A5026458533- Plant Reproductive Biology
- Plant Molecular Biology Research
- Polysaccharides and Plant Cell Walls
- Plant pathogens and resistance mechanisms
- Cancer Research and Treatments
- Ubiquitin and proteasome pathways
- Biosensors and Analytical Detection
- Cancer Genomics and Diagnostics
- Plant biochemistry and biosynthesis
- Biocrusts and Microbial Ecology
- Plant Stress Responses and Tolerance
- Plant nutrient uptake and metabolism
- Plant-Microbe Interactions and Immunity
- Plant Physiology and Cultivation Studies
- Advanced biosensing and bioanalysis techniques
- Cancer Cells and Metastasis
- SARS-CoV-2 detection and testing
Jilin University
2025
First Hospital of Jilin University
2025
Shenyang Agricultural University
2020-2024
Solid tissue biopsy is fundamental in guiding surgeons during intraoperative and peri-operative management of cancer patients. However, conventional histopathologic methods depend heavily on the expertise trained pathologists, facing challenges accuracy efficiency. Methods: Here, we show that unbiased labeling proteins within sections using tumor-selective dyes enhances tumor-specific signals, enabling robust accurate differentiation tumors from normal tissues less than 45 min. This...
Actin binding proteins and transcription factors are essential in regulating plant root hair growth response to various environmental stresses; however, the interaction between these two remains poorly understood. Apical subapical thick actin bundles necessary for terminating rapid elongation of cells. Here, we show that Arabidopsis (
Actin cytoskeleton is essential for root hair formation. However, the underlying molecular mechanisms of actin dynamics in formation response to abiotic stress are largely undiscovered. Here, genetic analysis showed that actin-depolymerizing protein ADF7 and actin-bundling VILLIN1 (VLN1) were positively negatively involved Arabidopsis respectively. Moreover, RT-qPCR, GUS staining, western blotting, revealed played an important role inhibiting expression function VLN1 during Filament...
Actin filaments are essential for plant adaptation to high temperatures. However, the molecular mechanisms of actin in thermal remain unclear. Here, we found that expression Arabidopsis depolymerization factor 1 (AtADF1) was repressed by Compared with wild-type seedlings (WT), mutation AtADF1 and overexpression led promoted inhibited growth under temperature conditions, respectively. Further, temperatures induced stability plants. WT, Atadf1-1 mutant showed more normal while opposite...
Detecting foodborne pathogens on-site is crucial for ensuring food safety, necessitating the development of rapid, cost-effective, highly sensitive, and portable devices. This paper presents an integrated microfluidic biosensing system designed rapid sensitive detection Salmonella typhimurium (S. typhimurium). The comprises a chip with versatile valve, recombinase polymerase amplification (RPA) nucleic acid detection, customized real-time fluorescence system. valve combines functions active...
Abstract Root hairs (RHs), extensive structures of root epidermal cells, are important for plant nutrient acquisition, soil anchorage, and environmental interactions. Excessive production the phytohormone ethylene (ET) leads to substantial hair growth, manifested as tolerance deficiencies. However, molecular basis ET during growth in response starvation remains unknown. Herein, we found that a critical transcription factor, GLABRA 2 (GL2), inhibits Arabidopsis (Arabidopsis thaliana). GL2...
Actin depolymerizing factors (ADFs), as the important actin-binding proteins (ABPs) with depolymerizing/severing actin filaments, play a critical role in plant growth and development, response to biotic abiotic stresses. However, information function of ADF family melon remains unclear. In this study, 9 genes (CmADFs) were identified, distributed 4 subfamilies, located on 6 chromosomes respectively. Promoter analysis revealed that CmADFs contained large number cis-acting elements related...
Actin dynamics are essential for root hair development, however, the underlying molecular mechanisms of actin binding protein cooperation and plant abiotic stress responses largely unknown. Here, genetic analysis displayed that depolymerizing ADF7 bundling VLN1 positively negatively involved in development Arabidopsis, respectively. Moreover, acts upstream by RT-qPCR, Gus staining, Western blot genetics. The observation F-actin shows inhibits VLN1, leading to decline filament (F-actin) thick...