Daniel J. Holland

ORCID: 0000-0002-9192-5396
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • NMR spectroscopy and applications
  • Granular flow and fluidized beds
  • Advanced MRI Techniques and Applications
  • Mineral Processing and Grinding
  • Fluid Dynamics and Mixing
  • Particle Dynamics in Fluid Flows
  • Cyclone Separators and Fluid Dynamics
  • Heat and Mass Transfer in Porous Media
  • Atomic and Subatomic Physics Research
  • Electrical and Bioimpedance Tomography
  • Landslides and related hazards
  • Metabolomics and Mass Spectrometry Studies
  • Cancer Diagnosis and Treatment
  • Soil and Unsaturated Flow
  • Advanced NMR Techniques and Applications
  • Sparse and Compressive Sensing Techniques
  • Advanced Electron Microscopy Techniques and Applications
  • Advanced Neuroimaging Techniques and Applications
  • Spectroscopy and Chemometric Analyses
  • Microfluidic and Capillary Electrophoresis Applications
  • Seismic Imaging and Inversion Techniques
  • Characterization and Applications of Magnetic Nanoparticles
  • Electron and X-Ray Spectroscopy Techniques
  • Plant-Derived Bioactive Compounds
  • Lattice Boltzmann Simulation Studies

University of Canterbury
2016-2025

Merck (Germany)
2024-2025

University of Technology Sydney
2020

University of Cambridge
2007-2016

Washington State University Spokane
2014

Schlumberger (United Kingdom)
2008-2011

Microsoft Research (United Kingdom)
2011

The Ohio State University
2008

Auckland City Hospital
2000

Tufts University
1951-1999

Make it snappy! The use of compressed sensing to reconstruct multidimensional NMR spectra enables significant reductions in recording time. Thus, 3D HNCA (blue) and HN(CO)CA (green) sufficient quality for rapid protein-backbone assignment were reconstructed from only 16 % the fully sampled data. generality method its robustness noise should make more broadly applicable, example, solid-state spectroscopy. Detailed facts importance specialist readers are published as ”Supporting Information”....

10.1002/anie.201100440 article EN Angewandte Chemie International Edition 2011-06-06

Recent advances in additive manufacturing technology have enabled rapid and inexpensive prototyping of designs to explore shape effects across a range engineering applications. In this work, we measure the heat transfer performance exchangers based on triply periodic minimal surfaces (TPMS). The results showed that sheet gyroid TPMS design produced high rate moderate pressure drop. was further investigated determine its over porosities ranging from 40% 85%, hydraulic diameters 2 10 mm, wall...

10.1016/j.ijheatmasstransfer.2023.124264 article EN cc-by-nc-nd International Journal of Heat and Mass Transfer 2023-05-15

In this paper, we apply electron tomography (ET) to the study of three-dimensional (3D) morphology iron oxide nanoparticles (NPs) with reactive concave surfaces. The ability determine quantitatively volume and shape NP concavity is essential for understanding key-lock mechanism responsible destabilization gold nanocrystals within concavity. We show that quantitative ET enhanced greatly by application compressed sensing (CS) techniques tomographic reconstruction. High-fidelity tomograms using...

10.1021/nl202253a article EN Nano Letters 2011-09-27

This paper investigates the spatial resolution of computational fluid dynamics–discrete element method (CFD-DEM) simulations a bubbling fluidized bed for seven different void fraction schemes. Fluid grids with cell sizes 3.5, 1.6, and 1.3 particle diameters were compared. The velocity maps from all schemes in good qualitative agreement experimental data collected using magnetic resonance imaging (MRI). Refining grid improved quantitative due to more accurate representation flow near gas...

10.1021/acs.iecr.7b04638 article EN Industrial & Engineering Chemistry Research 2018-02-12

Background M6223 is an intravenous (IV), Fc-competent, fully human, antagonistic, anti-T cell immunoreceptor with immunoglobulin and tyrosine-based inhibitory motif domains (TIGIT) antibody. Bintrafusp alfa (BA) a bifunctional fusion protein that simultaneously blocks nonredundant immunosuppressive TGF-β PD-(L)1 pathways. Methods This first-in-human, dose-escalation study in patients advanced solid tumors (N=58; aged ≥18 years, ECOG PS≤1) evaluated alone (Part 1A, n=40; 10–2400 mg every 2...

10.1136/jitc-2024-010584 article EN cc-by-nc-nd Journal for ImmunoTherapy of Cancer 2025-02-01

Ultrafast magnetic resonance imaging, employing spiral reciprocal space sampling and compressed sensing image reconstruction, is used to acquire velocity maps of the liquid phase in gas-liquid multiphase flows. Velocity were acquired at a rate 188 frames per second. The method enables quantitative characterization wake dynamics single bubbles bubble swarms. To illustrate this, we use new technique demonstrate role vorticity driving secondary motions, governing structure turbulence

10.1103/physrevlett.108.264505 article EN Physical Review Letters 2012-06-28

Electrical capacitance tomography (ECT) is well established for 2D imaging of multiphase flow. Increasingly, ECT now being used to image in 3D. In this paper we examine the challenges 3D reconstruction using simulations a 24 electrode (4 planes 6 electrodes each) sensor. particular, demonstrate that changes sensor can be as much an order magnitude less than and condition number 106. We show with dominated by contributions from most widely separated electrodes. If these pairs are eliminated...

10.1088/0957-0233/24/10/105406 article EN cc-by Measurement Science and Technology 2013-09-17

Electrical capacitance tomography (ECT) provides a means for non-invasively imaging multiphase flows, such as those in fluidised beds. Traditionally ECT images are reconstructed using the assumption that distribution of permittivity varies smoothly throughout sensor region. However, many applications there step changes permittivity, example, between bubble and particulate phases bed, smoothness is flawed. In this article Total Variation Iterative Soft Thresholding (TV-IST) algorithm used to...

10.1016/j.ces.2015.01.011 article EN cc-by Chemical Engineering Science 2015-01-14

Benchtop NMR analysis combined with model-based fitting protocols can detect commercial honey adulteration down to 5 wt%.

10.1039/d2ay01757a article EN Analytical Methods 2023-01-01

Additive manufacturing (3D printing) is enabling novel porous structures such as triply periodic minimal surfaces (TPMS) that may help improve the efficiency of various applications in chemical engineering. In this work, a range Schwarz–Diamond TPMS were examined experimentally terms printability and pressure drop. X-ray computed tomography scans used to show shape was accurately printed, however systematic reduction porosity observed compared with each designed structure. The drop through...

10.1016/j.ces.2023.119039 article EN cc-by-nc-nd Chemical Engineering Science 2023-06-24

The flexibility, affordability and ease of use benchtop 1H NMR spectroscopy makes it potentially very interesting for assessing the quality wine types monitoring fermentation process. However, low spectral resolution complexity mixtures hinder direct quantification important parameters and, thus, prevent its widespread as an analytical tool in wineries. We show here that these problems can be solved using model-based data processing. In a first step, accuracy new approach was evaluated by...

10.1016/j.foodres.2025.115741 article EN cc-by Food Research International 2025-01-23
Coming Soon ...