A5059585512- Effects and risks of endocrine disrupting chemicals
- Reproductive biology and impacts on aquatic species
- Pharmaceutical and Antibiotic Environmental Impacts
- Trace Elements in Health
- Heavy Metal Exposure and Toxicity
- Mercury impact and mitigation studies
- Estrogen and related hormone effects
- Environmental Toxicology and Ecotoxicology
- Heavy metals in environment
- Insect and Pesticide Research
- Genetics, Aging, and Longevity in Model Organisms
- Aquaculture Nutrition and Growth
- Heme Oxygenase-1 and Carbon Monoxide
- Drug Transport and Resistance Mechanisms
- Toxic Organic Pollutants Impact
- Microplastics and Plastic Pollution
- Analytical chemistry methods development
- Pharmacogenetics and Drug Metabolism
- Mining and Resource Management
- Pesticide Residue Analysis and Safety
- Recycling and Waste Management Techniques
- Chemistry and Chemical Engineering
- Pesticide and Herbicide Environmental Studies
- Agriculture Sustainability and Environmental Impact
- Plant and animal studies
Prefectural University of Kumamoto
2016-2025
Kumamoto University
2020-2025
National Institute of Technology, Ariake College
2014
Kyoto Prefectural University
2010
University of Miyazaki
2008
Ehime University
2005
Japan Science and Technology Agency
2002-2004
Shibuya (Japan)
2002
Nagasaki University
1987-1998
University of South Dakota
1988-1993
In their safety evaluations of bisphenol A (BPA), the U.S. Food and Drug Administration (FDA) a counterpart in Europe, European Safety Authority (EFSA), have given special prominence to two industry-funded studies that adhered standards defined by Good Laboratory Practices (GLP). These same agencies much less weight risk assessments large number independently replicated non-GLP conducted with government funding leading experts various fields science from around world.
The present study demonstrates the occurrence of pharmaceuticals and personal care products (PPCPs) in surface water from Mankyung River, South Korea. Samples collected at 5 Sites along theMankyung River were assayed using a liquid chromatograph coupled with tandem mass spectrometer (LC/MS/MS) for 13 PPCPs. Overall, 11 out selected PPCPs, which span range therapeutic classes one product, detected samples River. most prevalent contaminants ibuprofen, average concentrations ranging not (ND) to...
Artisanal and small-scale gold mining (ASGM) poses a significant global threat due to mercury emissions resulting health hazards. This study focuses on assessing these risks in the Abu Hamad ASGM community Sudan. Utilizing Mercury Analyzer 3000 (NIC), analyses of twelve soil samples (including one tailings sample) seven water revealed highest concentrations near amalgam burning locations: 34.8 mg/kg (S06) 3.26 µg/L (W03). Concentrations decrease with distance, exceeding (S05 = 19.0 mg/kg)....
Mercury contamination stemming from artisanal and small-scale gold mining (ASGM) operations poses significant environmental health concerns. This study focuses on the Darmali area in River Nile State, Sudan, where reprocessing of amalgamation tailings has led to mercury contamination. assessed content soil samples, as well tap groundwater, evaluate human risks ASGM activities assess levels within area. Soil water samples were collected various locations, including agricultural, residential,...
Bladder cancer is the most common urologic malignancy in USA. Tobacco smoking generates oxidative DNA damage and induces bladder cancer. Base excision repair (BER) a very important mechanism for repairing damage. There are many enzymes involved BER. Human oxoguanine glycosylase 1 (hOGG1) X-ray cross-complementing (XRCC1) enzyme genes of Actually, hOGG1 codon 326 polymorphism was associated with risk lung oesophagus stomach On other hand, among several XRCC1 gene polymorphisms, 399 reported...
Tea is one of the world's most popular beverages due to health promoting effects. Despite these, there have been concerns about adverse effects tea contamination by neonicotinoid insecticides. Only a handful studies on insecticides in carried out and this study was therefore performed determine concentrations seven 20 metabolites Japanese green leaves, black leaves from Sri Lanka; assess Maximum Daily Intake (MDI) From results, parent compounds were detected beverages. Dinotefuran (3004...
The indispensability of biometals nickel, copper, and selenium in pharmaceutical, agricultural, other industrial applications, coupled with their release from mining processes, has made them potent environmental contaminants, especially when present aquatic ecosystems at levels above the essential range. toxicity these fish embryogenesis, including levels, was studied using medaka embryos. Test solutions (0.001–10 ppm) biometals, along an isotonic solution as a control, were introduced into...
We investigated the effects of nonylphenol (NP) and triclosan (TCS) on production vitellogenin (Vg), testosterone (T), hepatic cytochrome P450 1A 2B activities in male South African clawed frogs (Xenopus laevis). In a 14-d waterborne exposure test, no significant differences level plasma Vg synthesis were observed among control, 10, 50, 100 μg/l NP 20, 100, 200 TCS treatment groups. Intraperitoneal injection with 2, μg/g body weight resulted levels control all However, groups...
BackgroundMicrocystin-LR, a cyclic heptapeptide, possesses the ability to inhibit serine/threonine protein phosphatases PP1 and PP2A and, consequently, exhibits acute hepatocytotoxicity. Moreover, microcystin-LR induces cellular proliferation, resulting in tumor-promoting activity hepatocytes. However, mechanisms that regulate balance between cell death proliferation after treatment remain unclear.ObjectiveWe examined contribution of transcription factor p53, as well hepatic uptake...
Nine different food cans, packed with water, were heat-treated for 30 min at 80 or 100°C in order to elucidate the trends associated leaching of bisphenol A (BPA) from internal coatings. Low levels BPA detected water all unheated rising 0.06 32 ng/cm2 after heating 100°C. Reducing heat-treatment temperature 80°C was found reduce concentration contained by up two-thirds. The cans that recorded highest concentrations have components (lid, bottom body) high available contents.