Fernando Javier Aguilar-Ayala

ORCID: 0000-0002-9114-1807
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About
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Research Areas
  • dental development and anomalies
  • Dental Health and Care Utilization
  • Mesenchymal stem cell research
  • Epigenetics and DNA Methylation
  • Bee Products Chemical Analysis
  • Aging, Health, and Disability
  • Bone and Dental Protein Studies
  • Oral microbiology and periodontitis research
  • Oral and Maxillofacial Pathology
  • Bone Tissue Engineering Materials
  • Histone Deacetylase Inhibitors Research
  • Cleft Lip and Palate Research
  • Antimicrobial agents and applications
  • Cancer-related gene regulation
  • Dental Erosion and Treatment
  • Periodontal Regeneration and Treatments
  • Electrospun Nanofibers in Biomedical Applications
  • Medical and Biological Ozone Research
  • Endodontics and Root Canal Treatments
  • Tissue Engineering and Regenerative Medicine
  • Polymer Surface Interaction Studies
  • Silk-based biomaterials and applications
  • 3D Printing in Biomedical Research
  • Craniofacial Disorders and Treatments
  • Surgical Sutures and Adhesives

Autonomous University of Yucatán
2014-2024

Objective . We quantified the prevalence of impacted maxillary canines (IMC) and their association with other dental anomalies (DAs). Materials Methods A retrospective study was done 860 patients 12 to 39 years age. The IMC calculated compared by sex. sample divided into a control group an impaction group, in both for series anomalies: agenesis, supernumerary teeth, shape upper laterals (microdontia, peg barrel shape, talon cusp), fusion, gemination, transposition, amelogenesis imperfecta....

10.1155/2017/7326061 article EN cc-by International Journal of Dentistry 2017-01-01

Objective. To identify dental pain prevalence and associated factors in Mexican schoolchildren. Methods. This cross-sectional study included 1,404 schoolchildren aged 6 to 12 years from public schools the city of Pachuca de Soto, Hidalgo, Mexico. Data were collected through a questionnaire that addressed sociodemographic socioeconomic factors, eating hygiene habits, behavior variables. The dependent variable was self-reported months prior survey. analyzed using nonparametric statistics...

10.1155/2017/7431301 article EN cc-by BioMed Research International 2017-01-01

Chitosan is a natural polymer that can sustain not only osteoblast adhesion and proliferation for bone regeneration purposes, but it also claimed to exhibit antibacterial properties towards several Gram-positive Gram-negative bacteria. In this study, chitosan was modified with sodium hyaluronate, crosslinked polyethylene glycol diglycidyl ether (PEGDE) both cytotoxicity behavior studied. The presence of hyaluronate PEGDE on detected by FTIR, XRD, XPS. (CHT) films showed better thermal...

10.3390/app11031267 article EN cc-by Applied Sciences 2021-01-30

It has been reported that chitosan scaffolds, due to their physicochemical properties, stimulate cell proliferation in different tissues of the human body. This study aimed determine physicochemical, mechanical, and biological properties scaffolds crosslinked with ammonium hydroxide, pH values, better understand behavior depending on biomaterial. Scaffolds were either neutralized sodium hydroxide solution, washed distilled water until reaching a neutral pH, or kept at alkaline pH....

10.3390/ijms232314822 article EN International Journal of Molecular Sciences 2022-11-26

Dental tissue-derived mesenchymal stem cells (DT-MSCs) are a promising resource for tissue regeneration due to their multilineage potential. Despite accumulating data regarding the biology and differentiation potential of DT-MSCs, few studies have investigated adipogenic capacity. In this study, we features dental pulp (DPSCs), as well in vitro effects different media on these cells, compared them those periodontal ligament (PLSCs) follicle (DFSCs). DFSC, PLSCs, DPSCs exhibit similar...

10.3390/jpm11080738 article EN Journal of Personalized Medicine 2021-07-28

Introduction Propolis has been used traditionally for different human diseases and even recently as dental biomaterials because of its antibacterial, antimycotic, anti-inflammatory properties. However, a proper correlation between in vitro vivo properties not clearly established. Methods The composition propolis was determined by high-performance liquid chromatography–ultraviolet mass spectrometry (HPLC-UV-MS). Viability ethanolic solution evaluated thiazolyl blue tetrazolium bromide (MTT)...

10.1177/2058739220935280 article EN cc-by-nc European Journal of Inflammation 2020-01-01

Obesity is a significant health concern that has reached alarming proportions worldwide. The overconsumption of high-energy foods may cause metabolic dysfunction and promote the generation new adipocytes by contributing to several obesity-related diseases. Such concerns demand deeper understanding origin if we want develop therapeutic approaches. Recent findings indicate adipocyte development facilitated tight epigenetic reprogramming, which required activate gene program change fate...

10.3389/fcell.2022.791667 article EN cc-by Frontiers in Cell and Developmental Biology 2022-02-24

To determine any associations between obesity and caries activity in the mixed dentition stage among primary school children a low-income Mexican school.

10.3290/j.ohpd.a43366 article EN Oral health & preventive dentistry 2020-02-14

Background: We assessed the effect of propolis on antibacterial, mechanical, and adhesive properties a commercial poly(alkenoate) cement. Methods: The cement was modified with various concentrations propolis, antibacterial assays were performed against S. mutans by both MTT agar diffusion tests. compressive, flexural, also evaluated. Results: showed activity in assays, although reductions compressive (from 211.21 to 59.3 MPa) flexural strength 11.1 6.2 noted addition while (shear bond novel...

10.3390/polym15071676 article EN Polymers 2023-03-28

Dental pulp (DP) represents an accessible and valuable source promising of stem cells for clinical application. However, there are some disadvantages associated with the isolation dental (DPSCs), which include size weight tissue needed to yield sufficient culturing in vitro. Therefore, objective this study was compare vitro histomorphometry DP from permanent (premolars, third molar), supernumerary deciduous teeth patients between 5 25 years old regards weight, length, width cell density four...

10.7717/peerj.8212 article EN cc-by PeerJ 2019-12-06

Antecedentes: la caries de infancia temprana es una enfermedad bacteriana que se presenta en niños menores 71 meses edad, con prevalencia puede llegar hasta 90% poblaciones altamente vulnerables. Objetivo: determinar y los factores riesgo pacientes 48 meses, así como relación existente entre las caries. Materiales métodos: estudio descriptivo transversal el incluyeron 63 sin distinción género, desde 9 edad (edad promedio 26.8 meses). Se utilizó un cuestio- nario registraron para efectuó...

10.18233/apm35no4pp259-266. article ES cc-by Acta Pediátrica de México 2014-08-06

Biomaterials and stem cells are essential components in the field of regenerative medicine. Various biomaterials have been designed that appropriate biochemical biophysical characteristics to mimic microenvironment an extracellular matrix. Dental (DT-MSCs) represent a novel source for development autologous therapies due their easy availability. Although research on DT-MSCs has progressed, there still challenges molecular mechanisms involved regulating behavior DT-MSCs. In this review,...

10.3390/app12125815 article EN cc-by Applied Sciences 2022-06-08

This study's objective was to compare the total and outside cleft prevalence of dental anomalies (DA) between patients with lip palate (CLP) a control group. retrospective cross-sectional study done under case-control design. The case group consisted 192 non-syndromic complete CLP, while included 411 patients. All subjects had orthopantomography, intra, extraoral photographs. agenesis, supernumerary teeth, impacted transposition, microdontia were compared using chi-squared test (P < .05)....

10.1097/md.0000000000029383 article EN cc-by-nc Medicine 2022-08-05

Dental stem cells (DSCs) are multipotent with high proliferation capacity and multilineage differentiation. Few studies have compared the cellular characteristics adipogenic differentiation potential of DSCs derived from tissues same individual. The objective this work was to evaluate differences in growth characteristics, expression mesenchymal (MSCs)-specific markers,&#x0D; proteomic profile response differentiation, dental pulp periodontal ligament obtained a single donor. were isolated...

10.15517/ijds.2024.58892 article EN Odovtos - International Journal of Dental Sciences 2024-02-22

The present study aimed to determine the genetic variants of PAX9, MSX1, and AXIN2 in Mayan probands with non-syndromic dental agenesis (NSDA) from Yucatan, Mexico. We sequenced DNA specific exons genes by using Sanger method seven familial NSDA attending orthodontic clinics Merida, bioinformatically analyzed four genomes unaffected people ancestry for comparative purposes. Two had oligodontia (14 or 16 missing teeth) five hypodontia (1-2 teeth). found following variants: rs8670 MSX1;...

10.15517/ijds.2024.60223 article EN Odovtos - International Journal of Dental Sciences 2024-05-30

Non-formation of a tooth impacts the morphology alveolar bone, which may, in turn, generate an imbalance facial growth. This retrospective case-control study aimed to determine whether observable differences exist growth patients with dental agenesis relative complete dentition controls.The sample comprised 75 agenesis, and each case was paired two controls same age gender (n = 150). All were measured cephalometrically (31 variables), both groups compared student's t- or Z-test (P < 0.05)....

10.1016/j.jds.2020.03.006 article EN cc-by-nc-nd Journal of Dental Sciences 2020-04-01

ANTECEDENTES: los niños con Síndrome de Down (SD) generalmente tienen características morfogenéticas que predisponen a patologías bucales; por lo tanto, el análisis las la saliva constituye una herramienta diagnóstica su estado salud bucal.OBJETIVOS: a) Comparar valores promedio pH salival y tasa flujo (TFS), según género edad. b) tipos TFS, c) Determinar si existe correlación entre TFS.MATERIALES Y MÉTODOS: en 100 pacientes SD (M = 50, F 50) 0 18 años edad pertenecientes instituciones...

10.18233/apm38no6pp355-3621502 article ES cc-by Acta Pediátrica de México 2017-11-13
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