A5070393918- Healthcare Policy and Management
- Genetic Mapping and Diversity in Plants and Animals
- Genetic Associations and Epidemiology
- Pharmaceutical industry and healthcare
- Nutrition, Genetics, and Disease
- Pharmaceutical Economics and Policy
- Folate and B Vitamins Research
- COVID-19 epidemiological studies
- Consumer Market Behavior and Pricing
- Insurance and Financial Risk Management
- Education Systems and Policy
- COVID-19 Pandemic Impacts
- Health, Environment, Cognitive Aging
- Patient Satisfaction in Healthcare
- Healthcare cost, quality, practices
- Cognitive Abilities and Testing
- Global Health Care Issues
- Employment and Welfare Studies
- Bacterial Infections and Vaccines
- Atherosclerosis and Cardiovascular Diseases
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Genetics and Neurodevelopmental Disorders
- Misinformation and Its Impacts
- Medication Adherence and Compliance
- Intellectual Property and Patents
Harvard University
2018-2024
Harvard University Press
2020-2022
National Bureau of Economic Research
2022
Dana-Farber/Harvard Cancer Center
2022
Yale University
2016
Pingry School
2010
SUNY Downstate Health Sciences University
1984
State University of New York
1984
Abstract Humans vary substantially in their willingness to take risks. In a combined sample of over one million individuals, we conducted genome-wide association studies (GWAS) general risk tolerance, adventurousness, and risky behaviors the driving, drinking, smoking, sexual domains. We identified 611 approximately independent genetic loci associated with at least our phenotypes, including 124 tolerance. report evidence substantial shared influences across tolerance behaviors: 72 contain...
Price transparency regulations aim to help patients make informed decisions about medical care, but enforcing these rules is a policy challenge. There may be an association between financial penalties and hospital compliance for price regulations.
To compare the PROMIS Physical Function and Pain Interference Computer Adaptive Tests (PROMIS PF CAT PI CAT) with time to brake (TTB) in patients complex lower extremity traumas for evaluating whether can safely return driving.Prospective.Level-1 trauma center.Sixty-three injuries pelvis, acetabulum, hip, femur, knee, tibia/fibula, ankle, foot within 15 weeks of treatment.The TTB were tested at various points postoperatively on a computerized driving simulator. Patients concurrently...
This cross-sectional study examines associations between characteristics of US hospitals and their compliance with Centers for Medicare & Medicaid Services regulations transparency insurance-negotiated prices.
We use high-frequency Google search data, combined with data on the announcement dates of non-pharmaceutical interventions (NPIs) during COVID-19 pandemic in U.S. states, to isolate direct impact state-level NPIs own-state unemployment an event study framework. Exploiting differential timing introduction restaurant and bar limitations, non-essential business closures, stay-at-home orders, large-gatherings bans, school emergency declarations, we analyze how searches for claiming insurance...
Recent subsidy enhancements in Affordable Care Act (ACA) Marketplaces made many low-income enrolles (below 150% of the federal poverty level [FPL]) eligible for 2 free silver-tier plans. However, an unintended consequence this structure is that identity which silver plans are will often "turn over" between years, requiring enrollees actively initiate premium payment (or lose coverage). The prevalence free-plan turnover not known.
Drug copayment coupons to reduce patient cost-sharing have become nearly ubiquitous for high-priced brand-name prescription drugs. Medicare bans such on the grounds that they are kickbacks induce utilization, but commonly used by commercially-insured enrollees. We estimate causal effects of branded drugs without bioequivalent generics using variation in coupon introductions over time and comparing differential responses across enrollees commercial Advantage plans. Using data net-of-rebate...
Abstract Objective To test the effectiveness of physician incentives for increasing patient medication adherence in three drug classes: diabetes medication, antihypertensives, and statins. Data Sources Pharmacy medical claims from a large Medicare Advantage Prescription Drug Plan January 2011 to December 2012. Study Design We conducted randomized experiment (911 primary care practices 8,935 nonadherent patients) effect paying physicians measured patients’ 18 (6) months before (after)...
With the recent surges of new COVID-19 variants, clear public health messaging on social media has become more vital than ever. One important source information are messages and reactions expressed by medical professionals. However, content promogulated these experts not fully understood. In this study, we demonstrate how unique Twitter data can be used to explore doctors' early months pandemic. We examine 265,412 English-language tweets about from doctors a comparable subset non-doctors...
We estimate the causal effects of drug copayment coupons, which reduce consumer cost sharing for branded prescription drugs, on net-of-rebate price and quantities sold. show that coupon introductions increase quantity drugs without generic substitutes sold by 23–25 percent commercial segment relative to Medicare Advantage, where coupons are banned. To quantify resulting equilibrium effects, we a discrete choice model demand multiple sclerosis simulate negotiations. prices 8 higher due being...
Abstract Background Antimicrobial stewardship programs (ASPs) require significant effort and resources. While a large literature has linked ASP policies to lower antibiotic utilization costs, ASPs’ effect on resistance is less well understood. Most prior studies have relied before-vs-after comparisons in single institution which may be confounded by time trends resistance. We use difference-in-differences research design investigate the impact of hospital-specific policy changes...
The US incentivizes drug innovation via patents as well market exclusivity periods awarded by the Food and Drug Administration. We estimate causal effects of extending for an important class: antibiotics. Using a difference-in-differences approach, we show that Generating Antibiotic Incentives Now (GAIN) Act – policy change granted 5 additional years antibiotics but not antivirals or vaccines led to significant increase in phase 3 clinical trials. also find evidence GAIN generated novel...
The 2010 Pingry School S.M.A.R.T. Team (Students Modeling A Research Topic) has been working with the Banta laboratory at Columbia University to design and produce accurate, three‐dimensional physical models of alcohol dehydrogenase AdhD other enzymes applications for use in a biofuel cell. Features being engineered into these include (1) self‐assembly hydrogels, (2) alternate cofactor use, (3) broader substrate specificity. Discussions allowed students RP‐RasMol studied lab highlight their...