A5103185680- Hemostasis and retained surgical items
- Surgical Sutures and Adhesives
- Effects of Radiation Exposure
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Food composition and properties
- Platelet Disorders and Treatments
- Blood Coagulation and Thrombosis Mechanisms
- Atrial Fibrillation Management and Outcomes
- Nanocomposite Films for Food Packaging
- Advanced Cellulose Research Studies
- Venous Thromboembolism Diagnosis and Management
- Hemophilia Treatment and Research
- Wound Healing and Treatments
- Heparin-Induced Thrombocytopenia and Thrombosis
- Intestinal and Peritoneal Adhesions
- Liver Disease Diagnosis and Treatment
- Polysaccharides Composition and Applications
- Glycosylation and Glycoproteins Research
- Drug Transport and Resistance Mechanisms
- Natural product bioactivities and synthesis
- Cell death mechanisms and regulation
- Electrospun Nanofibers in Biomedical Applications
- Radioactive element chemistry and processing
- RNA Interference and Gene Delivery
- Phagocytosis and Immune Regulation
Beijing Radiation Center
2018-2025
Henan University
2022-2024
Academy of Military Medical Sciences
2023
Beijing University of Technology
2005
Thiolutin, an inhibitor of the BRISC deubiquitinating enzyme complex, specifically and potently inhibits NLRP3 inflammasome activation.
Previous studies have suggested that Lycium barbarum (L. barbarum) has a radioprotective function, although more in-depth investigation is still required. We investigated the efficacy of extract fruits L. (LBE) and its mechanisms. Mice were exposed to 8.5 Gy, 5.5 or 6.0 Gy total body irradiation (TBI), survival rate, lymphocyte percentage, amount cytokines, viability irradiated cells, as well gut microbiome fecal metabolomics studied. LBE enhanced mice γ-ray TBI X-ray TBI. After TBI,...
Silver sulfadiazine (AgSD) is widely used in burn wound treatment due to its broad-spectrum antibacterial activity. However, application healing greatly hindered by the low solubility of AgSD particles and their cellular cytotoxicity. Herein, we studied safety vivo efficacy nano-sized silver loaded poloxamer thermosensitive hydrogel (NS/Gel). In NS/Gel, was prepared into nanosuspension (NS) improve enhance activity, whereas selected as a drug carrier NS achieve slow release reduced The acute...
Uncontrolled hemorrhage from trauma or surgery can lead to death. In this study, chitosan/kaolin (CSK) and chitosan/montmorillonite (CSMMT) composites were prepared chitosan (CS), kaolin (K), montmorillonite (MMT) as raw materials control bleeding. The physiochemical properties surface morphology of CSK CSMMT analyzed by Fourier transform infrared spectrometry (FT-IR), X-ray diffraction (XRD), scanning electron microscopy (SEM), zeta potentials, fluorescence (XRF). hemostatic mechanism was...
Radon (222Rn) is a naturally occurring radioactive gas. Forty percent of the natural radiation to which human body exposed comes from radon Long-term exposure high concentrations induces systemic damage. However, effect such on gut microbiota still remains unclear. We explored effects and its metabolites short-chain fatty acids (SCFAs) in BALB/c mice by cumulative inhalation at 30, 60, 120 working level months (WLM). The radon-exposed showed slow weight gain, decreased serum triglycerides...
Sepsis represents a syndromic response to infection and frequently acts as common pathway leading fatality in the context of various infectious diseases globally. The pathology severe sepsis is marked by an excess inflammation activated coagulation. A substantial contributor mortality patients widespread microvascular thrombosis-induced organ dysfunction. Multiple lines evidence support notion that induces endothelial damage, release glycosaminoglycans, potentially causing This review aims...
In order to investigate the effects of different drying methods on properties porous starch. The present study used four methods, namely hot air (HD), spray (SPD), vacuum freeze (FD) and supercritical carbon dioxide (SCD) prepare maize kudzu Findings indicated that physicochemical (e.g., morphology, crystallinity, enthalpy value, porosity, surface area water absorption capacity as well dye capacity, particle size) starch were significantly affected by method. Compared with other samples,...
Porous starch is a denatured product with high porosity, large specific surface area, and strong adsorption. It widely used in medicine, food, chemical industries. Native includes types A, B, C. In this study, the various materials, including potato kudzu starch, were to prepare different crystal of porous α-amylase glucoamylase. The structural characteristics measured using Fourier-transform infrared spectroscopy, scanning electron microscopy, X-ray diffraction, differential calorimetry....
A traumatic hemorrhage is fatal due to the great loss of blood in a short period time; however, there are few biomaterials that can stop bleeding quickly limited water absorption speed. Here, highly absorbent polymer (HPA), polyacrylate, was prepared as it has best structure-effectiveness relationship. Within very time (2 min), HPA continually absorbed until swelled up its 600 times weight; more importantly, porous structure comprised swollen dressing. This instantaneous swelling immediately...
Acute liver injury shares a common feature of hepatocytes death, immune system disorders, and cellular stress. Hepassocin (HPS) is hepatokine that has ability to promote proliferation protect rats from D-galactose (D-Gal)- or carbon tetrachloride (CCl4)-induced by stimulating preventing the high mortality rate, hepatocyte hepatic inflammation. In this paper, we generated pharmaceutical-grade recombinant human HPS using mammalian cells expression evaluated effects administration on...
The mole fraction of deacetylated monomeric units in chitosan (CS) molecules is referred to as CS's degree deacetylation (DD). In this study, 35 characteristic ions CS were detected using liquid chromatography-electrospray ionization-mass spectrometry (LC-ESI-MS/MS). relative response intensity ion pairs a single charge nine samples with varying DDs was analyzed 30 analytical methods. There good linear relationship between the determined ultrahigh performance (UP) LC-MS/MS and DD CS....