A5089790368- Bacteriophages and microbial interactions
- CRISPR and Genetic Engineering
- Evolution and Genetic Dynamics
- RNA and protein synthesis mechanisms
- Bacterial Genetics and Biotechnology
- Identification and Quantification in Food
- Cytomegalovirus and herpesvirus research
- Vibrio bacteria research studies
- Genetic diversity and population structure
- Genomics and Phylogenetic Studies
Weizmann Institute of Science
2020-2025
It has become clear in recent years that anti-phage defense systems cluster non-randomly within bacterial genomes so-called "defense islands". Despite serving as a valuable tool for the discovery of novel systems, nature and distribution islands themselves remain poorly understood. In this study, we comprehensively mapped system repertoire >1,300 strains Escherichia coli, most widely studied organism phage-bacteria interactions. We found are usually carried on mobile genetic elements...
Resource5 June 2020Open Access Highly active rubiscos discovered by systematic interrogation of natural sequence diversity Dan Davidi Department Plant and Environmental Sciences, Weizmann Institute Science, Rehovot, Israel Search for more papers this author Melina Shamshoum Zhijun Guo School Biological Nanyang Technological University, Singapore, Singapore Yinon M Bar-On Noam Prywes Molecular Cell Biology, University California, Berkeley, CA, USA Aia Oz Migal Galilee Research Institute,...
Abstract Bacterial anti-phage defense systems are frequently clustered in microbial genomes, forming islands. This genomic property enabled the recent discovery of multiple based on their co-localization with known systems, but full arsenal mechanisms bacteria is still unknown. In this study we report 21 new that protect from phages, computational analyses and phage infection experiments. We find protein domains to be involved eukaryotic anti-viral immunity, including ISG15-like proteins,...
Abstract In recent years it has become clear that anti-phage defence systems cluster non-randomly within bacterial genomes in so-called “defence islands”. Despite serving as a valuable tool for the discovery of novel systems, nature and distribution islands themselves remain poorly understood. this study, we comprehensively mapped repertoire >1,300 strains Escherichia coli, most widely studied organism terms phage-bacteria interactions. We found preferentially integrate at several dozens...