A5038192690- HIV Research and Treatment
- Herpesvirus Infections and Treatments
- RNA and protein synthesis mechanisms
- Cytomegalovirus and herpesvirus research
Institute of Microbial Technology
2020-2021
Academy of Scientific and Innovative Research
2020-2021
Evaluating the structure-function relationship of viral envelope (Env) evolution and development broadly cross-neutralizing antibodies (bnAbs) in natural infection can inform rational immunogen design. In present study, we examined magnitude specificity autologous neutralizing induced rabbits by a novel HIV-1 clade C Env protein (1PGE-THIVC) vis-à-vis those developed an elite neutralizer from whom env sequence was obtained that used to prepare soluble protein. The 1PGE-THIVC trimer displayed...
Abstract Evaluating the structure-function relationship of viral envelope (Env) evolution and development broadly cross-neutralizing antibodies (bnAbs) in natural infection can inform rational immunogen design. In present study, we examined magnitude specificity autologous neutralizing induced rabbits by a novel HIV-1 clade C Env protein (1PGE-THIVC) vis-à-vis those developed an elite neutralizer from whom env sequence was obtained that used to prepare soluble protein. The thermostable...