A5077995638- Protein purification and stability
- Microfluidic and Capillary Electrophoresis Applications
- Polymer Surface Interaction Studies
- Monoclonal and Polyclonal Antibodies Research
- Additive Manufacturing and 3D Printing Technologies
- Proteins in Food Systems
- Electrohydrodynamics and Fluid Dynamics
- Microfluidic and Bio-sensing Technologies
- 3D Printing in Biomedical Research
- Electrowetting and Microfluidic Technologies
- Granular flow and fluidized beds
- Advanced Cellulose Research Studies
- Lattice Boltzmann Simulation Studies
- Glycosylation and Glycoproteins Research
- Infant Nutrition and Health
- Innovative Microfluidic and Catalytic Techniques Innovation
- Galectins and Cancer Biology
- Legionella and Acanthamoeba research
- Viral Infectious Diseases and Gene Expression in Insects
- Biopolymer Synthesis and Applications
- Analytical Chemistry and Chromatography
- Protein Hydrolysis and Bioactive Peptides
- Heat and Mass Transfer in Porous Media
- Mineral Processing and Grinding
- Bacterial biofilms and quorum sensing
University of Canterbury
2015-2024
MacDiarmid Institute for Advanced Materials and Nanotechnology
2023
Christ University
2020
Japan External Trade Organization
2014
Universiti Malaysia Pahang Al-Sultan Abdullah
2012
Australian Nuclear Science and Technology Organisation
2010
The University of Queensland
2008-2010
Ludwig-Maximilians-Universität München
2008
University of Waikato
1996-2006
General Electric (New Zealand)
2004
Recent advances in additive manufacturing technology have enabled rapid and inexpensive prototyping of designs to explore shape effects across a range engineering applications. In this work, we measure the heat transfer performance exchangers based on triply periodic minimal surfaces (TPMS). The results showed that sheet gyroid TPMS design produced high rate moderate pressure drop. was further investigated determine its over porosities ranging from 40% 85%, hydraulic diameters 2 10 mm, wall...
Size exclusion chromatography (SEC) was used to determine the viscosity radii of equivalent spheres for proteins covalently grafted with poly(ethylene glycol) (PEG). The radius such PEGylated found depend on molecular weight native protein and total PEG but not weight, or PEG-to-protein molar grafting ratio. Results suggest PEG's form a dynamic layer over surface proteins. geometry this results in area-to-volume ratio approximately equal that randomly coiled molecule weight. Two simple...
Abstract Therapeutic proteins conjugated with branched poly(ethylene glycol) (PEG) have extended in vivo circulation half‐lives compared to linear PEG‐proteins, thought be due partly a greater hydrodynamic volume of which reduces the glomerular sieving coefficient. In this paper, viscosity radii PEGylated α‐lactalbumin ( M r = 14.2 kDa) and bovine serum albumin 67 prepared PEGs (with nominal molecular weights 5, 10, 20 40 were experimentally using size exclusion chromatography (SEC). PEG...
Amine functionalized poly(ethylene glycols) (PEGs) with molecular weights 2000 and 4000 Da were covalently grafted onto carboxy modified hydrophilic Sephadex derivatives hydrophobic polystyrene using anhydrous amine conjugation methods. Varying PEG surface concentration layer thickness achieved by controlling the reaction parameters analyzed X-ray photoelectron spectroscopy (XPS). C−O intensities obtained from high resolution C 1s scans correlated standard overlay model to study grafting...
Additive manufacturing (3D printing) is enabling novel porous structures such as triply periodic minimal surfaces (TPMS) that may help improve the efficiency of various applications in chemical engineering. In this work, a range Schwarz–Diamond TPMS were examined experimentally terms printability and pressure drop. X-ray computed tomography scans used to show shape was accurately printed, however systematic reduction porosity observed compared with each designed structure. The drop through...
Spherical polyacrylamide/magnetite (PAM) composite beads, suitable for use in a magnetically stabilized fluidized bed (MSFB), were manufactured by suspension polymerization method. Yield of beads depended on the type and concentration buffer used during as well pH. More stabilizer was needed to prevent bead agglomeration magnetite increased. Bead diameter ranged from less than 60 600 μm, depending reaction conditions, mean size distribution decreased with increasing impeller speed. The...
Cellulose-based hydrogels were prepared by dissolving cellulose in aqueous sodium hydroxide (NaOH)/urea solutions and casting it into complex shapes the use of sacrificial templates followed thermal gelation solution. Both gelling temperatures used (40⁻80 °C), as well method heating either induction form a water bath hot press or radiation microwaves could be shown to have significant effect on compressive strength modulus hydrogels. Lower shorter times found result stronger stiffer gels....
Abstract Mixed matrix membranes (MMMs), which incorporate adsorptive particles during membrane casting, can be prepared simply and have performances that are competitive with other chromatography materials. The application of MMM for fractionation β‐Lactoglobulin from bovine whey is described in this article. was using ethylene vinyl alcohol polymer lewatit anion exchange resin to form a flat sheet membrane. characterized terms structure its static dynamic binding capacities were measured....
In the last few decades we have witnessed a rapid advance in design of new biotherapeutic products using viral particles. The current limitations manufacturing these particles are often associated with their purification processes. Additive opened possibility printing 3D porous chromatographic structures to be used bio-separation field. Here, report production and use 3D-printed cellulose columns functionalized two different ligands: diethylaminoethyl (DEAE) hydroxyapatite for oncolytic...
Powder-bed binder-jetting 3D printing requires the use of a liquid binder or ink. These binders/inks have been widely tailored for individual application. This article covers proof-of-concept development an ink powder-bed printer. The formulation in our work is both catalytically active and used to bind catalyst substrate. A modified, commercially available inkjet cartridge spread onto powder surface, forming shapes layer-wise fashion produce green bodies that are heat-treated post-print....
A new, widely applicable process that combines reaction and separation in a single unit operation is described. The process, size-exclusion chromatography (SERC), simultaneously allows control of the extent reactions which molecular size altered products reactants. In SERC, moving zone formed by injection reactants onto column. Reactants are partitioned differently within mobile phase, resulting different linear flow rates through therefore removed selectively from zone, minimizing their...