A5023427299- Inflammatory Bowel Disease
- Microscopic Colitis
- Gut microbiota and health
- Diverticular Disease and Complications
- Probiotics and Fermented Foods
- Anorectal Disease Treatments and Outcomes
- Clostridium difficile and Clostridium perfringens research
- Mobile Health and mHealth Applications
- Gastrointestinal motility and disorders
- Misinformation and Its Impacts
- Digestive system and related health
- Celiac Disease Research and Management
- Public Relations and Crisis Communication
- Digital Mental Health Interventions
- Social Media and Politics
- Antifungal resistance and susceptibility
- Impact of Technology on Adolescents
- Genetic factors in colorectal cancer
- Pelvic floor disorders treatments
- Mobile Learning in Education
- Social Media in Health Education
Tufts Medical Center
2022-2024
Tufts University
2023
University Medical Center
2023
Abstract Background Although gut fungi have been implicated in the immunopathogenesis of inflammatory bowel disease, fungal microbiome has not deeply explored across endohistologic activity and treatment exposure ulcerative colitis. Methods We analyzed data from SPARC IBD (Study a Prospective Adult Research Cohort with Inflammatory Bowel Disease) registry. evaluated composition fecal samples 98 patients colitis endoscopic (n = 43), 41), biologic 82). Across all subgroups, we assessed...
Abstract Reduced butyrate-production capacity has been reported in fecal microbial communities patients with active ulcerative colitis. However, the of mucosal microbiome from vs quiescent mucosa colitis unexplored. We sought to determine diversity and relative abundance bacterial fungal endoscopically UC, aimed predict contributions butyrate synthesis. Systematic, segmental right- left-sided biopsies were obtained (n = 13) or 17) colonic mucosa, among 15 pan-colonic Dietary fiber intake was...
While there is increasing interest in microbiome-directed therapies for patients with ulcerative colitis (UC), the identification of microbial targets remains elusive, underlining need novel approaches.
With the recent surges of new COVID-19 variants, clear public health messaging on social media has become more vital than ever. One important source information are messages and reactions expressed by medical professionals. However, content promogulated these experts not fully understood. In this study, we demonstrate how unique Twitter data can be used to explore doctors' early months pandemic. We examine 265,412 English-language tweets about from doctors a comparable subset non-doctors...
Abstract INTRODUCTION The incidence of obesity in patients with inflammatory bowel disease (IBD) is increasing and there limited data on the effects phenotype. Several studies have investigated association perianal fistulizing conflicting results. In this study, we aim to examine relationship between prevalence severity complications Crohn’s (CD). METHODS We conducted a cross-sectional study CD treated at tertiary care center from 2012 2022. Collected included sex, race, smoking history,...
Abstract Background Background: Candida in the gut has been recently linked to inflammatory activity UC. However, relationship between abundance and bacterial microbiome remains poorly understood, how these relationships evolve over disease course UC is unknown. Methods Methods: We utilized data from Study of a Prospective Adult Research Cohort with IBD (SPARC-IBD) Plexus examine taxonomic composition fungal mycobiome cross-sectionally longitudinally time. Differential was assessed using...
<sec> <title>BACKGROUND</title> The increasing use of secure messaging in medical centers has led to concerns about alert fatigue and the impact on clinician burnout. This study is aimed at characterizing patterns between nurses medicine interns inform interventions mitigate these issues. </sec> <title>OBJECTIVE</title> aim analyze an academic center using TigerConnect platform, with goal informing reduce improve well-being. <title>METHODS</title> observational analyzed transactions 25...
OBJECTIVES/GOALS: Although gut fungi have been implicated in the immunopathogenesis of inflammatory bowel disease, fungal microbiome has not deeply explored across endo-histologic activity and treatment-exposure ulcerative colitis. METHODS/STUDY POPULATION: Our retrospective cohort was derived from Study a Prospective Adult Research Cohort with Inflammatory Bowel Disease. We evaluated composition fecal samples 98 colitis patients endoscopic (n=43), (n=41), biologic-exposure (n=98). Across...
Introduction: The extraintestinal manifestations (EIM) of inflammatory bowel disease (IBD) have been seen at higher rates in patients with obesity. Adipose tissue has demonstrated to promote proinflammatory states. Metabolic syndrome, a clinical condition central obesity, dyslipidemia, hypertension, and impaired glucose metabolism, share features immune dysregulation IBD. We suspect that the systemic state metabolic syndrome would lead more EIM syndrome. Methods: Clinical data was extracted...
Patients with classic symptoms of celiac disease are often initially tested for serum tissue transglutaminase-immunoglobulin A (tTG-IgA) and total immunoglobulin (IgA) levels concurrently, as IgA deficiency can lead to falsely low tTG-IgA. There no guidelines incidental findings elevated when testing disease. In our study, we described the proportion patients suspicion who had factors that may be associated these findings. We studied management identify its clinical significance. To...
Introduction: Previous studies have shown that obesity in inflammatory bowel disease (IBD) is associated with an increased risk of morbidity. We aimed to examine the effect on presentation and complications. Methods: conducted a retrospective chart review all IBD patients treated at our tertiary care center between 1996 2022. Data collected included demographics, clinical characteristics current medications. defined underweight as body mass index (BMI) < 18.5, normal weight 18.5-24.9,...
Introduction: Gut microbial disruption has been implicated in the pathogenesis of ulcerative colitis (UC). There is increasing evidence that fungal microbiome (mycobiome) may drive inflammation mouse models UC, and can prognosticate clinical response to fecal transplantation among patients with UC. However, it remains unclear if composition altered during active compared quiescent disease Methods: We analyzed sequencing data from Study a Prospective Adult Research Cohort Inflammatory Bowel...