are squamous cell carcinoma, small or adenocarcinoma; trends vary according type. We compiled population‐based morphology‐specific incidence data from registries contributing International Agency for Research on Cancer (IARC) databases. Unspecified and carcinomas were reallocated based a registry, time period, sex age group‐specific basis. Where available, several within...
Rapid increases in the incidence of adenocarcinoma esophagus have been reported among white men. We further explored temporal patterns this disease individuals by sex, stage, and age use data from Surveillance, Epidemiology, End Results program. identified 22,759 patients January 1, 1975, through December 31, 2004, with esophageal cancer, whom 9526 were diagnosed esophagus. Among men, cancer largely attributed to a 463% increase over time period, 1.01 per 100,000 person-years (95% confidence...
Background: Inflammatory breast carcinoma (IBC) appears to be a clinicopathologic entity distinct from noninflammatory locally advanced cancer (LABC). We examined incidence and survival trends for IBC in Surveillance, Epidemiology, End Results (SEER) Program data with case definition designed capture many of its unique clinical pathologic characteristics. Methods: analyzed cases diagnosed the SEER 9 Registries ( n = 180 224), between 1988 2000. Breast were categorized using SEER's "Extent...
Abstract Soft tissue sarcomas (STS) are a heterogeneous group of uncommon tumors that show broad range differentiation may reflect etiologic distinction. Routine tabulations STS not morphology‐specific. Further, the lack inclusion arising in all organs most standard evaluations underestimates true rates. We analyzed 1978–2001 Surveillance, Epidemiology and End Results program incidence rates regardless primary site, except bones joints, using 2002 criteria WHO classification. There were...
Background Worldwide, breast cancer is the most common and leading cause of death among women. Methods To describe global trends, we compared age-adjusted incidence mortality rates over three decades (from 1973–77 to 1993–97) across several continents. Results Both varied 4-fold by geographic location between countries with highest lowest rates. Recent (1993–1997) ranged from 27/100 000 in Asian 97/100 US white Overall, North American northern European had cancer; intermediate levels were...
Lung cancer is the most common cause of death in United States, and its incidence has been rising for at least 50 years. Shifts histologic type differences sex race distribution have accompanied increased lung malignancies.Population-based data regarding reported to National Cancer Institute's Surveillance, Epidemiology, End Results (SEER) program 15-year period 1973-1987 were analyzed.Results indicate that from 1973-1977 1983-1987, age-adjusted rates by 30%, with gain markedly greater women...
Background: Clinical investigations have shown prognostic heterogeneity within the non-Hodgkin's lymphomas (NHLs) according to histology, but few descriptive studies considered NHLs by subgroup. Our purpose is assess demographic patterns and any notable increases in population-based rates of different histologic subgroups NHL. Methods: Using data collected Surveillance, Epidemiology, End Results Program National Cancer Institute, we calculated incidence for major clinicopathologic categories...
Abstract Background: Previous research has noted higher cancer mortality rates and lower survival among males than females. However, systematic comparisons of these two metrics by sex have been limited. Methods: We extracted U.S. vital data from the Surveillance, Epidemiology End Results Database for 36 cancers age period 1977 to 2006. compared sex-specific examined male-to-female rate ratios (MRR). also case which included date diagnosis, sex, primary site, tumor stage grade, time, status,...
It is not yet clear whether increasing melanoma incidence real or recent trends mainly reflect improved diagnosis. To address this question, we examined the most patterns among white population stratified by sex, age, tumor stage, and thickness use of data from Surveillance, Epidemiology, End Results Program.We log-transformed age-specific rates for 5-year age groups time periods year diagnosis birth cohort. Melanoma were further broader (<40 years, 40-59 > =60 years) stage thickness. Rates...
Background: The increasing incidence of thyroid cancer in the United States is well documented. In this study, we assessed patterns by histologic type according to demographic and tumor characteristics further our understanding these cancers. Methods: We used National Cancer Institute's Surveillance, Epidemiology, End Results (SEER) program for cases diagnosed during 1992–2006 investigate four major types gender, race/ethnicity, age as registry, stage, size. Results: Among women, papillary...
Abstract BACKGROUND Although cervical carcinoma incidence and mortality rates have declined in the U.S. greatly since introduction of Papanicolaou smear, this decline has not been uniform for all histologic subtypes. Therefore, authors assessed differential squamous cell (SCC) adenocarcinoma (AC) cervix by race disease stage past 25 years. METHODS Data from nine population‐based cancer registries participating Surveillance, Epidemiology, End Results (SEER) Program were used to compute...
Cancer incidence rates have been reported to be increasing in the United States, although trends vary according form of cancer.We identify cancers accounting for rising incidence, quantify changes that occurred from mid-1970s early 1990s, and contrast mortality provide clues determinants temporal patterns.Sex-, race-, age-specific age-adjusted 5-year periods 1987-1991 versus 1975-1979 were calculated 28 among men 30 women using data Surveillance, Epidemiology, End Results (SEER) Program...
Public concern about possible increases in childhood cancer incidence the United States led us to examine recent and mortality patterns.Cancers diagnosed 14540 children under age 15 years from 1975 through 1995 reported nine population-based registries National Cancer Institute's Surveillance, Epidemiology, End Results Program were investigated. Age-adjusted was analyzed according anatomic site histologic categories of International Classification Childhood Cancer. U.S. rates calculated....
Abstract Background: Cancer epidemiology articles often point out that cancer rates tend to be higher among males than females yet rarely is this theme the subject of investigation. Methods: We used Surveillance, Epidemiology and End Results program data compute age-adjusted (2000 U.S. standard population) sex-specific incidence male-to-female rate ratios (IRR) for specific sites histologies period 1975 2004. Results: The 10 cancers with largest IRR were Kaposi sarcoma (28.73), lip (7.16),...
Objectives: Rapid increases in the incidence of esophageal adenocarcinoma (EAC) high-income countries past decades have raised public health concerns. This study is first to predict future burden cancer by histological subtype using international data. Methods: Data on year diagnosis, sex, histology, and age group were extracted from 42 registries 12 included last three volumes (VIII–X) Cancer Incidence Five Continents, contributing at least 15 years consecutive Numbers new cases rates...