C7-H-functionalized indoles are ubiquitous structural units of biological and pharmaceutical compounds for numerous antiviral agents against SARS-CoV or HIV-1. Thus, achieving site-selective functionalizations the C7-H position indoles, while discriminating among other bonds, is in high demand. Herein, we disclose activations by ruthenium(II) biscarboxylate catalysis under mild conditions. Base-assisted internal electrophilic-type substitution C-H ruthenation weak O-coordination enabled...

Although Zr-based metal-organic frameworks (MOFs) exhibit robust chemical and physical stability in the presence of moisture acidic conditions, their susceptibility to nucleophilic attacks from bases poses a critical challenge overall stability. Herein, we systematically investigate UiO-66 (UiO = University Oslo) MOFs basic solutions. The impact 11 standard bases, including inorganic salts organic on these is examined. destruction framework confirmed through powder X-ray diffraction (PXRD)...

A cobalt–rhodium heterobimetallic nanoparticle-catalyzed reductive cyclization of 2-(2-nitroaryl)acetonitriles to indoles has been achieved. The tandem reaction proceeds without any additives under the mild conditions (1 atm H2 and 25 °C). This procedure could be scaled up gram scale. catalytic system is significantly stable these reused more than ten times loss activity.

Abstract 2,2′‐Bipyridine (BPY) is a versatile organic ligand, well known for its strong metal‐chelating properties, which make it crucial component in coordination chemistry. When integrated into metal–organic frameworks (MOFs), BPY significantly enhances the material's particularly catalysis, due to ability coordinate with wide range of metal ions. This review focuses on metalation BPY‐incorporated MOFs (MOF‐BPYs), an emphasis secondary cations at sites. The metals are categorized first‐,...

Abstract Herein, we disclose osmaelectrocatalyzed C−H activations that set the stage for electrooxidative alkyne annulations by benzoic acids. The osmium electrocatalysis enables site‐ and chemoselective with unique levels of selectivity. isolation unprecedented osmium(0) osmium(II) intermediates, along crystallographic characterization analyses spectrometric spectroscopic in operando techniques delineate a synergistic redox catalyst regime. Detailed mechanistic studies revealed facile...

A selective chemosensor was developed for the colorimetric detection of CN⁻ and S²⁻ in aqueous solution.

Heterogeneous copper catalysis enabled photoinduced C-H arylations under exceedingly mild conditions at room temperature. The versatile hybrid catalyst provided step-economical access to arylated heteroarenes, terpenes and alkaloid natural products with various aryl halides. could be reused without significant loss of catalytic efficacy. Detailed studies in terms TEM, HRTEM XPS analysis the catalyst, among others, supported its outstanding stability reusability.

Transition-metal-catalyzed C–H aminations via nitrene transfer processes are powerful synthetic methods to construct valuable amines. Over the past decade, significant efforts in field have resulted an expansion utility of chemistry, enabling use these carbon–nitrogen bond-forming reactions complex organic molecule syntheses. This Perspective highlights silver-catalyzed that achieve chemo-, site-, and enantioselective transformations using simple N-dentate ligands can serve as stepping...

Surface coating with dopamine (DA) has received significant attention over the past decade due to its compatibility other surface techniques and versatility, making it applicable solid surfaces regardless of substrate shape. Much effort been made elucidate origin capability, as a result, many important factors affecting properties have determined. For example, reported that length carbon chain between catechol amino groups, attachment specific functional groups ring group, replacement group...

Abstract Polydopamine (PDA) is a synthetic material synthesized through the oxidative self‐polymerization of dopamine under alkaline conditions. This emulates adhesive properties mussel foot proteins, allowing formation robust and stable organic coatings on various surfaces. Researchers have attempted to identify improve surface‐coating PDA by incorporating additional functional groups. review explores structural modifications molecules at chemistry level, with focus changes in catechol...

A cobalt-rhodium heterobimetallic nanoparticle (Co2Rh2/C)-catalyzed tandem reductive amination of aldehydes with nitroaromatics to sec-amines has been developed. The reaction proceeds without any additives under mild conditions (1 atm H2 and 25 °C). This procedure can be scaled up the gram scale, catalyst reused more than six times loss activity.

We disclose the unprecedented hybrid-ruthenium catalysis for distal meta-C-H activation. The catalyst was recyclable, as proven by various heterogeneity tests, and fully characterized with microscopic spectroscopic techniques, highlighting physical chemical stability. Thereby, proved broadly applicable alkylations of among others purine-based nucleosides natural product conjugates. Additionally, its versatility further reflected activations through visible-light irradiation, well...

Herein, we disclose a recyclable, hybrid manganese catalyst for site-selective azine C-H activation by weak amide assistance. The novel, reusable enabled C3-H arylation and alkylation with ample scope, was characterized detailed transmission electron microscopy analysis.

Abstract C7‐H‐funktionalisierte Indole sind allgegenwärtige Struktureinheiten in biologischen und pharmazeutischen Verbindungen, die für zahlreiche antivirale Wirkstoffe gegen SARS‐CoV oder HIV‐1 eingesetzt werden. Daher ist das Erreichen einer regioselektiven Funktionalisierung der C7‐H‐Position von Indolen bei gleichzeitiger Unterdrückung anderer C‐H‐Bindungen sehr gefragt. Hier beschreiben wir regioselektive C7‐H‐Aktivierung Indolen, durch Ruthenium(II)‐biscarboxylat‐Katalyse unter milden...

Abstract A degradable acetal‐backboned polymer was developed via palladium‐catalyzed hydroalkoxylation of dialkoxyallenes with diols. Dialkoxyallenes were easily prepared from the corresponding diols through propargylation, followed by isomerization. Polymers synthesized various combinations and dialkoxyallens in presence a palladium catalyst to produce acrolein acetal linkages. While backbones completely degraded into diols, recycling 1,4‐benzenedimethanol also demonstrated. The vinyl...

Abstract Herein, we disclose osmaelectrocatalyzed C−H activations that set the stage for electrooxidative alkyne annulations by benzoic acids. The osmium electrocatalysis enables site‐ and chemoselective with unique levels of selectivity. isolation unprecedented osmium(0) osmium(II) intermediates, along crystallographic characterization analyses spectrometric spectroscopic in operando techniques delineate a synergistic redox catalyst regime. Detailed mechanistic studies revealed facile...

Electrochemical C-H functionalizations are attractive transformations, as they capable of avoiding the use transition metals, pre-oxidized precursors, or suprastoichiometric amounts terminal oxidants. Herein an electrochemically tunable method was developed that enabled divergent formation cyclic amines imines by applying different reaction potentials. Detailed voltammetry analyses, coupled with chronopotentiometry experiments, were carried out to provide insight into mechanism, while atom...

During the last decades, merger of photocatalysis with transition metal chemistry has been surfaced as a sustainable tool in modern molecular syntheses. This Account highlights major advances synergistic photo-enabled C‒H activations. Inspired by our homogenous ruthenium- and copper-catalyzed activations absence an exogenous photosensitizer, this describes recent progress on heterogeneous photo-induced activation enabled immobilized hybrid catalysts until September 2021, topical focus...