A5008830437- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Luminescence and Fluorescent Materials
- Organic Light-Emitting Diodes Research
- Magnetism in coordination complexes
- Porphyrin and Phthalocyanine Chemistry
- Supramolecular Chemistry and Complexes
- Advanced biosensing and bioanalysis techniques
- Metal complexes synthesis and properties
- Crystallography and molecular interactions
- Lanthanide and Transition Metal Complexes
- Liquid Crystal Research Advancements
- Molecular Sensors and Ion Detection
- Advanced Nanomaterials in Catalysis
- bioluminescence and chemiluminescence research
- RNA modifications and cancer
- Molecular spectroscopy and chirality
- Nanoplatforms for cancer theranostics
- Electrochemical sensors and biosensors
- Photochemistry and Electron Transfer Studies
- Synthesis and properties of polymers
- Analytical Chemistry and Sensors
- RNA Interference and Gene Delivery
- Photodynamic Therapy Research Studies
- Organoselenium and organotellurium chemistry
University of Münster
2020-2024
CeNTech
2020-2024
Fundación Ciencias Exactas y Naturales
2016-2020
University of Buenos Aires
2016-2020
University of Duisburg-Essen
2020
Consejo Nacional de Investigaciones Científicas y Técnicas
2020
In this work, we describe the synthesis, structural and photophysical characterization of four novel Pd(ii) Pt(ii) complexes bearing tetradentate luminophoric ligands with high photoluminescence quantum yields (Φ L) long excited state lifetimes (τ) at room temperature, where results were interpreted by means DFT calculations. Incorporation fluorine atoms into ligand favors aggregation thereby, a shortened average distance between metal centers, which provides accessibility to...
Abstract The small arginine-rich protein protamine condenses complete genomic DNA into the sperm head. Here, we applied its high RNA binding capacity for spontaneous electrostatic assembly of therapeutic nanoparticles decorated with tumour-cell-specific antibodies efficiently targeting siRNA. Fluorescence microscopy and DLS measurements these nanocarriers revealed formation a vesicular architecture that requires presence antibody-protamine, defined excess free SMCC-protamine, anionic siRNA...
Abstract Singlet dioxygen has been widely applied in different disciplines such as medicine (photodynamic therapy or blood sterilization), remediation (wastewater treatment) industrial processes (fine chemicals synthesis). Particularly, it can be conveniently generated by energy transfer between a photosensitizer's triplet state and upon irradiation with visible light. Among the best photosensitizers, substituted zinc(II) phthalocyanines are prominent due to their excellent photophysical...
Abstract Background Acute myeloid leukemia (AML) is a fatal clonal hematopoietic malignancy, which results from the accumulation of several genetic aberrations in progenitor cells, with worldwide 5-year survival prognosis about 30%. Therefore, development more effective therapeutics novel mode action urgently demanded. One common mutated gene AML DNA-methyltransferase DNMT3A whose function and maintenance still unclear. To specifically target “undruggable” oncogenes, we initially invented an...
Abstract Two series with three Pt(II) complexes each ( PtL Ph ‐n , Fpy ) bearing asymmetric tetradentate ligands as dianionic luminophores variable alkyl chain lengths were synthesized. Hence, ligand is distinguished by one of its cyclometallating rings (phenyl vs. 2,6‐difluoropyrid‐3‐yl). Steady‐state and time‐resolved photoluminescence spectroscopic studies in diluted solutions at room temperature glassy matrices 77 K show that the emissive state mainly centered on invariantly...
The lanthanide binding ability of a macrocyclic ligand H6L2 comprising two bis(iminomethyl)phenol and calix[4]arene units has been studied. is ditopic which provides dinuclear neutral complexes composition [Ln2(L2)(MeOH)2] (Ln = La (1), Eu (2), Tb (3), Yb (4)) in very good yield. X-ray crystal structure analyses for 2 3 show that (L2)6- accommodates seven coordinated ions distorted monocapped trigonal prismatic/octahedral coordination environment. UV-vis spectroscopic titrations performed...
Bistable rotaxanes were used to develop pH-switchable systems for singlet dioxygen photoproduction. Based on the combination of a Zn(II)-tetraphenylporphyrin photosensitizer, which was attached macrocycle, and black-hole-quencher, as one rotaxane-stoppers, oxygen production could be switched on/off ((Δ= 0.15/0.03) by addition base/acid. However, we found that only sufficiently long linker between both stations thread enabled switchability, direction switching inversed with regard original...
Rotaxanes are mechanically interlocked molecules where a ring (macrocycle) is threaded onto linear molecule (thread). The position of the macrocycle on different stations thread can be controlled in response to external stimuli, making rotaxanes applicable as molecular switches. Here we show that bistable based combination Zn(II) tetraphenylporphyrin photosensitizer, attached macrocycle, and black-hole-quencher, thread, capable singlet oxygen production which switched on/off by addition...
Abstract We describe the role of chalcogen variation (O, S, Se and Te) on photoluminescence properties ether‐based luminophores showing aggregation‐induced fluorescence phosphorescence. To this end, a library eleven different compounds with varying substitution patterns was synthesized analyzed in terms their photophysical properties. Ortho ‐ tetra selenoethers revealed remarkable phosphorescence best our knowledge, these are one first phosphorescent organic selenium‐containing featuring AIE...
Abstract Two isoleptic complexes involving Pd(II) and Pt(II) centres with a tetradentate luminophoric ligand were adsorbed onto Laponite ( LAP ), yielding H 2 O-dispersible nanohybrids remarkable photoexcited state properties. The adsorption promoted rigidification of the coordination compounds suppression roto-vibrational deactivation pathways, thus enhancing performance molecular species. Interestingly, room temperature phosphorescence was achieved in case Pd(II)-containing nanohybrid...
A series of Pd(II) (PdLOMe, PdLOHex) and Pt(II) (PtLOMe, PtLOHex) complexes bearing tetradentate ligands as dianionic luminophores were synthesized. Hence, the cyclometallating chelators alternatively decorated with two n-hexyloxy (LOHex) or methoxy (LOMe) moieties to promote crystallization processability. The new compounds unambiguously characterized by means multiple NMR spectroscopies mass spectrometry well single crystal X-ray diffractometric analysis (PtLOMe PdLOMe). Steady state...
A series of emissive liquid crystalline materials based on salicylidene derivatives is reported and investigated with respect to their thermoresponsive mechanochromic properties. Single-crystal analysis temperature-dependent powder X-ray diffraction measurements allowed us correlate the intermolecular organization mesogens changes in fluorescence behavior. As a proof-of-principle study, we employed dynamics imine bond transamination reactions for postsynthetic tuning behavior as further step...
Abstract A series of main chain discotic liquid crystal polymers, synthesized following a new approach based on the incorporation triphenylene units in both comonomers, show ordered columnar mesophases very wide thermal range, including room temperature. The introduction branching points same kind increases their range and gives rise to glassy low‐temperature phases. Room temperature extrusion these polymers yields fibers with molecules oriented perpendicular mechanical stress, an...
The crystalline structures of four homologues the 1,2-dibromo-4,5-dialkoxybenzene series [Br2C6H2(OCnH2n + 1)2 for n = 2, 12, 14 and 18] have been solved by means single-crystal crystallography. Comparison along series, including previously reported 10 16 derivatives, shows a clear metric trend (b c essentially fixed growing linearly with n), in spite some subtle differences space groups and/or packing modes. A uniform pattern aliphatic chains has found 12 to 18 homologues, which slightly...
A series of four regioisomeric Pt(II) complexes (PtLa-n and PtLb-n) bearing tetradentate luminophores as dianionic ligands were synthesized. Hence, both classes cyclometallating chelators decorated with three n-hexyl (n = 6) or n-dodecyl 12) chains. The new compounds unambiguously characterized by means multiple NMR spectroscopies mass spectrometry. Steady-state time-resolved photoluminescence spectroscopy well quantum chemical calculations show that the effect regioisomerism on emission...
The synthesis, structure, magnetic, and photophysical properties of two dinuclear, luminescent, mixed-ligand [Cr
Abstract The front cover artwork is provided by the group of Jun.‐Prof. Dr. Jens Voskuhl [Universität Duisburg‐Essen (UDE), Germany]. image shows deep‐sea frog fishes known to attract their prey using a light emitting organ. Here we adapted illustration adding corresponding chalcogen as lantern, shining in emission colour described contribution. Read full text Article at 10.1002/cptc.202000002 .