- Sarcoma Diagnosis and Treatment
- Cutaneous lymphoproliferative disorders research
- Fungal Infections and Studies
- Bone Tumor Diagnosis and Treatments
- Testicular diseases and treatments
- Salivary Gland Tumors Diagnosis and Treatment
- Sexual Differentiation and Disorders
- Musculoskeletal synovial abnormalities and treatments
- AI in cancer detection
- Global Cancer Incidence and Screening
- Head and Neck Surgical Oncology
- Ear and Head Tumors
- Hepatocellular Carcinoma Treatment and Prognosis
- Biomedical Text Mining and Ontologies
- Immune cells in cancer
- Cell Image Analysis Techniques
- Economic and Financial Impacts of Cancer
- Teratomas and Epidermoid Cysts
- Cardiovascular Issues in Pregnancy
- Breast Lesions and Carcinomas
- Head and Neck Anomalies
- Parasitic Infections and Diagnostics
- Tumors and Oncological Cases
- Amoebic Infections and Treatments
- Nail Diseases and Treatments
Aristotle University of Thessaloniki
2021-2024
AHEPA University Hospital
2024
Papageorgiou General Hospital
2024
Brookdale University Hospital and Medical Center
2023
Triple Negative Breast Cancer (TNBC) is characterized by distinct molecular subtypes with unique biological and clinical features. This systematic review aimed to identify articles examining the differences in tumor immune microenvironment (TIME) across different TNBC subtypes. Six studies meeting inclusion criteria were analyzed, utilizing gene expression profiling bioinformatic analyses classify samples into subtypes, as well immunohistochemistry cell deconvolution methods characterize...
Over the last 75 years, our understanding of Spitz lesions has undergone substantial evolution. Initially considered a specific type melanoma, perception shifted towards recognizing as spectrum comprising nevi, melanocytomas, and melanomas. are known for posing significant diagnostic challenge regarding distinction between benign neoplasms displaying atypical traits A comprehensive their molecular basis genomic aberrations significantly improved precision in classifying diagnosing these...
Carcinoma ex pleomorphic adenoma (Ca-ex-PA) is a rare tumor that arises from the malignant transformation of primary or recurrent adenoma. Despite being benign, adenomas can rarely undergo transformation. Risk factors include long-standing tumor, prior history radiation exposure, increased size, and disease. Ca-ex-PA usually affects patients between sixth eighth decades life, approximately 10 to 20 years after development Patients present with rapid expansion an already existing mass. We...
Diagnosis of Mycosis Fungoides (MF) may be challenging, due to its polymorphic nature. The use miRNAs as biomarkers assist in diagnosis has been investigated, mainly skin lesion biopsies. purpose this study is evaluate the plasma levels miR-146a and miR-155 MF patients investigate their association with SNPs genes. Plasma were quantified by RT-qPCR. Genomic DNA was used for SNPs’ genotyping Sanger sequencing. significantly higher vs. controls, early advanced patients. Both miRNAs’ stage IIB...
Abstract PURPOSE: Congenital cryptorchidism and retractile testes are two of the commonest abnormalities genitourinary system in boys. Orchidopexy is final surgical treatment for both clinical conditions. It can be applied either with traditional two-incision inguinal approach, or single-scrotal incision technique. This study aimed to investigate complications each orchidopexy procedure a pediatric surgery department, then compare single technique children diagnosed testes. METHODS: A...
Aim: To investigate the immunohistochemical (IHC) expression and diagnostic value of c-MYC, Cyclin D1, Ki-67/MIB-1 in follicular adenomas (FAs), carcinomas (FCs), anaplastic (ACs) thyroid gland, as well their corresponding adjacent, non-neoplastic tissue (NNTT). Materials Methods: We conducted a retrospective study patients who were pathologically diagnosed with FA, FC, or AC after total thyroidectomy. Tissue microarrays cores taken from neoplastic adjacent NNTT constructed....
Ossifying fibromyxoid tumor (OFMT) is a rare soft tissue neoplasm of uncertain origin, exhibiting wide clinical and morphological spectrum. It ranges from benign forms, which typically behave indolently, to malignant lesions with significant recurrence metastatic potential. The majority OFMTs harbor
Retrorectal hamartomas or tailgut cysts (TCs) are rare. In most cases, they asymptomatic and benign; however, rarely, undergo malignant transformation, mainly in the form of adenocarcinoma.A 55-year-old woman presented to our hospital with lower back pain. On magnetic resonance imaging, a large pelvic mass was found, which located on right ischiorectal fossa, extending minor pelvis. The patient underwent extensive surgical resection lesion through buttock. Histological examination confirmed...
Abstract is missing (Short communication)
Hepatic carcinoma expressing inhibin is a recently described neoplasm with varied architecture, including trabecular, pseudoglandular, follicular/microcystic, organoid, solid and tubular patterns of growth. We report case hepatic that occurred in 47-year-old woman presenting epigastric back pain. The tumor was located the left lobe measured 12 cm diameter. On immunohistochemical stains, neoplastic cells were positive for inhibin, as well cytokeratins 7, 8/18 19. There mild focal expression...
Background: Emerging data indicate that the cellular microenvironment and interleukins (IL) play a crucial role in mycosis fungoides (MF). We aimed to explore potential association between composition of expression IL-22 IL-17A MF skin lesions. Methods: The study encompassed 16 cases different stages, for which sufficient tissue immunohistochemistry frozen reverse transcription-polymerase chain reaction, both taken from same lesion, were available. Histological evaluation eosinophils,...
Congenital adrenal hyperplasia (CAH) refers to a group of autonomic disorders due enzyme deficiency for the biosynthesis steroid hormones. These entail an increase in ACTH levels and as followed by hyperplasia. CAH is categorized into two types, classic non-classic. In common type we have 21-hydroxylase observed prevalence 1 per 5000 145,000 births. We insufficient aldosterone cortisol production result, elevated plasma levels, with subsequent that this entails, depending on level...