Gengyu Chen

ORCID: 0000-0002-9254-1773
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About
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Research Areas
  • Cancer-related molecular mechanisms research
  • Thyroid Cancer Diagnosis and Treatment
  • Circular RNAs in diseases
  • MicroRNA in disease regulation
  • Head and Neck Anomalies
  • Teratomas and Epidermoid Cysts
  • Flood Risk Assessment and Management
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Salivary Gland Tumors Diagnosis and Treatment
  • Inflammasome and immune disorders
  • Tumors and Oncological Cases
  • Urban Green Space and Health
  • Biomarkers in Disease Mechanisms
  • Land Use and Ecosystem Services
  • S100 Proteins and Annexins
  • Cancer and Skin Lesions
  • Breast Lesions and Carcinomas
  • Breast Cancer Treatment Studies
  • Protease and Inhibitor Mechanisms

Fourth People’s Hospital of Jinan
2019-2025

Zhengzhou Central Hospital
2023

The Fourth People's Hospital
2023

South China Agricultural University
2021

Shandong University
2018

Shandong Provincial Hospital
2018

10.22541/au.173657721.16912852/v1 preprint EN Authorea (Authorea) 2025-01-11

Abstract Papillary thyroid carcinoma (PTC) is the most prevalent cancer in endocrine system, and number of patients diagnosed with PTC has been increasing rapidly recent years. Previous studies have reported that miR‐145 plays an important role many kinds cancers, but its function remains unclear. In this study, we found compared to paracancerous tissues, level expression was significantly downregulated tissues. When overexpressed, migration invasion cells were suppressed vitro. addition,...

10.1002/jcb.29604 article EN Journal of Cellular Biochemistry 2020-01-07

In order to examine the inhibitory effects of microRNA (miR)‑26b‑5p on thyroid cancer (TC), clinicopathological features and pathological tissues 67 patients were collected. The expression levels miR‑26b‑5p detected in TC paracarcinoma by quantitative polymerase chain reaction, association between was analyzed using t‑test or one‑way analysis variance. addition, B‑CPAP cells infected with a lentivirus induce overexpression proliferation Cell Counting kit‑8. Subsequently, migration invasion...

10.3892/mmr.2019.10315 article EN cc-by-nc-nd Molecular Medicine Reports 2019-05-31

Papillary thyroid carcinoma (PTC) is the most common form of cancer, and its incidence on rise. It has been reported that some matrix metalloproteinases (MMPs) are abnormally expressed in PTC can be used as diagnostic markers. However, few studies have explored underlying mechanisms by which MMPs promote tumor progression. In this study, we microarray analysis to compare variations gene expression within cell populations their adjacent normal tissues found MMP-11 was differentially MMP. To...

10.1002/jcb.27500 article EN Journal of Cellular Biochemistry 2018-09-01

Ignoring the function of natural landscapes in rapid development urbanization, and especially conservation historic urban landscapes, is still obvious today, this has caused a large decrease space, loss habitats, an increase disasters. The resilience whole city parts it, such as areas where historical process man nature have been recorded, well interaction between nature, economy, culture, not strong enough to maintain stability ecosystems. It misleading think that can be built area without...

10.3390/su131810356 article EN Sustainability 2021-09-16

Occult thyroid papillary carcinoma (OTPC) is typically characterized by initial presentation with cervical lymph node metastasis and can be detected through ultrasound. However, the sole manifestation was a submandibular solid-cystic mass. High-frequency ultrasound, enhanced multislice computed tomography (CT) scan, function tests revealed no abnormalities, which relatively uncommon.A 24-year-old Chinese female, who studied at university in Shandong Province, presented to clinic June 2019...

10.12998/wjcc.v11.i29.7253 article EN World Journal of Clinical Cases 2023-10-13
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