A5030845854- Characterization and Applications of Magnetic Nanoparticles
- Nanoparticle-Based Drug Delivery
- Iron oxide chemistry and applications
- Magnetic Properties and Synthesis of Ferrites
- Micro and Nano Robotics
- Additive Manufacturing and 3D Printing Technologies
- Pickering emulsions and particle stabilization
- Electrospun Nanofibers in Biomedical Applications
- Nanomaterials for catalytic reactions
- Bone Tissue Engineering Materials
- Surfactants and Colloidal Systems
- Lanthanide and Transition Metal Complexes
- Electrostatics and Colloid Interactions
- Luminescence Properties of Advanced Materials
- Electrohydrodynamics and Fluid Dynamics
- Microfluidic and Bio-sensing Technologies
- Polymer Surface Interaction Studies
- Adsorption and biosorption for pollutant removal
- 3D Printing in Biomedical Research
- Nanoplatforms for cancer theranostics
- Polymer Nanocomposites and Properties
- Surgical Sutures and Adhesives
- Water Treatment and Disinfection
- Gold and Silver Nanoparticles Synthesis and Applications
- Geomagnetism and Paleomagnetism Studies
Clemson University
2015-2024
Materials Science & Engineering
2014-2023
National Institute of Standards
2019
National Institute of Standards and Technology
2019
Universidade Estadual de Campinas (UNICAMP)
2019
Parthenope University of Naples
2019
Alexandru Ioan Cuza University
2019
Honeywell (United States)
2019
Tohoku University
2019
National Institute of Research and Development for Technical Physics
2019
The use of magnetic nanoparticles in biomedical applications provides are a wealth opportunities. Nonetheless, to truly understand the interactions these materials biological media, detailed characterization is necessary with complex systems. This Feature highlights some "best practices" analytical techniques and challenges measurement properties materials.
One of the greatest challenges in cancer therapy is to develop methods deliver chemotherapy agents tumor cells while reducing systemic toxicity noncancerous cells. A promising approach localizing drug release employ drug-loaded nanoparticles with coatings that drugs only presence specific triggers found target such as pH, enzymes, or light. However, many parameters affect nanoparticle distribution and rate, it difficult quantify situ. In this work, we show proof-of-principle for a "smart"...
As a recent advancement in reaction engineering, magnetic induction heating (MIH) is utilized to initiate the intended reactions by enabling self-heating of ferromagnetic catalyst particles. While MIH can be energy-efficient and industrially scalable, its full potential has been underappreciated catalysis because perception that merely an alternative approach. Unexpectedly, we show MIH-triggered could go beyond standard thermal catalysis. Specifically, probing representative Pt/Fe3O4...
Surface active amine-functionalized silica coated magnetic iron oxide nanoparticles were prepared by a simple two-step process for adsorbing CO2 gas from aqueous medium. First, oleic acid (OA) particles (denoted as Fe3O4-OA) coprecipitation method. Then, the surface of Fe3O4-OA was with using tetraethyl orthosilicate. Finally, aminated Fe3O4/SiO2-NH2 concomitantly formed reactions 3-aminopropyl triethoxysilane silica-coated particles. The formation materials confirmed Fourier transform...
Ligand exchange of hydrophilic molecules on the surface hydrophobic iron oxide nanoparticles produced via thermal decomposition chelated precursors is a common method for producing aqueous suspensions particles biomedical applications. Despite wide use, relatively little understood about efficiency ligand and how much removed. To address this issue, we utilized radiotracer technique to track radiolabeled (14)C-oleic acid with ligands magnetite nanoparticles. Iron functionalized were modified...
Magnetic nanocapsules were synthesized for controlled drug release, magnetically assisted delivery, and MRI imaging. These magnetic nanocapsules, consisting of a stable iron nanocore mesoporous silica shell, by encapsulation ellipsoidal hematite in silica, partial etching the core acid, reduction hydrogen. The provided high saturation magnetization was against oxidation at least 6 months air 1 month aqueous solution. hollow space between shell used to load anticancer T
When X-rays irradiate radioluminescence nanoparticles, they generate visible and near infrared light that can penetrate through centimeters of tissue. X-ray luminescence tomography (XLT) maps the location these radioluminescent contrast agents at high resolution by scanning a narrow beam tissue sample collecting every position. Adding magnetic functionality to particles would enable them be guided, oriented, heated using external fields, while their spectrum could imaged with XLT...
Abstract A method is developed to fabricate monodispersed biocompatible Yb/Er or Yb/Tm doped β‐NaGdF 4 upconversion phosphors using polyelectrolytes prevent irreversible particle aggregation during conversion of the precursor, Gd 2 O(CO 3 ) •H O:Yb/Er Yb/Tm, :Yb/Er Yb/Tm. The polyelectrolyte on outer surface nanophosphors also provided an amine tag for PEGylation. This employed PEGylated magnetic with Fe O as core and a shell. These have relatively high saturation magnetization (7.0 emu g −1...
It has been recently reported that for some suspensions of magnetic nanoparticles the transverse proton relaxation rate, R2, is dependent on time sample exposed to an applied field. This dependence linked formation linear aggregates or chains in field via numerical modeling. widely known chain occurs more concentrated ferrofluids systems and this affect ferrofluid properties. In work we examine relationships between colloidal stability, these structures, changes observed rate aqueous...
Ligand exchange on the surface of hydrophobic iron oxide nanoparticles is a common method for controlling chemistry desired application. Furthermore, ligand with small-molecule ligands may be necessary to obtain particles specific size or functionality. Understanding what extent occurs and factors affect it important optimization this critical procedure. However, quantifying amount difficult because limitations commonly used characterization techniques. Therefore, we utilized radiotracer...
The colloidal stability of dispersions comprised magnetite nanoparticles coated with polydimethylsiloxane (PDMS) oligomers was investigated theoretically and experimentally. Particle−particle interaction potentials in a theta solvent good for the PDMS were predicted by calculating van der Waals, electrostatic, steric, magnetic forces as functions interparticle separation distances. A variety nanoparticle sizes size distributions considered. Calculations potential dilute suspensions indicated...
Biocompatible, hydrophobic nanoparticles show great promise as biomaterials. This paper reports the synthesis, magnetic separation, and characterization of magnetite with polydimethylsiloxane (PDMS) adsorbed onto their surfaces. The particle size distributions were narrowed by employing a separation/fractionation technique to remove larger particles aggregates from an original distribution. A probability averaging method that incorporates cores derived TEM is proposed, together...
We report on the development of a sensitive high frequency susceptometer capable measuring in range from 25 kHz up to 10 MHz with volume susceptibility sensitivity 3.5×l0−5 at 100 corresponding about 0.3% measured AC susceptibility. In combination previous reported DynoMag system dynamic magnetic properties 1 Hz 200 we are thus able measure between sensitivity. will show susceptometry applications and results within fields hyperthermia characterization nanoparticle different particle sizes...
A novel tri-nitroDOPA terminated polymer based ligand has been developed for the stabilization of magnetite nanoparticles. The synthesis involves a process in which ethylene oxide is polymerized using trivinyl initiator, modified with carboxylic acid free radical addition mercaptoundecanoic acid, and then functionalized nitroDOPA N,N′-dicyclohexylcarbodiimide (DCC) N-hydroxysuccinimide (NHS) chemistry. This newly synthesized compared to more traditional monofunctional catechol ligands...
Multifunctional nanoparticles are synthesized for both pH‐triggered drug release and imaging with radioluminescence, upconversion luminescent, magnetic resonance (MRI). The particles have a yolk‐in‐shell morphology, radioluminescent core, an upconverting shell, hollow region between the core shell loading drugs. They by controlled encapsulation of nanophosphor yolk in silica partial etching acid, luminescent shell. Metroxantrone, chemotherapy drug, was loaded into space X‐ray phosphor...
Magnetite (Fe3O4) nanoparticles have been synthesized and complexed with carboxylate-functional block copolymers, then aqueous dispersions of the complexes were investigated as functions their chemical morphological structures. The copolymer dispersants had either poly(ethylene oxide), oxide-co-propylene or oxide-b-propylene oxide) outer blocks, all them a polyurethane center that contained pendent carboxylate groups. formed through interactions carboxylates surfaces magnetite nanoparticles....