A5103006493- Prion Diseases and Protein Misfolding
- RNA regulation and disease
- Connexins and lens biology
- Brucella: diagnosis, epidemiology, treatment
- Health and Wellbeing Research
- Natural product bioactivities and synthesis
- Education, Safety, and Science Studies
- Helicobacter pylori-related gastroenterology studies
- Flavonoids in Medical Research
- Body Composition Measurement Techniques
- Metastasis and carcinoma case studies
- Gastrointestinal Tumor Research and Treatment
- Animal Genetics and Reproduction
- Phytochemistry and Biological Activities
- Trace Elements in Health
- Seaweed-derived Bioactive Compounds
- Immune Response and Inflammation
- Biochemical Acid Research Studies
- Diverse Approaches in Healthcare and Education Studies
- Education and Learning Interventions
- Diagnosis and treatment of tuberculosis
- Quinazolinone synthesis and applications
- Signaling Pathways in Disease
- Synthesis and Biological Evaluation
- Alcoholism and Thiamine Deficiency
Hallym University
2014-2020
Hallym Polytechnic University
2015
Chosun University
2009-2011
Scrapie infection, which converts cellular prion protein (PrPC) into the pathological and infectious isoform (PrPSc), leads to neuronal cell death, glial activation PrPSc accumulation. Previous studies reported that PrPC regulates RhoA/Rho-associated kinase (ROCK) signaling connexin 43 (Cx43) expression is upregulated in vitro vivo prion-infected models. However, whether there a link between RhoA/ROCK Cx43 disease pathogenesis uncertain. Here, we investigated role of diseases using infection...
Prion infection leads to neuronal cell death, glial activation, and the accumulation of misfolded prion proteins. However, altered cellular environments in animals with diseases are poorly understood. In central nervous system, cells connect cytoplasm adjacent via connexin (Cx)-assembled gap junction channels allow direct exchange small molecules, including ions, neurotransmitters, signaling which regulate activities connected cells. Here, we investigate role Cx43 pathogenesis diseases....
Scrapie is a mammalian transmissible spongiform encephalopathy or prion disease that predominantly affects sheep and goats. has been shown to overcome the species barrier via experimental infection of other rodents. To confirm re-transmissibility mouse-adapted ME7 scrapie strain ovine protein (PrP) transgenic mice, mice an ovinized mouse line carrying Suffolk PrP gene contained A136 R154 Q171/ARQ allele were intracerebrally inoculated with brain homogenates obtained from terminally ill...
본 연구에서는 고등학교 배구선수를 대상으로 성별에 따른 등속성 근기능, 무산소성 운동능력 및 기초체력을 비교 하였다. 연구대상자는 여자 10명과 남자 12명이었으며, 이들을 무릎관절 운동능력, 근력, 근지구력, 순발력, 민첩성, 유연성 등을 평가하였다. 차이를 검증하기 독립표본 t-test를 실시하였다. 근력 결과, 왼쪽 신근력(p < .001)과 오른쪽 .001), 굴근력(p 굴근력 (p .001) 모두 여자선수가 남자선수 보다 낮은 것으로 나타났고, 굴/신 비율도 나타났다(p .05). 무산소성파워 최대파워(p 평균파워(p 전체에너지(p .01) 나타났다. 기초체력 남자선수는 여자선수 서전트 점프(p 배근력(p 윗몸일으키기(p .05)가 높은 나타났으나, 여자선수는 반복점프(p .01), 사이드스텝(p 눈감고 외발서기(p .05), 체전굴(p .01)과 체후굴(p .05)에서 나타났 다. 결론적으로, 연구는 배구선수들은 하지 기초체력에 차이가 있음 을 제안하였다.